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Shah, S., & Rodríguez, J. (2010). How Are Thyroid Function Tests Altered by Thyroid Replacement Medications? Evidence Based Practice. Retrieved from http://purl.flvc.org/fsu/fd/FSU_migr_fmr-0032
Small changes in the dosing of levothyroxine (±25 mcg) are associated with large changes in serum thyroid-stimulating hormone (TSH) and free thyroxine (FT4) concentrations, but not with measurable changes in hypothyroid symptoms, well-being, or quality of life. (SOR: B, based on a single RCT.) Taking levothyroxine while fasting is associated with a higher serum FT4 and lower serum TSH compared with administration after a meal, but these differences are small. (SOR: C, based on a single RCT using disease-oriented outcomes.)
thyroid replacement medications, levothyroxine, thyroid function tests
Identifier
FSU_migr_fmr-0032
Language
English
Shah, S., & Rodríguez, J. (2010). How Are Thyroid Function Tests Altered by Thyroid Replacement Medications? Evidence Based Practice. Retrieved from http://purl.flvc.org/fsu/fd/FSU_migr_fmr-0032