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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Statisticians often encounter data in the form of a combination of discrete and continuous outcomes. A special case is zero-inflated longitudinal data where the response variable has a large portion of zeros. These data exhibit...
Polychotomous quantal response models are widely used in medical and econometric studies to analyze categorical or ordinal data. In this study, we apply the Bayesian methodology through a mixed-effects polychotomous quantal response...
Image analysis often requires dimension reduction before statistical analysis, in order to apply sophisticated procedures. Motivated by eventual applications, a variety of criteria have been proposed: reconstruction error, class...
Shape analysis of curves and surfaces is a very important tool in many applications ranging from computer vision to bioinformatics and medical imaging. There are many difficulties when analyzing shapes of parameterized curves and...
Forecasting a univariate target time series in high dimensions with very many predictors poses challenges in statistical learning and modeling. First, many nuisance time series exist and need to be removed. Second, from economic theories...
In this thesis, based on an orthonormal series expansion, we propose a new nonparametric method to estimate copula density functions. Since the basis coefficients turn out to be expectations, empirical averages are used to estimate these...
We perform a quasi-3D Bayesian inversion of oceanographic tracer data from the South Atlantic Ocean. Initially we are considering one active neutral density layer with an upper and lower boundary. The available hydrographic data is...
This dissertation introduces and assesses an algorithm to generate confidence bands for a regression function or a main effect when multiple data sets are available. In particular it proposes to construct confidence bands for different...
In this thesis we investigate statistical modelling of neural activity in the brain. We first develop a framework which is an extension of the state-space Generalized Linear Model (GLM) by Eden and colleagues [20] to include the effects...
This thesis presents a Bayesian approach to Meta-Regression and Individual Patient Data (IPD) Meta-analysis. The focus of the research is on establishing the relationship between Body Mass Index (BMI) and all-cause mortality. This has...
Risk prediction plays an important role in clinical medicine. It not only helps in educating patients to improve life style and in targeting individuals at high risk, but also guides treatment decisions. So far, various instruments have...
Constructing generative models for functional observations is an important task in statistical function analysis. In general, functional data contains both phase (or x or horizontal) and amplitude (or y or vertical) variability....
The stochastic modeling of financial assets is essential to the valuation of financial products and investment decisions. These models are governed by certain parameters that are estimated through a process known as calibration. Current...
Vast amounts of biomedical information are stored in scientific literature, easily accessed through publicly available databases. Relationships among biomedical terms constitute a major part of our biological knowledge. Acquiring such...
We propose a Riemannian framework for shape analysis of annotated curves, curves that have certain attributes defined along them, in addition to their geometries.These attributes may be in form of vector-valued functions, discrete...
A class of hierarchical Bayesian models is introduced for adverse birth outcomes such as preterm birth, which are assumed to follow a conditional binomial distribution. The log-odds of an adverse outcome in a particular county, logit(p(i...
Many characteristics for predicting death due to coronary heart disease are measured on a continuous scale. These characteristics, however, are often categorized for clinical use and to aid in treatment decisions. We would like to derive...
Variable selection is an important aspect of modeling. Its aim is to distinguish between the authentic variables which are important in predicting outcome, and the noise variables which possess little to no predictive value. In other...
Different methods have been proposed to model the J-shaped or U-shaped relationship between a risk factor and mortality so that the optimal risk-factor value (nadir) associated with the lowest mortality can be estimated. The basic model...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.