Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
An attempt has been made to improve a crystal contact of human acidic fibroblast growth factor (haFGF; 140 amino acids) to control the crystal growth, because haFGF crystallizes only as a thin-plate form, yielding crystals suitable for X...
Mutations in TNNT2, encoding cardiac troponin T, commonly shows early onset, aggressive dilated cardiomyopathy (DCM). This observation may influence the decision of whether to undertake clinical genetic testing for TNNT2 in later onset...
Aside from existing drug therapies, certain lifestyle and nutritional factors are known to reduce the risk of osteoporosis. Among the nutritional factors, dried plum or prunes (Prunus domestica L.) is the most effective fruit in both...
The management and prognosis of HIV disease has changed dramatically since the introduction of combination HIV antiretroviral therapy in 1996. Thus, the number of older adults with HIV is increasing partly because people with HIV are...
Menopause leads to an increased risk for osteoporosis in women. Although drug therapies exist, increasing numbers of people prefer alternative therapies such as dietary supplements, e.g. calcium, vitamin D, and collagen hydrolysates for...
American culture and public policy have long held a split vision about the aged: vulnerability, dependency, and special need for law and policy to act as a protective shield versus the aged as independent, self-reliant, and capable of...
There is growing evidence that personality traits are affected by many genes, all of which have very small effects. As an alternative to the largely unsuccessful search for individual polymorphisms associated with personality traits, the...
The process of normal wound repair after tissue injury follows a closely regulated sequence involving inflammation, the recruitment, activation and proliferation of fibroblasts and the secretion of extracellular matrix, which culminates...
Unhealthy lipid levels are among the leading controllable risk factors for coronary heart disease. To identify the psychological factors associated with dyslipidemia, this study investigates the personality correlates of cholesterol ...
National income has a pervasive influence on the perception of ingroup stereotypes, with high status and wealthy targets perceived as more competent. In two studies we investigated the degree to which economic wealth of raters related to...
Progesterone, a neurosteroid, reduces inflammation, cell death and oxidative stress while improving cognitive recovery following severe traumatic brain injury (TBI). However, studies regarding the effects of Prog after mild traumatic...
Aspartame may be associated with headaches in susceptible individuals (SOR B, based on a small crossover study.) Monosodium glutamate (MSG) is associated with a range of constitutional symptoms; however, with blinding, responses to MSG...
Brain-derived neurotrophic factor (BDNF) regulates synaptic plasticity and neurotransmission, and has been linked to neuroticism, a major risk factor for psychiatric disorders. A recent genome-wide association (GWA) scan, however, found...
Patients with Bell's palsy have higher cure rates when treated with oral prednisolone within 72 hours of onset (SOR B, based on a single randomized controlled trial), but it is unclear what effect this therapy would have on patients with...
Racial Disparity in the Associations of Microalbuminuria and Macroalbuminuria with Odds of Hypertension: Results from the NHANES Study in the United States
Background. Limited information is available on whether the associations of microalbuminuria and macroalbuminuria with the odds of hypertension differ among non-Hispanic Whites, non-Hispanic Blacks, and Hispanics. Methods. Cross...
The present research addresses the dynamic transaction between extrinsic (occupational prestige, income) and intrinsic (job satisfaction) career success and the Five-Factor Model of personality. Participants (N = 731) completed a...
I defend a theory of mental representation that satisfies naturalistic constraints. Briefly, we begin by distinguishing (i) what makes something a representation from (ii) given that a thing is a representation, what determines what it...
The polymorphism in the serotonin transporter gene promoter region (5-HTTLPR) is by far the most studied variant hypothesized to influence Neuroticism-related personality traits. The results of previous studies have been mixed and appear...
Objective: Message framing is a theoretically grounded health communication strategy designed to motivate action by emphasizing the benefits of engaging in a particular behavior (gains) or the costs of failing to engage in the behavior ...
In human cardiomyopathy, anatomical abnormalities such as hypertrophy and fibrosis contribute to the risk of ventricular arrhythmias and sudden death. Here we have shown that increased myofilament Ca2+ sensitivity, also a common feature...
The structure and psychometric characteristics of the NEO Personality Inventory-3 (NEO-PI-3), a more readable version of the Revised NEO Personality Inventory (NEO-PI-R), are examined and compared with NEO-PI-R characteristics using data...
In family studies, phenotypic similarities between relatives yield information on the overall contribution of genes to trait variation. Large samples are important for these family studies, especially when comparing heritability between...
Past research suggests that focusing on what has not yet been accomplished (goal focus) signals a lack of progress towards one's high commitment goals and inspires greater motivation than does focusing on what has already been...
Recommended first-line antibiotic therapy for community-acquired (CA) pneumonia is 5 days of a macrolide in adults and 3 to 5 days of amoxicillin in children. (SOR: C, based on consensus guidelines.) In otherwise healthy adults, there is...
S(1)' and S(2)' Subsite Specificities of Human Plasma Kallikrein and Tissue Kallikrein 1 for the Hydrolysis of Peptides Derived from the Bradykinin Domain of Human Kininogen
The S(1)' and S(2)' subsite specificities of human tissue kallikrein 1 (KLK1) and human plasma kallikrein (HPK) were examined with the peptide series Abz-GFSPFRXSRIQ-EDDnp and Abz-GFSPFRSXRIQ-EDDnp [X=natural amino acids or S(PO(3)H(2))]...
The Screener and Opioid Assessment Measure for Patients with Chronic Pain (SOAAP) and the Opioid Risk Tool (ORT) are both validated tools that screen for future problems with prescription opioids. The ORT has been more rigorously studied...
While protease-activated receptors (PARs) are known to mediate signaling events in CNS, contributing both to normal function and pathogenesis, the endogenous activators of CNS PARs are poorly characterized. In this study, we test the...
Women who smoke, have hypertension, hyperlipidemia, or factor V Leiden deficiency and take oral contraception (OC) are at increased risk of myocardial infarction (MI). Third-generation OCs and low-dose OCs are not associated with...
If you make health care decisions for another adult person—or might at some future point—this handbook is for you. Learn what it means to become a "health care substitute."
Kallikrein-related peptidase 6 (KLK6) is a trypsin-like serine protease upregulated at sites of central nervous system (CNS) injury, including de novo expression by reactive astrocytes, yet its physiological actions are largely undefined...
BACKGROUND: High Neuroticism and low Conscientiousness are frequently implicated in health-risk behaviors, such as smoking and overeating, as well as health outcomes, including mortality. Their associations with physiological markers of...
We examined properties of culture-level personality traits in ratings of targets (N=5, 109) ages 12 to 17 in 24 cultures. Aggregate scores were generalizable across gender, age, and relationship groups and showed convergence with culture...
Personality traits and cardiorespiratory fitness in older adults are reliable predictors of health and longevity. We examined the association between personality traits and energy expenditure at rest (basal metabolic rate) and during...
Although zinc has been implicated in the functionality of the hippocampus since the 1970's, the recent discovery of adult neuronal stem cells in this region of the brain provides the potential for novel zinc-regulated hippocampal...
BACKGROUND: Many studies have linked depression and obesity; few have more than two assessments of depressive symptoms and adiposity to address the potential bidirectional relationship between adiposity and depressive symptoms from young...
Abstract Objectives. Lower levels of serum brain derived neurotrophic factor (BDNF) is one of the best known biomarkers of depression. To identify genetic variants associated with serum BDNF, we tested the Val66Met (rs6265) functional...
Purpose: The goal of this honors thesis was to investigate the rates of use of prescription drugs during pregnancy and the effect the drugs have on newborn outcomes. Methods: The participants recruited in this study included 1, 507...
Increasing our Library's Value with DALRs The Maguire Medical Library (MML) at the Florida State University has been developing a unique service for faculty and other researchers who need advanced, long-term assistance using a variety of...
Oral naratriptan results in slightly fewer headache days than placebo in patients with menstrual migraines. (SOR A, based on consistent randomized controlled trials [RCTs].) Naproxen and magnesium therapy are also more effective than...
Developing an Academic Medical Library Core Journal Collection in the (Almost) Post-Print Era: The Florida State University College of Medicine Medical Library Experience
The Florida State University (FSU) College of Medicine Medical Library is the first academic medical library to be established since the Web's dramatic appearance during the 1990s. A large customer base for electronic medical information...
BACKGROUND: A key issue for cardiovascular genetic medicine is ascertaining if a putative mutation indeed causes dilated cardiomyopathy (DCM). This is critically important as genetic DCM, usually presenting with advanced, life...
The Florida State University College of Medicine (FSUCOM) has created a new creative arts journal called HEAL: Humanism Evolving through Arts and Literature. This study was designed to evaluate the influence creative arts publications...
AIMS: Investigating the association between personality traits and smoking status using a comprehensive model of personality, the Five-Factor Model (FFM). DESIGN: Cross-sectional survey. Setting Baltimore, MD, USA. Participants Adult...
Nonpharmacologic therapies for phantom limb pain (PLP) that have demonstrated some success include motor imagery therapy (SOR C, extrapolated from a randomized controlled trial [RCT] that enrolled a heterogeneous patient sample);...
Background: Efforts to increase medical student knowledge regarding obesity are needed in medical school curriculum. This article examines a third year medical student intervention utilizing obesity group visits. Description: In our...
Preventing further exposure is clearly important. Postexposure, topical tacrolimus and topical steroids improve symptoms of nickel allergy better than placebo (SOR: B, 2 small RCTs).
Approximately 20% of children in the United States meet criteria for an emotional or behavioral disorder, including internalizing symptoms such as anxiety and depression, and externalizing symptoms such as conduct and oppositional...
It is recommended that pregnant women with Graves' disease and thyroid-stimulating hormone (TSH) antibodies be treated with an antithyroid drug, whereas those without TSH antibodies should simply be observed. Radioiodine treatment with...
National income has a pervasive influence on the perception of ingroup stereotypes, with high status and wealthy targets perceived as more competent. In two studies we investigated the degree to which economic wealth of raters related to...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
