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Heteroaryl substituted oxazinone compounds for the preparation of taxol. (1996). Heteroaryl substituted oxazinone compounds for the preparation of taxol. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5532363
Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R.sub.1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR.sub.7 wherein R.sub.7 is alkyl, alkenyl, alkynyl, aryl or heteroaryl; R.sub.2 and R.sub.5 are independently selected from hydrogen, alkyl alkenyl, alkynyl, aryl, heteroaryl, and OR.sub.8 wherein R.sub.8 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, or hydroxyl protecting group; and R.sub.3 and R.sub.6 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, aryl and heteroaryl.
Heteroaryl substituted oxazinone compounds for the preparation of taxol. (1996). Heteroaryl substituted oxazinone compounds for the preparation of taxol. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5532363
