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Compositions and methods for inhibiting collagen production
Protein controlling synthesis of collagen and associated methods
Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen
LARP6 Meets Collagen mRNA
LARP6 Meets Collagen mRNA
La-related protein 6 controls ciliated cell differentiation.
Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis.
Nonmuscle myosin-dependent synthesis of type I collagen.
Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo.
Role of cytokine receptor-like factor 1 in hepatic stellate cells and fibrosis.
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs.
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis.
novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.
mTORC1 phosphorylates LARP6 to stimulate type I collagen expression.
novel role of vimentin filaments
Discovery and evaluation of inhibitor of LARP6 as specific antifibrotic compound
BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left-right patterning.
Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.
RFX7 is required for the formation of cilia in the neural tube.
RNA protein interactions governing expression of the most abundant protein in human body, type I collagen.
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis.