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Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis.
Dpb11 protein helps control assembly of the Cdc45·Mcm2-7·GINS replication fork helicase.
Excess histone levels mediate cytotoxicity via multiple mechanisms.
Fin1-PP1 Helps Clear Spindle Assembly Checkpoint Protein Bub1 from Kinetochores in Anaphase.
Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.
Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A.
molecular function of the yeast polo-like kinase Cdc5 in Cdc14 release during early anaphase.
replication initiation protein Sld2 regulates helicase assembly.
signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment.
function and regulation of budding yeast Swe1 in response to interrupted DNA synthesis.
Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae.
Replicative stress induces intragenic transcription of the ASE1 gene that negatively regulates Ase1 activity.
Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase.
Coordination of chromatid separation and spindle elongation by antagonistic activities of mitotic and S-phase CDKs.
Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.
DNA damage checkpoints inhibit mitotic exit by two different mechanisms.