Effects of Cardiovascular Health on Cognitive Function and Driving Performance among Healthy Older Adults

Aging is associated with a decline in cognitive and psychomotor functions, resulting in difficulties with daily activities such as driving. Cognitive function has been found to be associated with arterial stiffening. These age-related decrements can be mitigated through routine aerobic exercise. To determine the effects of life-long aerobic exercise on cognitive function, driving performance, and cardiovascular health (i.e., arterial stiffness and thickness) among older adults (65 – 84 years old). A cross-sectional design was utilized to compare 27 endurance-trained older adults with 35 sedentary counterparts. Driving performance and cognitive function were measured via driving simulator and a cognitive battery, respectively. Cardiovascular health was assessed via a perceptually-regulated exercise test, carotid-intima media thickness (IMT) via Doppler ultrasound, and carotid-femoral pulse wave velocity (cf-PWV). Fitness comparisons were made using an independent sample t-test. Cognitive function and driving performance scores were transformed to Z-scores. VO2max was higher in the endurance-trained group compared to the sedentary group (41±9 vs 25±3 ml/kg/min, p<.01). There were no differences between the groups in cf-PWV (12±2 vs. 12±2 m/s), carotid-IMT (.74±.15 vs .76±.13 mm), nor cognitive function scores (-.01±.57 vs -.09±.97). However, the endurance-trained group performed better on the driving simulator (.18±.58 vs -.28±.92, p<.05). Enhanced cardiorespiratory fitness may mitigate age-related decrements to driving performance.