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Hurricane Sandy (2012) had one of the greatest economic impacts of any hurricane in United States history. However, its broader scientific impacts, especially its impacts on the chemistry of the upper troposphere and lower stratosphere, have not been documented. This study uses the Weather Research and Forecasting with Chemistry model (WRF-Chem), run at a convective-permitting resolution, to examine the transport of pollutants inside Hurricane Sandy as it made landfall along the Eastern Seaboard. Although several pollutants were examined, the concentrations of CO throughout the atmosphere and the transport of CO from sources along the coast in Hurricane Sandy's convective region were primary focus. A forward-trajectory analysis also was performed using the high-resolution WRF-Chem data as input to the Hybrid Single Particle Lagrangian Integrated Trajectory Model (HYSPLIT). The results of this high-resolution chemical and meteorological simulation will be presented with a focus on transport to the upper troposphere and lower stratosphere. To our knowledge, such high-resolution chemical and meteorological simulations of tropical cyclones have not been reported in the previous literature.