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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Heparin does not appear to improve overall outcomes when used for ischemic stroke or within the first 2 weeks of a cardioembolic stroke. (SOR B, extrapolated from meta-analyses of multiple heparinoids.)
A decrease in dietary fat does not alter the risk of coronary heart disease (CHD), stroke, or cardiovascular disease (CVD) in postmenopausal women (SOR: B, based on a single RCT), nor does it significantly alter CHD in women aged 30 to...
Coenzyme Q10 (CoQ10) may lower systolic and diastolic blood pressures in patients with primary hypertension, but is not recommended as an antihypertensive treatment (SOR: C, systematic review of low-quality RCTs using disease-oriented...
Racial Disparity in the Associations of Microalbuminuria and Macroalbuminuria with Odds of Hypertension: Results from the NHANES Study in the United States
Background. Limited information is available on whether the associations of microalbuminuria and macroalbuminuria with the odds of hypertension differ among non-Hispanic Whites, non-Hispanic Blacks, and Hispanics. Methods. Cross...
In family studies, phenotypic similarities between relatives yield information on the overall contribution of genes to trait variation. Large samples are important for these family studies, especially when comparing heritability between...
Women who smoke, have hypertension, hyperlipidemia, or factor V Leiden deficiency and take oral contraception (OC) are at increased risk of myocardial infarction (MI). Third-generation OCs and low-dose OCs are not associated with...
Several ablative therapies are effective. However, endovenous laser ablation (EVLA) has a higher 5-year success rate than surgical stripping, ultrasound-guided foam sclerotherapy (UGFS), and radiofre-quency ablation (RFA). EVLA is also...
Myocardial infarction (MI) is a major risk for ventricular arrhythmia. Pause-triggered ventricular arrhythmia can be caused by increased myofilament Ca binding due to sarcomeric mutations or Ca-sensitizing compounds. Myofilament Ca...
In patients with peripheral vascular disease (PVD), a structured exercise program improves walking distances and is relatively low risk and low cost. Lipid-lowering therapy reduces the risk of cardiovascular events and also increases...
A large body of evidence links antagonism-related traits with cardiovascular outcomes, but less is known about how psychological traits are associated with intermediate markers of cardiovascular disease. Using a large, community-based...
Objectives: Pharmacist-managed collaborative services in a family practice setting are described, and diabetes and hypertension outcomes are assessed. Methods: Pharmacist-managed clinics, pharmacotherapy consultations, and drug...
The following interventions improve important outcomes in patients with systolic heart failure (all SORs: A, based on meta-analyses): • Angiotensin converting enzyme (ACE) inhibitors reduce mortality, repeat myocardial infarction (MI), ...
Increased salt intake, compression stockings, and midodrine can reduce symptoms related to benign orthostatic hypotension. (SOR B, based on a single study of each intervention.) Counterpressure measures are safe, easy, reliable...
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