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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Objective: Poverty is a risk factor for obesity. Using homelessness as a marker for poverty, we examined the prevalence of obesity in Leon County, Florida's homeless population to determine their attitudes and perceptions towards the...
Compared with hysterectomy or myomectomy, UAE for treating fibroids results in similar patient satisfaction. UAE is associated with fewer blood transfusions, shorter hospital stays, and quicker resumption of normal activities than...
Profound disparities exist among families who experience adverse infant health outcomes (i.e. preterm birth and low birth weight), yet much is still unclear regarding the factors that predict disparate outcomes. In order to address this...
Previous research suggests that strict rest following a concussion may prolong symptom presentation, but rest is still one of the most common treatments. Aerobic exercise has effectively reduced symptom burden and exercise intolerance in...
We examined developmental trends in personality traits over a 42-year time period by using data from the Baltimore Longitudinal Study on Aging (N = 2, 359; individuals aged 17-98), collected from 1958 to 2002. Hierarchical linear modeling...
Background: Lower-back stress fractures are a common injury in thirteen to eighteen year old competitive female gymnasts, but the causes of this injury, outside of the mechanical stress of the sport, have not been thoroughly explored....
Short Hairpin RNAs Delivered by Lentiviral Vector Transduction Trigger RIG-I-Mediated IFN Activation and Isolation of HCV with Enhanced Kinetics and Viral Assembly
Activation of the type I interferon (IFN) pathway by small interfering RNA (siRNA) is a major contributor to the off-target effects of RNA interference in mammalian cells. While IFN induction complicates gene function studies, ...
In the present research, we examined the effects of age, cohort, and time of measurement on well-being across adulthood. Cross-sectional and longitudinal analyses of two independent samples-one with more than 10, 000 repeated assessments...
Objectives Our library has provided 24/7 access for student study space since 2010. This service has functioned as anticipated with minor policy breaches in 2010 and 2013. The purpose of this study was to determine how well 24/7 access...
Purpose: To examine pulse oximetry (PO) levels in healthy adult subjects across the adult age span, and to examine the same in a sample of individuals with severe and very severe chronic obstructive pulmonary disease (COPD), and to...
The hepatitis C virus (HCV) is a serious health threat globally. Current therapies are not tolerated well, have a low response rate, and there is no available vaccine. New viral targets for drugs are urgently needed. The aim of this...
The purpose of this study was to examine the effect of live versus recorded music on the nutritional intake of older adults during mealtimes in an assisted living facility. Nutritional health is an important component of maintaining...
The ultimate goal of health literacy is to improve care by enhancing the patient's quality of life, maximizing clinical outcomes, and reducing inequities in health. Successful restructuring of the healthcare system to make it more...
The rabbit is an important and de facto animal model in the study of ischemic disease and angiogenic therapy. Additionally, fibroblast growth factor 1 (FGF-1) is emerging as one of the most important growth factors for novel...
Librarians have provided reference and research support for faculty to varying degrees for many years, and librarian support is needed more than ever today with the rapidly evolving nature of library resources and online information....
We examined the influence of personality traits on mean levels and age trends in 4 single-item measures of self-rated health: general rating, comparison to age peers, comparison to past health, and expectations for future health....
Background: Athletes continue to strive for an edge over the competition. In recent years, dietary nitrate supplementation, particularly in the form of beetroot juice, has been shown to improve oxygen cost economy in endurance-focused...
Hypertrophic Cardiomyopathy (HCM) is a common primary cardiac disorder defined by a hypertrophied left ventricle, is one of the main causes of sudden death in young athletes, and has been associated with mutations in most sarcomeric...
Small changes in the dosing of levothyroxine (±25 mcg) are associated with large changes in serum thyroid-stimulating hormone (TSH) and free thyroxine (FT4) concentrations, but not with measurable changes in hypothyroid symptoms, well...
The purpose of this study is to determine the effects of cognitive load on parameters of gait in a person with traumatic brain injury and a person with no neurological deficits. Injurious falls are the leading cause of traumatic brain...
Distribution of orientations of myosin was examined in ex-vivo myofibrils from hearts of transgenic (Tg) mice expressing Familial Hypertrophic Cardiomyopathy (FHC) troponin T (TnT) mutations I79N, F110I and R278C. Humans are heterozygous...
Cutaneous malignant melanoma is an aggressive disease of poor prognosis. Clinical and experimental studies have provided major insight into the pathogenesis of the disease, including the functional interaction between melanoma cells and...
Smoking is a leading global cause of disease and mortality. We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association with smoking-related behavioral traits. Our final data set...
Tissue kallikrein KLK1 and the kallikrein-related peptidases KLK2-15 are a subfamily of serine proteases that have defined or proposed roles in a range of central nervous system (CNS) and non-CNS pathologies. To further understand their...
The goals of this cross-sectional study were to explore correlates of walking speed in a large wide age-ranged population and to identify factors affecting lower walking speed at older ages. Participants were 3, 872 community-dwelling...
Several ablative therapies are effective. However, endovenous laser ablation (EVLA) has a higher 5-year success rate than surgical stripping, ultrasound-guided foam sclerotherapy (UGFS), and radiofre-quency ablation (RFA). EVLA is also...
A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101, 069 individuals and a replication sample of 25, 490. Three independent single-nucleotide polymorphisms (SNPs) are genome-wide...
We previously reported the activation profiles of the human kallikrein-related peptidases (KLKs) as determined from a KLK pro-peptide fusion-protein system. That report described the activity profiles of 12 of the 15 mature KLKs versus...
This study examines the association between personality traits and bruxism, the repetitive grinding or clenching of teeth. Community-dwelling participants (N = 470) had a comprehensive oral examination by a dentist and completed a dental...
Obesity is a known pathological condition associated with impaired glucose homeostasis leading to type 2 diabetes and increased susceptibility to loss of skeletal muscle mass and function. Recent investigations have demonstrated...
Caring for underserved patients presents great challenges for community practices. This report discusses an interdisciplinary underserved practice that was reorganized in 2008 allowing for practice improvement and greater community...
Personality can be thought of as a set of characteristics that influence people's thoughts, feelings and behavior across a variety of settings. Variation in personality is predictive of many outcomes in life, including mental health....
Cardiac injury induces myocardial expression of the thyroid hormone inactivating type 3 deiodinase (D3), which in turn dampens local thyroid hormone signaling. Here, we show that the D3 gene (Dio3) is a tissue-specific imprinted gene in...
Methodological arguments are usually invoked to explain variations in the structure of affect. Using self-rated affect from Italian samples (N=600), we show that individual difference variables related to affective differentiation can...
In the female rat, secretion of prolactin is tightly controlled by a complex interplay of both stimulatory and inhibitory hypothalamic factors. In addition, the profile of prolactin release in the ovariectomized rat treated with...
Background: Obesity is an ongoing socio-economic worldwide epidemic and major modifiable risk for cardiovascular disease (CVD), which continues to be the main determinant of all-cause mortality. A potential mechanism by which obesity...
Rank-order consistency of personality traits increases from childhood to age 30. After that, different summaries of the literature predict a plateau at age 30, or at age 50, or a curvilinear peak in consistency at age 50. These...
The Effects of Twelve Weeks of Whole-Body Vibration Training and Low-Intensity Resistance Exercise Training on Arterial Function, Muscle Strength, and Physical Performance in Dynapenic Postmenopausal Women
Cardiovascular disease (CVD) remains the leading cause of death in the modern world, markedly in postmenopausal women. Increased arterial stiffness, measured as increased pulse wave velocity (PWV), and endothelial dysfunction are large...
In two studies, the present research tested the phenomenology and content of autobiographical memory as distinct mediators between attachment avoidance and anxiety and depressive symptoms. In Study 1, participants (N = 454) completed...
Weight loss therapy consisting of 20 to 30 lifestyle-modification group visits is associated with modest (4–8 kg) weight loss. (SOR A, based on homogeneous randomized controlled trials [RCTs].) For patients who participate in group...
In this paper I analyze and critique Gert's views on death, tracing the evolution of his ideas throughout his career. I argue that the definitions-criteria-tests framework that he and his colleagues introduced, along with their approach...
The human kallikrein-related peptidases (KLKs) comprise 15 members (KLK1-15) and are the single largest family of serine proteases. The KLKs are utilized, or proposed, as clinically important biomarkers and therapeutic targets of...
The present research addressed fundamental questions about the visual perspective of autobiographical memories: Are stable personality characteristics associated with visual perspective? Does visual perspective influence the memory's...
Pelvic floor muscle training (PFMT) is superior to no treatment or inactive controls, and is effective in nonpregnant, pregnant, and postpartum women. (SOR A, based on meta-analyses.) The clinical value of habit retraining, timed voiding...
Weight discrimination is prevalent in American society. Although associated consistently with psychological and economic outcomes, less is known about whether weight discrimination is associated with longitudinal changes in obesity. The...
BACKGROUND: Physical inactivity plays a central role in the age-related decline in muscle strength, an important component in the process leading to disability. Personality, a significant determinant of health behaviors including...
Cefotaxime, ceftriaxone, and respiratory fluoroquinolones are recommended for influenza-associated pneumonia. Oseltamivir and zanamivir can be used to reduce viral shedding in hospitalized patients with influenza, with or without...
The authors investigated built environment (BE) factors in urban neighborhoods in DeKalb County, Georgia. Each volunteering, consenting senior was placed into one of two groups: walking tours outside, then discussions (n=37); and focus...
Myocardial infarction (MI) is a major risk for ventricular arrhythmia. Pause-triggered ventricular arrhythmia can be caused by increased myofilament Ca binding due to sarcomeric mutations or Ca-sensitizing compounds. Myofilament Ca...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
