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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Numerous studies of local adaptation have shown that populations can adapt quickly to local environmental conditions. Other studies have shown that sister species tend to occur in different environments. Recent work has gone a long way...
Computational analysis of cDNA sequences from multiple organisms suggests that a large portion of transcribed DNA does not code for a functional protein. As studies begin to delve into the possible functions of these noncoding...
Investigation of the Effects of G9a Knockout on Subnuclear Localization and Replication Timing of G9a Repressed Genes When Integrated into an Early Replicating Region
G9a is a histone methyltransferase that is responsible for dimethylation of histone 3 lysine 9 (H3K9me2) this chromatin marker is typically associated with transcriptional silencing. Following conditional knockout of G9a in mouse...
One of the events leading to a cell's commitment to a new cell cycle resulting in cell division is upregulation of the replication-dependent histone gene family. Our laboratory has previously identified a coding region activating...
Reversible phosphorylation plays an integral role in the regulation of eukaryotic cellular proteins, especially transcription factors. YY1 is a multifunctional transcription factor involved in the regulation of a wide spectrum of...
The time at which DNA replicates during S-phase (replication timing; RT) is a precisely orchestrated, yet large-scale epigenetic property that offers an unparalleled window into the structure and regulation of the genome. While the...
Reversible protein phosphorylation plays an integral role in the regulation of eukaryotic cellular signaling, especially for transcription factors. Yin Yang 1 (YY1) is a ubiquitously expressed and highly conserved multifunctional...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
