Current Search: Research Repository (x) » * (x) » Citation (x) » Askew, A. (x) » Holton, Robert A. (x) » Rengan, Kasthuri (x)
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Title
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Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them.
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Creator
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Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri
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Abstract/Description
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Taxane derivatives of the formula ##STR1## wherein R.sub.1 is phenyl or p-nitrophenyl, PA1 R.sub.3 is furyl or thienyl, PA1 T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2, PA1 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl or monocylic aryl, PA1 Ac is acetyl, and PA1 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor...
Show moreTaxane derivatives of the formula ##STR1## wherein R.sub.1 is phenyl or p-nitrophenyl, PA1 R.sub.3 is furyl or thienyl, PA1 T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2, PA1 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl or monocylic aryl, PA1 Ac is acetyl, and PA1 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
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Date Issued
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1994-02-01
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Identifier
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FSU_uspto_5283253, 5283253, 711524, 07/975723, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Pyridyl substituted B-lactam compounds.
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Creator
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Holton, Robert A., Rengan, Kasthuri
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Abstract/Description
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Pyridyl substituted .beta.-lactam compounds used in preparing taxane derivatives having a 3' pyridyl substituted C13 side chain.
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Date Issued
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1998-06-02
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Identifier
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FSU_uspto_5760219, 5760219, 711524, 08/717136, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them.
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Creator
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Suzuki, Yukio, Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin, Chai, Ki-byung, Idmoumaz, Hamid
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Abstract/Description
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Taxane derivatives having an alkoxy, alkenoxy or aryloxy substituted C13 side chain.
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Date Issued
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2000-01-25
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Identifier
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FSU_uspto_6018073, 6018073, 187776, 08/991963, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them.
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Creator
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Suzuki, Yukio, Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin, Chai, Ki-byung, Idmoumaz, Hamid
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Abstract/Description
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Taxane derivatives having an alkoxy, alkenoxy or aryloxy substituted C13 side chain.
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Date Issued
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1998-04-14
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Identifier
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FSU_uspto_5739362, 5739362, 187776, 08/461103, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them.
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Creator
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Suzuki, Yukio, Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin, Chai, Ki-byung, Idmoumaz, Hamid
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Abstract/Description
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Taxane derivatives having an alkoxy, alkenoxy or aryloxy substituted C13 side chain.
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Date Issued
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2004-09-21
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Identifier
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FSU_uspto_6794523, 6794523, 187776, 10/245167, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them.
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Creator
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Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin
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Abstract/Description
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Taxane derivatives having an amino substituted C13 side chain.
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Date Issued
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1998-01-20
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Identifier
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FSU_uspto_5710287, 5710287, 711524, 08/462122, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them.
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Creator
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Holton, Robert A., Rengan, Kasthuri
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Abstract/Description
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Taxane derivatives having a 3' pyridyl substituted C13 side chain.
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Date Issued
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1996-02-06
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Identifier
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FSU_uspto_5489601, 5489601, 711524, 08/095085, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Carbamoyl substituted &bgr;-lactams.
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Creator
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Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin
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Abstract/Description
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Taxane derivatives having an amino substituted C13 side chain.
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Date Issued
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2004-05-04
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Identifier
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FSU_uspto_6730782, 6730782, 711524, 10/082755, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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C13 amido substituted taxane derivatives and pharmaceutical compositions containing them.
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Creator
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Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin
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Abstract/Description
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Taxane derivatives having an amino substituted C13 side chain.
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Date Issued
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2002-04-09
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Identifier
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FSU_uspto_6369244, 6369244, 711524, 09/523535, 600b83161da1122888348587dc18798c
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Format
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Citation
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Title
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Amino substituted taxanes.
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Creator
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Holton, Robert A., Nadizadeh, Hossain, Rengan, Kasthuri, Tao, Chunlin
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Abstract/Description
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Taxane derivatives having an amino substituted C13 side chain.
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Date Issued
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2000-04-18
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Identifier
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FSU_uspto_6051724, 6051724, 711524, 08/953889, 600b83161da1122888348587dc18798c
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Format
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Citation
