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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
A key challenge for modern chemistry is the production of mesoscopic complexity and hierarchical order to ultimately bridge the gap between the molecular world and functional microdevices. As proof of concept, nature shows unambiguously...
Solid-state NMR takes advantage of studying membrane proteins in a native membrane-like lipid bilayer and has been used for generating exciting results. The magic angle spinning ssNMR of randomly oriented liposomes provides complementary...
The work in this dissertation presents methods for study of glucose stimulated insulin secretion as well as other hormones involved in glucose homeostasis. A microfluidic system was developed to investigate the entrainment of insulin...
Molecular dynamics (MD) simulations have advanced greatly in the recent decades, but are not without their limitations. This work first details the pitfalls of MD simulations, then presents the details of a new, robust method, orthogonal...
Optical technology in biophysics has seen significant growth with development of high resolution techniques, like single-molecule FRET, to investigate biological structures under native conditions. Additionally, with the rise in gold...
Vortex waves are striking spatial-temporal patterns and observed in diverse systems, such as active galaxies, catalytic reactions, and even biological systems. In the heart, vortex patterns of electrical waves are linked to ventricular...
Zinc(II) ions and reactive oxygen species (ROS) have had broad implications on the health and wellness of living beings. This dissertation focuses on imaging techniques aimed at unraveling the function of these species in various...
This dissertation is organized in two parts. The first part summarizes work in a newly developed synthetic route to perovskite-like MOFs, offering control over particle size and morphology. The second part of the dissertation cover...
Murine adenosine deaminase (ADA), a 40 kDa enzyme, catalyzes the hydrolytic deamination of adenosine to form inosine, enhancing the rate of the spontaneous reaction by more than than 1011 times the rate of the non-catalyzed reaction....
Interfacing inorganic nanoparticles with biological systems to develop a variety of novel imaging, sensing and diagnostic tools has generated great interest and much activity over the past two decades. However, the effectiveness of this...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
