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Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein.
Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein.
period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.
period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.
miRNAs are required for generating a time delay critical for the circadian oscillator.
miRNAs are required for generating a time delay critical for the circadian oscillator.
Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.
Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.
 3'-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation.
3'-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation.
Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.
Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.
Stoichiometric relationship among clock proteins determines robustness of circadian rhythms.
Stoichiometric relationship among clock proteins determines robustness of circadian rhythms.