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The purpose of this single case multiple-baseline design was to investigate the utility of using a mobile device application specifically Pictello for the iPad, as a tool to teach and support peer buddies to interact with a student with autism spectrum disorder (ASD). Peer-mediated interventions have been highly successful in improving the social skills of children who have autism spectrum disorder (ASD). However, the high level of support required to implement these interventions is not feasible for many teachers. This study explored the use of technology to support peers' use of communication facilitation strategies, thereby saving teachers' time and increasing opportunities for intervention. Intervention was conducted within the context of peer buddy interactions during typical school activities. Results demonstrated increased responses, initiations and topic maintenance of the target child during the intervention period. This research contributes to the literature on peer-mediated intervention through integrating evidence-based practice and technology to increase feasibility and accessibility to classroom teachers and other school-based professionals.