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In patients with peripheral vascular disease (PVD), a structured exercise program improves walking distances and is relatively low risk and low cost. Lipid-lowering therapy reduces the risk of cardiovascular events and also increases walking distances. Cilostazol and naftidrofuryl improve walking distance, but add an additional expense. Angioplasty appears to improve walking distance better than exercise at 6 months, but not at 2 or 6 years. (SOR A, based on a systematic reviews.)