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The striated muscle Z-line is a complex network of proteins in which N-terminal domains of titin interact with the actin filament cross-linker alpha-actinin, and other proteins to establish and maintain the structural integrity of the...
We previously discovered a large titin-like protein - c-titin - in chicken epithelial brush border and human blood platelet extracts that binds alpha-actinin and organizes arrays of myosin II bipolar filaments in vitro. RT-PCR analysis...
Biocompatible coatings are often used to improve fixation between implants and tissues. Polyelectrolyte multilayer (PEMU) coatings built layer by layer with alternating pairs of polyelectrolytes can be tuned to improve cell interactions...
To improve the design of prostheses surfaces, our research group investigates how biocompatible polyelectrolyte multilayers (PEMUs) can be constructed to serve as coatings for biomedical implants, providing a versatile, inexpensive, and...
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