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Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. (1993). Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5227400
A taxane derivative of the formula ##STR1## wherein ##STR2## Z is --OT.sub.1, T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2, PA0 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl, C.sub.1 -C.sub.6 alkynyl or monocylic aryl, PA0 R.sub.3 is benzoyl, substituted benzoyl or C.sub.1 -C.sub.6 alkoxycarbonyl, PA0 Ac is acetyl, and PA0 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. (1993). Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5227400
