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Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.
Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.
Full Title:
Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.
Creator:
O'Neal-Moffitt, G, Delic, V, Bradshaw, P C, Olcese, J
Description:
Alzheimer's disease (AD) underlies dementia for millions of people worldwide, and its occurrence is set to double in the next 20 years. Currently, approved drugs for treating AD only marginally ameliorate cognitive deficits, and provide...
Date:
2015-07-11
Format:
journal article, text
Collection:
Department of Biomedical Sciences
Identifiers:
FSU_pmch_26159703, 10.1186/s13024-015-0027-6, PMC4702331, 26159703
URLs:
http://purl.flvc.org/fsu/fd/FSU_pmch_26159703
Repository ID:
fsu:523940
Genome-wide association study identifies 74 loci associated with educational attainment.
Genome-wide association study identifies 74 loci associated with educational attainment.
Full Title:
Genome-wide association study identifies 74 loci associated with educational attainment.
Creator:
Okbay, Aysu, Beauchamp, Jonathan P, Fontana, Mark Alan, Lee, James J, Pers, Tune H, Rietveld, Cornelius A, Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S Fleur W, Oskarsson, Sven, Pickrell, Joseph K, Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S, Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H, Pina Concas, Maria, Derringer, Jaime, Furlotte, Nicholas A, Galesloot, Tessel E, Girotto, Giorgia, Gupta, Richa, Hall, Leanne M, Harris, Sarah E, Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E, Kaasik, Kadri, Kalafati, Ioanna P, Karlsson, Robert, Kong, Augustine, Lahti, Jari, van der Lee, Sven J, deLeeuw, Christiaan, Lind, Penelope A, Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B, van der Most, Peter J, Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J, Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E, Shi, Jianxin, Smith, Albert V, Poot, Raymond A, St Pourcain, Beate, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z, Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E, Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A, Campbell, Harry, Cappuccio, Francesco P, Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M, Faul, Jessica D, Feitosa, Mary F, Forstner, Andreas J, Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V, Harris, Tamara B, Heath, Andrew C, Hocking, Lynne J, Holliday, Elizabeth G, Homuth, Georg, Horan, Michael A, Hottenga, Jouke-Jan, de Jager, Philip L, Joshi, Peter K, Jugessur, Astanand, Kaakinen, Marika A, Kähönen, Mika, Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A L M, Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T, Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J, Lebreton, Maël P, Levinson, Douglas F, Lichtenstein, Paul, Lichtner, Liewald, David C M, Loukola, Anu, Madden, Pamela A, Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E, Marques-Vidal, Pedro, Meddens, Gerardus A, McMahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W, Myhre, Ronny, Nelson, Christopher P, Nyholt, Dale R, Ollier, William E R, Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L, Petrovic, Katja E, Porteous, David J, Räikkönen, Katri, Ring, Susan M, Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R, Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J, Smith, Blair H, Smith, Jennifer A, Staessen, Jan A, Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D, Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J A, Venturini, Cristina, Vinkhuyzen, Anna A E, Völker, Uwe, Völzke, Henry, Vonk, Judith M, Vozzi, Diego, Waage, Johannes, Ware, Erin B, Willemsen, Gonneke, Attia, John R, Bennett, David A, Berger, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I, Borecki, Ingrid B, Bültmann, Ute, Chabris, Christopher F, Cucca, Francesco, Cusi, Daniele, Deary, Ian J, Dedoussis, George V, van Duijn, Cornelia M, Eriksson, Johan G, Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V, Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J F, Gudnason, Vilmundur, van der Harst, Pim, Hayward, Caroline, Hinds, Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G, Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L R, Lehtimäki, Terho, Lehrer, Steven F, Magnusson, Patrik K E, Martin, Nicholas G, McGue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W J H, Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Samani, Nilesh J, Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I A, Spector, Tim D, Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A Roy, Timpson, Nicholas J, Tiemeier, Henning, Tung, Joyce Y, Uitterlinden, André G, Vitart, Veronique, Vollenweider, Weir, David R, Wilson, James F, Wright, Alan F, Conley, Dalton C, Krueger, Robert F, Davey Smith, Hofman, Albert, Laibson, David I, Medland, Meyer, Michelle N, Yang, Jian, Johannesson, Magnus, Visscher, Peter M, Esko, Tõnu, Koellinger, Philipp D, Cesarini, Benjamin, Daniel J
Description:
Educational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least 20% of the variation across individuals. Here we report the results of a genome-wide...
Date:
2016-05-26
Format:
journal article, text
Collection:
Department of Geriatrics
Identifiers:
FSU_pmch_27225129, 10.1038/nature17671, PMC4883595, 27225129, nature17671
URLs:
http://purl.flvc.org/fsu/fd/FSU_pmch_27225129
Repository ID:
fsu:623043