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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Methods of constructing polyolefins having reduced crystallinity using a diimine based catalyst
Description:
The invention is a novel family of polyolefins characterized by chain-walking defects of the type that add extra backbone carbons per monomer. These polyolefins display a large decrease in crystallinity relative to polyolefins known in...
Prion protein based hemin binders and methods of use
Description:
Methods of using portions of the N-terminal domain of prion protein for binding hemin are disclosed. In a particular embodiment, a method comprises administering at least one isolated amino acid sequence comprising a peptide from the...
Modular synthesis of graphene nanoribbons and graphene substructures from oligo-alkynes
Description:
A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.
Polyelectrolyte complex films for analytical and membrane separation of chiral compounds
Description:
The present invention is directed to enantioselective polyelectrolyte complex films. Further, said films may be free or isolated membranes, or coatings on substrates such a porous substrates, capillary tubes, chromatographic packing...
Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency
Description:
Mutants of human FGF-1 are disclosed having increased stability and mitogenic potency. In the FGF-1 polypeptide, primarily residues 12 and 134 are substituted with cysteine, valine or threonine to render the polypeptide more stable and...
Impedance matching in NMR probe with an adjustable segmented transmission line
Description:
Impedance matching between the RF probe and the spectrometer is a standard requirement for NMR probes. Both lumped element and branched transmission line methods are in wide use. Here we propose to use a segmented transmission line...
Hydrophobic fluorinated polyelectrolyte complex films and associated methods
Description:
A fuel cell comprising a proton transporting membrane is provided. The proton transporting membrane comprises a polyelectrolyte film comprising a multilayer comprising an interpenetrating network of a net positively charged...
A process for the preparation of a composition having the formula: in which a compound having the formula: is treated with a base and a silylating agent.
A method for controlling the attachment and growth of cells on a surface of an article, the method comprising contacting the article with living tissue, living organisms, or with water in an aqueous system comprising living organisms...
Reagent for synthesis of para-methoxbenzyl (PMB) ethers and associated methods
Description:
A newly synthesized compound designated lepidine ether 2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB)...
Photo-induced phase transfer of luminescent quantum dots
Description:
A method for the photo-mediated phase transfer of inorganic nanocrystals, such as luminescent quantum dots, QDs, is provided. Irradiation, specifically UV excitation (λex<400 nm), promotes the in-situ ligand exchange of hydrophobic...
Antibody biomarker specific for mitotic cells and related methods
Description:
An isolated antibody having a specific binding affinity for a polypeptide comprising the amino acid sequence HTEGKP (SEQ ID NO: 2) phosphorylated at threonine is described. The antibody may be used as biomarker for mitotic cells. A...
A method for determining a replication timing footprint comprises the following steps: (a) selecting a set of chosen regions of the replication timing profile of a chromosome of an individual, (b) choosing a set of selected regions from...
RNAi therapeutic for treatment of hepatitis C infection
Description:
Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that specifically target human cyclophilin A (CyPA) to effectively inhibit Hepatitis C (HCV) infection in a cell. Such siRNA and...
Fibroblast growth factor mutants having improved functional half-life and methods of their use
Description:
Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino...
Optoelectronic switch having a photovoltaic response and associated method of use
Description:
A light-induced diode-like response in multi-layered MoSe2 field-effect transistors resulting from a difference in the size of the Schottky barriers between drain and source contacts, wherein each barrier can be modeled as a Schottky...
A process for the preparation of a compound having the formula: the process comprising treating a compound having the formula: with an alkyl metal species or with a Lewis acid in the presence of a tertiary amine base, wherein P2 is...
A cable termination comprising an upper cryostat chamber containing a liquid cryogen and a lower cryostat chamber containing a gaseous cryogen to maintain dielectric integrity and thermal management of an electric connection. A gaseous...
Method for small-signal stability assessment of power systems using source side and load side perturbations
Description:
A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based...
Fire retardant materials arc provided that contain carbon nanotubes and particles capable of endothermically reacting when exposed to elevated temperatures. The carbon nanotubes may be a buckypaper. Methods also are provided for making a...
Superconductive alloys having bifurcated critical current density and method of preparation
Description:
A device having superconductive and resistive states including an element comprising a high temperature superconductive material having a first (high) state with a first (high) critical current density and having a second (low) state...
System for locating a fault in a power distribution system comprising at least one DC voltage distributed resource having a controllable voltage source converter
Description:
The present invention provides a system to ensure that distributed resources of a power distribution system remain connected to the circuitry of the power distribution system when a fault occurs at a distributed resource node to assist...
C-lysine conjugates as pH-controlled, light-activated reagents for double stranded DNA cleavage and associated methods
Description:
Compounds and methods for double-stranded DNA cleavage of light-activated lysine conjugates are enhanced at the slightly acidic pH suitable for selective targeting of cancer cells by the presence of two amino groups of different...
Resin infusion between double flexible tooling system
Description:
A resin infusion system uses a housing that has an upper flexible diaphragm and a lower flexible diaphragm such that the two diaphragms form a cavity. A fiber reinforcement mat is positioned within the cavity. A mold is positioned below...
A method is provided for producing crystalline nanoparticle semiconductor material. The method includes the steps of mixing a precursor in a solvent to form a reaction mixture and subjecting the reaction mixture to microwave dielectric...
Ordered array of magnetized nanorods and associated methods
Description:
An ordered array of magnetized nanorods includes a plurality of metallic nanorods generally cylindrical in shape and including a nickel portion coated with a positively charged polyelectrolyte and a gold portion coated with an...
System for continuous magnetic separation of components from a mixture
Description:
A magnetic system and apparatus having a multi-dimensional gradient for continuous, on-line separation of components from a mixture of chemical entities which comprises at least one separation chamber with a plurality of channels and a...
Light-weight vacuum chamber and applications thereof
Description:
A vacuum chamber with an innovative wall structure. Instead of a conventional homogenous wall structure, the invention uses an array of internally-pressurized, thin-walled cells to contain an enclosed volume. The walls are arranged so...
A method of using one or more microjets to create and/or control oblique shock waves. The introduction of microjet flow into a supersonic stream creates an oblique shock wave. This wave can be strengthened—by increasing microjet...
Materials and methods for cryopreserved bone constructs
Description:
Porous HCG scaffolds are provided in a perfusion bioreactor. Cells are seeded in the HCG scaffolds and cell culture media is perfused through the bioreactor to allow for cell seeding and growth. The cell culture media is removed, the HCG...
The present invention provides a catalyst complex or ligand, and compositions thereof, for use in a variety of organic reactions having high reactivity and enantioselectivity. The catalyst is a N-heterocyclic carbene having three fused...
Method of producing cobalt-platinum magnetic alloys with improved magnetic properties
Description:
A method for processing CoPt alloys with improved magnetic properties. The method includes sealing a sample of a CoPt alloy in an evacuated quartz tube, and heating the alloy to a temperature of approximately 1000 degrees C. to...
Formulation and method for improved ion exchange in zeolites and related aluminosilicates using polymer solutions
Description:
Among other things, this disclosure provides a method for exchanging cations in an aluminosilicate. The method includes combining, in an exchange solvent and under ion exchange conditions, an ion-exchangeable aluminosilicate having a...
Cryogenic heat sink for gas cooled superconducting power devices
Description:
A heat sink and method for gaseous cooling of superconducting power devices. Heat sink is formed of a solid material of high thermal conductivity and attached to the area needed to be cooled. Two channels are connected to the heat sink...
Traceless directing groups in radical cascades: from oligoalkynes to fused helicenes without tethered initators
Description:
The present disclosure is directed to a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by a propargyl alkoxy moiety. Radical translocations lead...
Stable iron oxide nanoparticles and method of production
Description:
A method of preparing a dispersion of stabilized iron oxide nanoparticles that comprise cores and coatings on the cores, which comprise zwitterionic functional groups chemically bound to the cores, using a single solution that comprises...
Class of non-stimulant treatment and ADHD and related disorders
Description:
Described is a method of administering nor-binaltorphimine (nor-BNI) or a nor-BNI analog to an individual having Attention Deficit/Hyperactivity Disorder (ADHD) to thereby reduce the effects of ADHD in the individual.
NMR probe coils designed to operate at two different frequencies, producing a strong and homogenous magnetic field at both the frequencies. This single coil, placed close to the sample, provides a method to optimize the NMR detection...
Enhanced flux pinning in superconductors by embedding carbon nanotubes with BSCCO materials
Description:
Enhanced flux pinning in superconductors is achieved by embedding carbon nanotubes into a superconducting matrix. The carbon nanotubes simulate the structure, size and shape of heavy ion induced columnar defects in a superconductor such...
Magnetic shimming configuration with optimized turn geometry and electrical circuitry
Description:
A magnetic shimming configuration for a high-field magnet having optimized turn geometry and electrical circuitry. The present invention accomplishes this by combining the corrective functionalities of the standard X and ZX shims into...
Analytical method for protein mapping using hydrogen/deuterium exchange
Description:
Analytical methods using hydrogen/deuterium exchange are provided which reduce or eliminate the back-exchange of deuterium for hydrogen. The methods, which are useful in protein and peptide mapping, include the steps of (a) providing a...
Polyethylene glycol based oligomers for coating nanoparticles, nanoparticles coated therewith, and related methods
Description:
In a composition aspect of the invention, a nanoparticle coating comprises repeating polyacrylic acid monomers covalently bound together to form an aliphatic chain having a plurality of carboxylic acid functional groups and modified...
Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis
Description:
A process for benzylating an alcohol includes mixing 2-benzyloxy-1-methylpyridinium triflate in an aromatic hydrocarbon solvent having a predetermined boiling point; adding an acid scavenger to the mixture; combining the alcohol to be...
Species-specific DNA probes for vibrio cholerae and methods
Description:
The present invention relates to species-specific DNA probes specific for Vibrio vulnificus and Vibrio cholerae. The DNA probes of the present invention specifically detects Vibrio vulnificus or Vibrio cholerae in a mixed bacterial...
System and methods for implementing a non-linear electrical circuit dynamic fuel cell model
Description:
A nonlinear electrical circuit dynamic model for different fuel cells is provided. The model provides a nonlinear electrical circuit equivalent, the parameters of which correspond to the particular fuel cell being modeled. The parameters...
Analytical separations with polyelectrolyte layers, molecular micelles, or zwitterionic polymers
Description:
Polymeric surfactants (molecular micelles) are disclosed for use in open tubular capillary electrochromatography or in high performance liquid chromatography. For example, fused silica capillaries are coated with thin films of charged...
The present invention provides processes for the production of paclitaxel. Paclitaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7, 10-protected...
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