Search results

Title: Suicidality prospectively predicts greater urges to smoke following a cessation attempt: Mediation through perceived barriers to cessation..
Creator: Albanese, Brian J, Allan, Nicholas P, Boffa, Joseph W, Chavarria, Jesus, Raines, Amanda M, Zvolensky, Michael J, Schmidt, Norman B
Abstract/Description: Growing interest in developing more effective smoking cessation treatments has facilitated the need to further investigate cognitive-affective factors that inhibit successful smoking cessation, such as urges to smoke. Research has strongly supported an association between suicidality and smoking, yet no work has investigated whether suicidality may increase urges to smoke. The current study sought to evaluate the impact of suicidality on smoking-related cognitive-affective factors predictive...
Show moreGrowing interest in developing more effective smoking cessation treatments has facilitated the need to further investigate cognitive-affective factors that inhibit successful smoking cessation, such as urges to smoke. Research has strongly supported an association between suicidality and smoking, yet no work has investigated whether suicidality may increase urges to smoke. The current study sought to evaluate the impact of suicidality on smoking-related cognitive-affective factors predictive of smoking relapse among a community sample of 209 daily smokers engaged in a smoking cessation program. Structural equation modeling (SEM) was used to test the effects of self-reported pre-cessation suicidality on urges to smoke 1 month post-cessation as well as whether this effect was mediated by greater barriers to cessation. Results indicated that internal barriers to cessation significantly mediated the effect of pre-cessation suicidality on greater urges to smoke 1 month following smoking cessation attempt. These findings suggest that elevated suicidality may affect perceived internal barriers to cessation and subsequently urges to smoke 1 month following a quit attempt.
Show less
Date Issued: 2016-01-15
Identifier: FSU_pmch_26519643, 10.1016/j.jad.2015.10.015, PMC4750401, 26519643, 26519643, S0165-0327(15)30232-9
Format: Citation

Title: A preliminary evaluation of the validity of binge-eating disorder defining features in a community-based sample.
Creator: Klein, Kelly M, Forney, K Jean, Keel, Pamela K
Abstract/Description: Little empirical attention has been paid to the DSM-5 definition of binge-eating disorder (BED), particularly to the associated features of binge episodes. The present study sought to determine how the associated features and undue influence of weight/shape on self-evaluation contribute to evidence of a clinically significant eating disorder. Secondary analyses were conducted on data (N = 80; 76.3% women, 76.3% Caucasian, ages 18-43) collected through an epidemiological study of eating...
Show moreLittle empirical attention has been paid to the DSM-5 definition of binge-eating disorder (BED), particularly to the associated features of binge episodes. The present study sought to determine how the associated features and undue influence of weight/shape on self-evaluation contribute to evidence of a clinically significant eating disorder. Secondary analyses were conducted on data (N = 80; 76.3% women, 76.3% Caucasian, ages 18-43) collected through an epidemiological study of eating patterns. Descriptive statistics were used to report the sample prevalence of the features, independently and in combination. Correlations and alpha reliability were employed to examine relationships among associated features, distress regarding bingeing, and clinical diagnosis. Regression models and receiver-operating characteristic (ROC) curves were used to determine the utility of the features for explaining variance in distress. Internal consistency reliability for indicators was low, and several features demonstrated low or nonsignificant associations with distress and diagnosis. Feeling disgusted/depressed/guilty was the only unique predictor of distress (p = 0.001). For the ROC curves, three features was the best threshold for predicting distress. Results support the need to refine the features to ensure better detection of clinically significant eating pathology for research inclusion and treatment of the illness. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:524-528).
Show less
Date Issued: 2016-05-01
Identifier: FSU_pmch_26607858, 10.1002/eat.22479, PMC4870096, 26607858, 26607858
Format: Citation

Title: Smoking-Specific Experiential Avoidance is Indirectly Associated with Trait Worry and Smoking Processes among Treatment-Seeking Smokers.
Creator: Farris, Samantha G, Zvolensky, Michael J, Norton, Peter J, Hogan, Julianna, Smith, Angela H, Talkovsky, Alexander M, Garey, Lorra, Schmidt, Norman B
Abstract/Description: Limited work has examined worry, or apprehensive anticipation about future negative events, in terms of smoking. One potential explanatory factor is the tendency to respond inflexibly and with avoidance in the presence of smoking-related distress (smoking-specific experiential avoidance). Participants (n = 465) were treatment-seeking daily smokers. Cross-sectional (pre-treatment) self-report data were utilized to assess trait worry, smoking-specific experiential avoidance, and four smoking...
Show moreLimited work has examined worry, or apprehensive anticipation about future negative events, in terms of smoking. One potential explanatory factor is the tendency to respond inflexibly and with avoidance in the presence of smoking-related distress (smoking-specific experiential avoidance). Participants (n = 465) were treatment-seeking daily smokers. Cross-sectional (pre-treatment) self-report data were utilized to assess trait worry, smoking-specific experiential avoidance, and four smoking criterion variables: nicotine dependence, motivational aspects of quitting, perceived barriers to smoking cessation, and severity of problematic symptoms reported in past quit attempts. Trait worry was significantly associated with greater levels of nicotine dependence, motivation to quit smoking, perceived barriers for smoking cessation, and more severe problems while quitting in the past; associations occurred indirectly through higher levels of smoking-specific experiential avoidance. Findings provide initial support for the potential role of smoking-specific experiential avoidance in explaining the association between trait worry and a variety of smoking processes.
Show less
Date Issued: 2016-10-01
Identifier: FSU_pmch_25398072, 10.1080/08964289.2014.984650, PMC5025255, 25398072, 25398072
Format: Citation

Title: Longitudinal Associations Among Relationship Satisfaction, Sexual Satisfaction, and Frequency of Sex in Early Marriage.
Creator: McNulty, James K, Wenner, Carolyn A, Fisher, Terri D
Abstract/Description: The current research used two 8-wave longitudinal studies spanning the first 4-5 years of 207 marriages to examine the potential bidirectional associations among marital satisfaction, sexual satisfaction, and frequency of sex. All three variables declined over time, though the rate of decline in each variable became increasingly less steep. Controlling for these changes, own marital and sexual satisfaction were bidirectionally positively associated with one another; higher levels of marital...
Show moreThe current research used two 8-wave longitudinal studies spanning the first 4-5 years of 207 marriages to examine the potential bidirectional associations among marital satisfaction, sexual satisfaction, and frequency of sex. All three variables declined over time, though the rate of decline in each variable became increasingly less steep. Controlling for these changes, own marital and sexual satisfaction were bidirectionally positively associated with one another; higher levels of marital satisfaction at one wave of assessment predicted more positive changes in sexual satisfaction from that assessment to the next and higher levels of sexual satisfaction at one wave of assessment predicted more positive changes in marital satisfaction from that assessment to the next. Likewise, own sexual satisfaction and frequency of sex were bidirectionally positively associated with one another. Additionally, partner sexual satisfaction positively predicted changes in frequency of sex and own sexual satisfaction among husbands, yet partner marital satisfaction negatively predicted changes in both frequency of sex and own sexual satisfaction. Controlling these associations, marital satisfaction did not directly predict changes in frequency of sex or vice versa. Only the association between partner sexual satisfaction and changes in own sexual satisfaction varied across men and women and none of the key effects varied across the studies. These findings suggest that sexual and relationship satisfaction are intricately intertwined and thus that interventions to treat and prevent marital distress may benefit by targeting the sexual relationship and interventions to treat and prevent sexual distress in marriage may benefit by targeting the marital relationship.
Show less
Date Issued: 2016-01-01
Identifier: FSU_pmch_25518817, 10.1007/s10508-014-0444-6, PMC4472635, 25518817, 25518817, 10.1007/s10508-014-0444-6
Format: Citation

Title: Neurobehavioral Traits as Transdiagnostic Predictors of Clinical Problems.
Creator: Nelson, Lindsay D, Strickland, Casey, Krueger, Robert F, Arbisi, Paul A, Patrick, Christopher J
Abstract/Description: The National Institute of Mental Health Research Domain Criteria initiative (Insel et al., 2010) calls for a focus on biologically meaningful dimensional constructs in the study of clinical problems. Examples are needed of how Research Domain Criteria constructs can be linked to clinical problems. We examined how two such constructs, threat sensitivity (THT+) and weak inhibitory control (INH-), operationalized using scale measures of fear/fearlessness and inhibition/disinhibition dimensions...
Show moreThe National Institute of Mental Health Research Domain Criteria initiative (Insel et al., 2010) calls for a focus on biologically meaningful dimensional constructs in the study of clinical problems. Examples are needed of how Research Domain Criteria constructs can be linked to clinical problems. We examined how two such constructs, threat sensitivity (THT+) and weak inhibitory control (INH-), operationalized using scale measures of fear/fearlessness and inhibition/disinhibition dimensions from established structural models, predicted symptoms of multiple Diagnostic and Statistical Manual of Mental Disorders (4th edition) clinical disorders in 471 community adults. Robust relationships with internalizing disorder symptoms were evident for both trait variables, with THT+ more predictive of fear disorder symptoms and INH- more predictive of distress disorder symptoms. For substance-related problems, prediction was evident only for INH-. Additionally, interactive effects of THT+ and INH- were found for distress disorders, and to a lesser extent, fear disorders. Given their well-established physiological correlates, these dispositional variables represent prime targets for combined psychometric-neurophysiological assessment of broad liabilities to multiple forms of psychopathology.
Show less
Date Issued: 2016-02-01
Identifier: FSU_pmch_25657306, 10.1177/1073191115570110, PMC4881426, 25657306, 25657306, 1073191115570110
Format: Citation

Title: The Association between Sleep Disturbances and Depression among Firefighters: Emotion Dysregulation as an Explanatory Factor..
Creator: Hom, Melanie A, Stanley, Ian H, Rogers, Megan L, Tzoneva, Mirela, Bernert, Rebecca A, Joiner, Thomas E
Abstract/Description: To investigate emotion regulation difficulties in association with self-reported insomnia symptoms, nightmares, and depression symptoms in a sample of current and retired firefighters. A total of 880 current and retired United States firefighters completed a web-based survey of firefighter behavioral health. Self-report measures included the Center for Epidemiologic Studies Depression Scale, Insomnia Severity Index, PTSD Checklist, and Difficulties in Emotion Regulation Scale. A notable...
Show moreTo investigate emotion regulation difficulties in association with self-reported insomnia symptoms, nightmares, and depression symptoms in a sample of current and retired firefighters. A total of 880 current and retired United States firefighters completed a web-based survey of firefighter behavioral health. Self-report measures included the Center for Epidemiologic Studies Depression Scale, Insomnia Severity Index, PTSD Checklist, and Difficulties in Emotion Regulation Scale. A notable portion of participants reported clinically significant depression symptoms (39.6%) and insomnia symptoms (52.7%), as well as nightmare problems (19.2%), each of which demonstrated a strong association with emotion regulation difficulties (rs = 0.56-0.80). Bootstrapped mediation analyses revealed that the indirect effects of overall emotion regulation difficulties were significant both for the relationship between insomnia and depression (95% CI: 0.385-0.566) and nightmares and depression (95% CI: 1.445-2.365). Limited access to emotion regulation strategies emerged as the strongest, significant indirect effect for both relationships (insomnia 95% CI: 0.136-0.335; nightmares 95% CI: 0.887-1.931). Findings extend previous affective neuroscience research by providing evidence that insomnia and nightmares may influence depression symptoms specifically through the pathway of explicit emotion regulation difficulties. Sleep disturbances may impair the ability to access and leverage emotion regulation strategies effectively, thus conferring risk for negative affect and depression.
Show less
Date Issued: 2016-02-01
Identifier: FSU_pmch_26350604, 10.5664/jcsm.5492, PMC4751428, 26350604, 26350604, jc-00300-15
Format: Citation

Title: Is childhood trauma associated with lifetime suicide attempts in women with bulimia nervosa?.
Creator: Smith, Christina E, Pisetsky, Emily M, Wonderlich, Stephen A, Crosby, Ross D, Mitchell, James E, Joiner, Thomas E, Bardone-Cone, Anna, Le Grange, Daniel, Klein, Marjorie H, Crow...
Show moreSmith, Christina E, Pisetsky, Emily M, Wonderlich, Stephen A, Crosby, Ross D, Mitchell, James E, Joiner, Thomas E, Bardone-Cone, Anna, Le Grange, Daniel, Klein, Marjorie H, Crow, Scott J, Peterson, Carol B
Show less
Abstract/Description: The purpose of this study was to explore the association between specific forms of childhood abuse and neglect with lifetime suicide attempts in women with bulimia nervosa (BN). Two hundred and four women aged 18-65 (mean 25.6 years, SD 9.13) with full or subclinical BN were recruited in five US Midwestern communities and specialized eating disorder clinics. Participants completed questionnaires including the Childhood Trauma Questionnaire (CTQ) and self-reported whether they had ever had a...
Show moreThe purpose of this study was to explore the association between specific forms of childhood abuse and neglect with lifetime suicide attempts in women with bulimia nervosa (BN). Two hundred and four women aged 18-65 (mean 25.6 years, SD 9.13) with full or subclinical BN were recruited in five US Midwestern communities and specialized eating disorder clinics. Participants completed questionnaires including the Childhood Trauma Questionnaire (CTQ) and self-reported whether they had ever had a lifetime suicide attempt. Logistic regression analyses were used to predict lifetime suicide attempts from each subscale of the CTQ. Childhood emotional, physical, and sexual abuse were significantly associated with the presence of a lifetime suicide attempt in women with BN. Childhood emotional and physical neglect were not associated with suicide attempts. Individuals with BN who have experienced childhood emotional and sexual abuse are at increased risk of a lifetime suicide attempt. Future research is needed to understand the mechanism to address in treatment and prevention efforts. It is important for clinicians to be aware of the potential increased risk of suicide in individuals with BN with a history of childhood abuse.
Show less
Date Issued: 2016-06-01
Identifier: FSU_pmch_26462683, 10.1007/s40519-015-0226-8, PMC4833682, 26462683, 26462683, 10.1007/s40519-015-0226-8
Format: Citation

Title: An update on the Florida State Twin Registry.
Creator: Taylor, Jeanette E, Hart, Sara A, Mikolajewski, Amy J, Schatschneider, Christopher
Abstract/Description: The Florida State Twin Registry began in 2002 through a pilot study of personality disorders and executive cognitive functioning in adult twins. Since 2006, the registry has grown substantially as part of the Learning Disability Research Center at Florida State University that recently began its second funding cycle through the National Institute of Child Health and Development. An update on the Florida State Twin Registry sample, focus, and measures is provided, as well as future directions.
Date Issued: 2013-02-01
Identifier: FSU_pmch_23067863, 10.1017/thg.2012.74, PMC3570689, 23067863, 23067863, S1832427412000746
Format: Citation

Title: Distinct Regions within Medial Prefrontal Cortex Process Pain and Cognition.
Creator: Jahn, Andrew, Nee, Derek Evan, Alexander, William H, Brown, Joshua W
Abstract/Description: Neuroimaging studies of the medial prefrontal cortex (mPFC) suggest that the dorsal anterior cingulate cortex (dACC) region is responsive to a wide variety of stimuli and psychological states, such as pain, cognitive control, and prediction error (PE). In contrast, a recent meta-analysis argues that the dACC is selective for pain, whereas the supplementary motor area (SMA) and pre-SMA are specifically associated with higher-level cognitive processes (Lieberman and Eisenberger, 2015). To...
Show moreNeuroimaging studies of the medial prefrontal cortex (mPFC) suggest that the dorsal anterior cingulate cortex (dACC) region is responsive to a wide variety of stimuli and psychological states, such as pain, cognitive control, and prediction error (PE). In contrast, a recent meta-analysis argues that the dACC is selective for pain, whereas the supplementary motor area (SMA) and pre-SMA are specifically associated with higher-level cognitive processes (Lieberman and Eisenberger, 2015). To empirically test this claim, we manipulated effects of pain, conflict, and PE in a single experiment using human subjects. We observed a robust dorsal-ventral dissociation within the mPFC with cognitive effects of PE and conflict overlapping dorsally and pain localized more ventrally. Classification of subjects based on the presence or absence of a paracingulate sulcus showed that PE effects extended across the dorsal area of the dACC and into the pre-SMA. These results begin to resolve recent controversies by showing the following: (1) the mPFC includes dissociable regions for pain and cognitive processing; and (2) meta-analyses are correct in localizing cognitive effects to the dACC, although these effects extend to the pre-SMA as well. These results both provide evidence distinguishing between different theories of mPFC function and highlight the importance of taking individual anatomical variability into account when conducting empirical studies of the mPFC. Decades of neuroimaging research have shown the mPFC to represent a wide variety of stimulus processing and cognitive states. However, recently it has been argued whether distinct regions of the mPFC separately process pain and cognitive phenomena. To address this controversy, this study directly compared pain and cognitive processes within subjects. We found a double dissociation within the mPFC with pain localized ventral to the cingulate sulcus and cognitive effects localized more dorsally within the dACC and spreading into the pre-supplementary motor area. This provides empirical evidence to help resolve the current debate about the functional architecture of the mPFC.
Show less
Date Issued: 2016-12-07
Identifier: FSU_pmch_27807031, 10.1523/JNEUROSCI.2180-16.2016, PMC5148227, 27807031, 27807031, JNEUROSCI.2180-16.2016
Format: Citation

Title: Weight suppression predicts bulimic symptoms at 20-year follow-up: The mediating role of drive for thinness..
Creator: Bodell, Lindsay P, Brown, Tiffany A, Keel, Pamela K
Abstract/Description: Weight suppression predicts the onset and maintenance of bulimic syndromes. Despite this finding, no study has examined psychological mechanisms contributing to these associations using a longitudinal design. Given societal pressures to be thin and an actual history of higher weight, it is possible that greater weight suppression contributes to increased fear of gaining weight and preoccupation with being thin, which increase vulnerability to eating disorders. The present study investigated...
Show moreWeight suppression predicts the onset and maintenance of bulimic syndromes. Despite this finding, no study has examined psychological mechanisms contributing to these associations using a longitudinal design. Given societal pressures to be thin and an actual history of higher weight, it is possible that greater weight suppression contributes to increased fear of gaining weight and preoccupation with being thin, which increase vulnerability to eating disorders. The present study investigated whether greater drive for thinness mediates associations between weight suppression and bulimic symptoms over long-term follow-up. Participants were women (n = 1,190) and men (n = 509) who completed self-report surveys in college and 10- and 20-years later. Higher weight suppression at baseline predicted higher bulimic symptoms at 20-year follow-up (p < .001), while accounting for demographic variables and baseline bulimic symptoms, body mass index, and drive for thinness. Increased drive for thinness at 10-year follow-up mediated this effect. Findings highlight the long-lasting effect of weight suppression on bulimic symptoms and suggest that preoccupation with thinness may help maintain this association. Future studies would benefit from incorporating other hypothesized consequences of weight suppression, including biological factors, into risk models. (PsycINFO Database Record
Show less
Date Issued: 2017-01-01
Identifier: FSU_pmch_27808544, 10.1037/abn0000217, PMC5215971, 27808544, 27808544, 2016-53088-001
Format: Citation

Title: Zinc and neurogenesis: making new neurons from development to adulthood..
Creator: Levenson, Cathy W, Morris, Deborah
Abstract/Description: Stem cell proliferation, neuronal differentiation, cell survival, and migration in the central nervous system are all important steps in the normal process of neurogenesis. These mechanisms are highly active during gestational and early neonatal brain development. Additionally, in select regions of the brain, stem cells give rise to new neurons throughout the human lifespan. Recent work has revealed key roles for the essential trace element zinc in the control of both developmental and adult...
Show moreStem cell proliferation, neuronal differentiation, cell survival, and migration in the central nervous system are all important steps in the normal process of neurogenesis. These mechanisms are highly active during gestational and early neonatal brain development. Additionally, in select regions of the brain, stem cells give rise to new neurons throughout the human lifespan. Recent work has revealed key roles for the essential trace element zinc in the control of both developmental and adult neurogenesis. Given the prevalence of zinc deficiency, these findings have implications for brain development, cognition, and the regulation of mood.
Show less
Date Issued: 2011-03-01
Identifier: FSU_pmch_22332038, 10.3945/an.110.000174, PMC3065768, 22332038, 22332038, 000174
Format: Citation

Title: The effects of a multi-ingredient supplement on markers of muscle damage and inflammation following downhill running in females.
Creator: Köhne, Jessica L, Ormsbee, Michael J, McKune, Andrew J
Abstract/Description: The effects of a multi-ingredient performance supplement (MIPS) on markers of inflammation and muscle damage, perceived soreness and lower limb performance are unknown in endurance-trained female athletes. The purpose of this study was to determine the impact of MIPS (NO-Shotgun®) pre-loaded 4 weeks prior to a single-bout of downhill running (DHR) on hsC-Reactive Protein (hsCRP), interleukin (IL)-6, creatine kinase (CK), muscle soreness, lower limb circumferences and performance. Trained...
Show moreThe effects of a multi-ingredient performance supplement (MIPS) on markers of inflammation and muscle damage, perceived soreness and lower limb performance are unknown in endurance-trained female athletes. The purpose of this study was to determine the impact of MIPS (NO-Shotgun®) pre-loaded 4 weeks prior to a single-bout of downhill running (DHR) on hsC-Reactive Protein (hsCRP), interleukin (IL)-6, creatine kinase (CK), muscle soreness, lower limb circumferences and performance. Trained female runners ( = 8; 29 ± 5.9 years) (VO: ≥ 50 ml.kg.min, midfollicular phase (7-11 days post-menses) were randomly assigned in a double-blind manner into two groups: MIPS ( = 4) ingested one serving of NO Shotgun daily for 28 days prior to DHR and 30 min prior to all post-testing visits; Control (CON) ( = 4) consumed an isocaloric maltodextrin placebo in an identical manner to MIPS. hsCRP, IL-6, CK, perceived soreness, limb circumferences, and performance measures (flexibility, squat jump peak power) were tested on 5 occasions; immediately before (PRE), immediately post-DHR, 24, 48 and 72 h post-DHR. There were main effects of time for CK ( = 0.05), pain pressure threshold (right tibialis anterior ( = 0.010), right biceps femoris ( = 0.01), and left iliotibial band (ITB) ( = 0.05) across all time points), and maximum squat jump power ( = 0.04). Compared with 24 h post-DHR, maximum squat jump power was significantly lower at 48 h post-DHR ( = 0.05). Lower body perceived soreness was significantly increased at 24 h ( = 0.02) and baseline to 48 h ( = 0.02) post DHR. IL-6 peaked immediately post-DHR ( = 0.03) and hsCRP peaked at 24 h post-DHR ( = 0.06). Calculation of effect sizes indicated a moderate attenuation of hsCRP in MIPS at 72 h post-DHR. Consumption of MIPS for 4 weeks prior to a single bout of DHR attenuated inflammation three days post, but did not affect perceived soreness and muscle damage markers in endurance trained female runners following a single bout of DHR.
Show less
Date Issued: 2016-11-25
Identifier: FSU_pmch_27924138, 10.1186/s12970-016-0156-5, PMC5123227, 27924138, 27924138, 156
Format: Citation

Title: Acoustic Measures of Voice and Physiologic Measures of Autonomic Arousal during Speech as a Function of Cognitive Load.
Creator: MacPherson, Megan K, Abur, Defne, Stepp, Cara E
Abstract/Description: This study aimed to determine the relationship among cognitive load condition and measures of autonomic arousal and voice production in healthy adults. A prospective study design was conducted. Sixteen healthy young adults (eight men, eight women) produced a sentence containing an embedded Stroop task in each of two cognitive load conditions: congruent and incongruent. In both conditions, participants said the font color of the color words instead of the word text. In the incongruent...
Show moreThis study aimed to determine the relationship among cognitive load condition and measures of autonomic arousal and voice production in healthy adults. A prospective study design was conducted. Sixteen healthy young adults (eight men, eight women) produced a sentence containing an embedded Stroop task in each of two cognitive load conditions: congruent and incongruent. In both conditions, participants said the font color of the color words instead of the word text. In the incongruent condition, font color differed from the word text, creating an increase in cognitive load relative to the congruent condition in which font color and word text matched. Three physiologic measures of autonomic arousal (pulse volume amplitude, pulse period, and skin conductance response amplitude) and four acoustic measures of voice (sound pressure level, fundamental frequency, cepstral peak prominence, and low-to-high spectral energy ratio) were analyzed for eight sentence productions in each cognitive load condition per participant. A logistic regression model was constructed to predict the cognitive load condition (congruent or incongruent) using subject as a categorical predictor and the three autonomic measures and four acoustic measures as continuous predictors. It revealed that skin conductance response amplitude, cepstral peak prominence, and low-to-high spectral energy ratio were significantly associated with cognitive load condition. During speech produced under increased cognitive load, healthy young adults show changes in physiologic markers of heightened autonomic arousal and acoustic measures of voice quality. Future work is necessary to examine these measures in older adults and individuals with voice disorders.
Show less
Date Issued: 2017-07-01
Identifier: FSU_pmch_27939119, 10.1016/j.jvoice.2016.10.021, PMC6081741, 27939119, 27939119, S0892-1997(16)30302-2
Format: Citation

Title: Preliminary examination of glucagon-like peptide-1 levels in women with purging disorder and bulimia nervosa.
Creator: Dossat, Amanda M, Bodell, Lindsay P, Williams, Diana L, Eckel, Lisa A, Keel, Pamela K
Abstract/Description: This study examined pre- and postprandial glucagon-like peptide 1 (GLP-1) levels in women with bulimia nervosa (BN), purging disorder (PD), and non-eating disorder control women to better understand whether alterations in satiation-related hormones in BN may be linked to binge-eating episodes or other altered ingestive behaviors. Participants included women with BN (n = 19), PD (n = 14), or controls (n = 14). Participants provided subjective ratings for hunger and fullness and plasma samples...
Show moreThis study examined pre- and postprandial glucagon-like peptide 1 (GLP-1) levels in women with bulimia nervosa (BN), purging disorder (PD), and non-eating disorder control women to better understand whether alterations in satiation-related hormones in BN may be linked to binge-eating episodes or other altered ingestive behaviors. Participants included women with BN (n = 19), PD (n = 14), or controls (n = 14). Participants provided subjective ratings for hunger and fullness and plasma samples before and after consumption of a standardized test meal. As expected, GLP-1 levels increased significantly following test meal consumption; however, participants with BN displayed significantly lower GLP-1 levels compared to PD and control participants both before and after consumption of the test meal. There were no significant differences between PD and control participants in GLP-1 levels, but individuals with PD displayed significantly higher levels of fullness throughout the test meal as compared to both control and BN participants. Our findings provide preliminary evidence that reduced GLP-1 levels in individuals with BN may be associated with binge-eating episodes. Additionally, increased fullness in individuals with PD does not appear to be accounted for by exaggerated postprandial GLP-1 release.
Show less
Date Issued: 2015-03-01
Identifier: FSU_pmch_24590464, 10.1002/eat.22264, PMC4155021, 24590464, 24590464
Format: Citation

Title: Effects of proactive interference on non-verbal working memory.
Creator: Cyr, Marilyn, Nee, Derek E, Nelson, Eric, Senger, Thea, Jonides, John, Malapani, Chara
Abstract/Description: Working memory (WM) is a cognitive system responsible for actively maintaining and processing relevant information and is central to successful cognition. A process critical to WM is the resolution of proactive interference (PI), which involves suppressing memory intrusions from prior memories that are no longer relevant. Most studies that have examined resistance to PI in a process-pure fashion used verbal material. By contrast, studies using non-verbal material are scarce, and it remains...
Show moreWorking memory (WM) is a cognitive system responsible for actively maintaining and processing relevant information and is central to successful cognition. A process critical to WM is the resolution of proactive interference (PI), which involves suppressing memory intrusions from prior memories that are no longer relevant. Most studies that have examined resistance to PI in a process-pure fashion used verbal material. By contrast, studies using non-verbal material are scarce, and it remains unclear whether the effect of PI is domain-general or whether it applies solely to the verbal domain. The aim of the present study was to examine the effect of PI in visual WM using both objects with high and low nameability. Using a Directed-Forgetting paradigm, we varied discriminability between WM items on two dimensions, one verbal (high-nameability vs. low-nameability objects) and one perceptual (colored vs. gray objects). As in previous studies using verbal material, effects of PI were found with object stimuli, even after controlling for verbal labels being used (i.e., low-nameability condition). We also found that the addition of distinctive features (color, verbal label) increased performance in rejecting intrusion probes, most likely through an increase in discriminability between content-context bindings in WM.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_27838866, 10.1007/s10339-016-0784-3, PMC5292286, 27838866, 27838866, 10.1007/s10339-016-0784-3
Format: Citation

Title: Methodological issues in the use of individual brain measures to index trait liabilities: The example of noise-probe P3..
Creator: Perkins, Emily R, Yancey, James R, Drislane, Laura E, Venables, Noah C, Balsis, Steve, Patrick, Christopher J
Abstract/Description: Recent research initiatives have called for an increased use of biological concepts and measures in defining and studying mental health problems, but important measurement-related challenges confront efforts in this direction. This article highlights some of these challenges with reference to an intriguing measure of neural reactivity: the probe P3 response, a mid-latency brain potential evoked by an intense, unexpected acoustic-probe stimulus. Using data for a large adult sample (N=418), we...
Show moreRecent research initiatives have called for an increased use of biological concepts and measures in defining and studying mental health problems, but important measurement-related challenges confront efforts in this direction. This article highlights some of these challenges with reference to an intriguing measure of neural reactivity: the probe P3 response, a mid-latency brain potential evoked by an intense, unexpected acoustic-probe stimulus. Using data for a large adult sample (N=418), we report evidence that amplitude of probe P3 response to unwarned noise bursts occurring in a picture-viewing task exhibits robust, independent associations with two distinct trait constructs: weak inhibitory control (or disinhibition; DIS) and threat sensitivity (THT). Additionally, we report a selective association for THT with attentional suppression of probe P3 response during viewing of aversive pictures compared to neutral. These results point to separable elements of variance underlying the probe P3 response, including one element reflecting DIS-related variations in cognitive-elaborative processing, and others reflecting THT-related variations in aversive foreground engagement and abrupt defensive reorientation. Key measurement issues are considered in relation to these specific findings, and methodological and statistical approaches for addressing these issues are discussed in relation to advancement of a quantitatively sound, biologically informed science of psychopathology.
Show less
Date Issued: 2017-01-01
Identifier: FSU_pmch_27856400, 10.1016/j.ijpsycho.2016.11.012, PMC5222687, 27856400, 27856400, S0167-8760(16)30798-X
Format: Citation

Title: Thwarted belongingness as an explanatory link between insomnia symptoms and suicidal ideation: Findings from three samples of military service members and veterans..
Creator: Hom, Melanie A, Chu, Carol, Schneider, Matthew E, Lim, Ingrid C, Hirsch, Jameson K, Gutierrez, Peter M, Joiner, Thomas E
Abstract/Description: Although insomnia has been identified as a robust predictor of suicidal ideation and behaviors, little is known about the mechanisms by which sleep disturbances confer risk for suicide. We investigated thwarted belongingness as an explanatory link between insomnia symptoms and suicidal ideation across three military service member and veteran samples. Data were collected among United States military service members and veterans (N=937, N=3,386, N=417) who completed self-report measures of...
Show moreAlthough insomnia has been identified as a robust predictor of suicidal ideation and behaviors, little is known about the mechanisms by which sleep disturbances confer risk for suicide. We investigated thwarted belongingness as an explanatory link between insomnia symptoms and suicidal ideation across three military service member and veteran samples. Data were collected among United States military service members and veterans (N=937, N=3,386, N=417) who completed self-report measures of insomnia symptoms, thwarted belongingness, suicidal ideation, and related psychiatric symptoms (e.g., anxiety, hopelessness). Bias-corrected bootstrap mediation analyses were utilized to examine the indirect effects of insomnia symptoms on suicidal ideation through thwarted belongingness, controlling for related psychiatric symptoms. Consistent with study hypotheses, thwarted belongingness significantly accounted for the relationship between insomnia and suicidal ideation across all three samples; however, insomnia symptoms did not significantly account for the relationship between thwarted belongingness and suicidal ideation, highlighting the specificity of our findings. This study utilized cross-sectional self-report data. Insomnia may confer suicide risk for military service members and veterans, in part, through the pathway of thwarted belongingness. Additional prospective studies are warranted to further delineate this model of risk. Our results offer a potential therapeutic target for the prevention of suicide, via the promotion of belongingness, among service members and veterans experiencing insomnia symptoms.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_27898373, 10.1016/j.jad.2016.11.032, PMC5333761, 27898373, 27898373, S0165-0327(16)31413-6
Format: Citation

Title: The moderating influence of heart rate variability on stressor-elicited change in pupillary and attentional indices of emotional processing: An eye-Tracking study..
Creator: Macatee, Richard J, Albanese, Brian J, Schmidt, Norman B, Cougle, Jesse R
Abstract/Description: Low resting heart rate variability (HRV) is associated with a broad array of negative psychosocial outcomes. Recent theoretical explications of HRV suggest it is an autonomic marker of emotion regulation capacity, but limited research has examined its relationship with emotional information processing indices. The present study utilized eye-tracking methodology to test HRV's theorized role as a marker of emotion regulation capacity in a non-clinical sample. Attentional biases towards...
Show moreLow resting heart rate variability (HRV) is associated with a broad array of negative psychosocial outcomes. Recent theoretical explications of HRV suggest it is an autonomic marker of emotion regulation capacity, but limited research has examined its relationship with emotional information processing indices. The present study utilized eye-tracking methodology to test HRV's theorized role as a marker of emotion regulation capacity in a non-clinical sample. Attentional biases towards threatening, dysphoric, and positive emotional information as well as affective modulation of pupil size were assessed before and after a stress induction. Low resting HRV marginally predicted larger increases in attentional bias towards positive emotional stimuli from pre to post-stress induction and significantly predicted decreased pupil dilation to positive stimuli after the stress induction only; exploratory analyses suggested that this pattern might reflect an unsuccessful attempt at anxious mood repair. HRV was unrelated to negative emotional information processing. Findings are consistent with existing theories of HRV's psychological significance and suggest a specific association with altered positive emotional processing under acute stress.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_27916689, 10.1016/j.biopsycho.2016.11.013, PMC5347391, 27916689, 27916689, S0301-0511(16)30362-3
Format: Citation

Title: Emotion dysregulation explains associations between anxiety sensitivity and hazardous drinking and drinking motives among adult treatment-seeking smokers.
Creator: Paulus, Daniel J, Valadka, Jaclyn, Businelle, Michael S, Gallagher, Matthew W, Viana, Andres G, Schmidt, Norman B, Zvolensky, Michael J
Abstract/Description: Smoking and drinking frequently co-occur. For example, alcohol use is associated with smoking lapses during quit attempts. However, little is known regarding psychological factors explaining drinking among smokers. Anxiety sensitivity is a risk factor associated with hazardous drinking and drinking to cope and/or conform, although little is known about mechanisms underlying such associations. One potential explanatory factor is emotion dysregulation. The current study examined emotion...
Show moreSmoking and drinking frequently co-occur. For example, alcohol use is associated with smoking lapses during quit attempts. However, little is known regarding psychological factors explaining drinking among smokers. Anxiety sensitivity is a risk factor associated with hazardous drinking and drinking to cope and/or conform, although little is known about mechanisms underlying such associations. One potential explanatory factor is emotion dysregulation. The current study examined emotion dysregulation as an explanatory factor underlying Anxiety Sensitivity and 5 alcohol-related outcomes: hazardous drinking, alcohol consumption, alcohol problems, coping-oriented drinking, and drinking to conform. Participants for this study were 467 treatment-seeking adult, daily smokers (48.2% women; Mage = 36.7 years, SD = 13.6) who reported smoking an average of 16.5 cigarettes per day. Results indicate significant indirect effects of Anxiety Sensitivity on hazardous drinking via emotion dysregulation, alcohol consumption, alcohol problems, drinking to cope, and drinking to conform. Effects were medium in size. Alternative models testing indirect effects of emotion dysregulation through Anxiety Sensitivity on outcomes, and Anxiety Sensitivity through outcomes on emotion dysregulation were nonsignificant and all had small effect sizes. Follow-up tests examined the path of effects from Anxiety Sensitivity through specific emotion-dysregulation subfactors. Thus, among treatment-seeking smokers, emotion dysregulation may explain the associations of Anxiety Sensitivity with alcohol-related outcomes. This pattern of findings highlights the potential importance of interventions targeting emotion dysregulation among hazardous-drinking smokers. (PsycINFO Database Record
Show less
Date Issued: 2017-03-01
Identifier: FSU_pmch_28080096, 10.1037/adb0000252, PMC5344750, 28080096, 28080096, 2017-01385-001
Format: Citation

Title: Integrative Comparison of mRNA Expression Patterns in Breast Cancers from Caucasian and Asian Americans with Implications for Precision Medicine.
Creator: Shi, Yanxia, Steppi, Albert, Cao, Ye, Wang, Jianan, He, Max M, Li, Liren, Zhang, Jinfeng
Abstract/Description: Asian Americans (AS) have significantly lower incidence and mortality rates of breast cancer than Caucasian Americans (CA). Although this racial disparity has been documented, the underlying pathogenetic factors explaining it are obscure. We addressed this issue by an integrative genomics approach to compare mRNA expression between AS and CA cases of breast cancer. RNA-seq data from the Cancer Genome Atlas showed that mRNA expression revealed significant differences at gene and pathway levels...
Show moreAsian Americans (AS) have significantly lower incidence and mortality rates of breast cancer than Caucasian Americans (CA). Although this racial disparity has been documented, the underlying pathogenetic factors explaining it are obscure. We addressed this issue by an integrative genomics approach to compare mRNA expression between AS and CA cases of breast cancer. RNA-seq data from the Cancer Genome Atlas showed that mRNA expression revealed significant differences at gene and pathway levels. Increased susceptibility and severity in CA patients were likely the result of synergistic environmental and genetic risk factors, with arachidonic acid metabolism and PPAR signaling pathways implicated in linking environmental and genetic factors. An analysis that also added eQTL data from the Genotype-Tissue Expression Project and SNP data from the 1,000 Genomes Project identified several SNPs associated with differentially expressed genes. Overall, the associations we identified may enable a more focused study of genotypic differences that may help explain the disparity in breast cancer incidence and mortality rates in CA and AS populations and inform precision medicine. Cancer Res; 77(2); 423-33. ©2016 AACR.
Show less
Date Issued: 2017-01-15
Identifier: FSU_pmch_28069798, 10.1158/0008-5472.CAN-16-1959, PMC5243181, 28069798, 28069798
Format: Citation

Title: Assessing Vowel Centralization in Dysarthria: A Comparison of Methods..
Creator: Fletcher, Annalise R, McAuliffe, Megan J, Lansford, Kaitlin L, Liss, Julie M
Abstract/Description: The strength of the relationship between vowel centralization measures and perceptual ratings of dysarthria severity has varied considerably across reports. This article evaluates methods of acoustic-perceptual analysis to determine whether procedural changes can strengthen the association between these measures. Sixty-one speakers (17 healthy individuals and 44 speakers with dysarthria) read a standard passage. To obtain acoustic data, 2 points of formant extraction (midpoint and...
Show moreThe strength of the relationship between vowel centralization measures and perceptual ratings of dysarthria severity has varied considerably across reports. This article evaluates methods of acoustic-perceptual analysis to determine whether procedural changes can strengthen the association between these measures. Sixty-one speakers (17 healthy individuals and 44 speakers with dysarthria) read a standard passage. To obtain acoustic data, 2 points of formant extraction (midpoint and articulatory point) and 2 frequency measures (Hz and Bark) were trialed. Both vowel space area and an adapted formant centralization ratio were calculated using first and second formants of speakers' corner vowels. Twenty-eight listeners rated speech samples using different prompts: one with a focus on intelligibility, the other on speech precision. Perceptually, listener ratings of speech precision provided the best index of acoustic change. Acoustically, the combined use of an articulatory-based formant extraction point, Bark frequency units, and the formant centralization ratio was most effective in explaining perceptual ratings. This combination of procedures resulted in an increase of 17% to 27% explained variance between measures. The procedures researchers use to assess articulatory impairment can significantly alter the strength of relationship between acoustic and perceptual measures. Procedures that maximize this relationship are recommended.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_28124069, 10.1044/2016_JSLHR-S-15-0355, PMC6194930, 28124069, 28124069, 2599995
Format: Citation

Title: Understanding the Influence of Stigma and Medical Mistrust on Engagement in Routine Healthcare Among Black Women Who Have Sex with Women.
Creator: Brenick, Alaina, Romano, Kelly, Kegler, Christopher, Eaton, Lisa A
Abstract/Description: For Black women who have sex with women (BWSW), obtaining routine healthcare can be obstructed by a number of psychosocial barriers, including experiences of stigma, related to both sexual orientation and race, and medical mistrust, both race-based and global. Previous research demonstrates that sexual orientation and race-based stigma, as well as global and race-based medical mistrust, each have a negative impact on health outcomes and engagement in care (EIC) independently. This study...
Show moreFor Black women who have sex with women (BWSW), obtaining routine healthcare can be obstructed by a number of psychosocial barriers, including experiences of stigma, related to both sexual orientation and race, and medical mistrust, both race-based and global. Previous research demonstrates that sexual orientation and race-based stigma, as well as global and race-based medical mistrust, each have a negative impact on health outcomes and engagement in care (EIC) independently. This study addresses gaps in the literature by examining the impact of these psychosocial barriers and their interactions among BWSW, an understudied population. Participants (256 BWSW) were surveyed at a Black Gay Pride festival. Separate generalized linear models assessed the independent and multiplicative effects of participants' self-reported sexual orientation stigma, race-based stigma, race-based medical mistrust, and global medical mistrust related to their engagement in routine physical exams and blood pressure screenings. Prevalence rates of both stigma measures were low, but prevalence rates of global and race-based medical mistrust were high. The results show that experiencing sexual orientation stigma or having race-based medical mistrust predicts significantly lower EIC. Furthermore, the frequencies of obtaining recent physical examinations and blood pressure screenings were significantly related to three- and two-way interactions between stigma and medical mistrust, respectively. There is an urgent need to address the intersectionality of these psychosocial barriers in an effort to increase BWSW's EIC.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_28113005, 10.1089/lgbt.2016.0083, PMC5278794, 28113005, 28113005
Format: Citation

Title: Surface-based morphometry reveals the neuroanatomical basis of the five-factor model of personality.
Creator: Riccelli, Roberta, Toschi, Nicola, Nigro, Salvatore, Terracciano, Antonio, Passamonti, Luca
Abstract/Description: The five-factor model (FFM) is a widely used taxonomy of human personality; yet its neuro anatomical basis remains unclear. This is partly because past associations between gray-matter volume and FFM were driven by different surface-based morphometry (SBM) indices (i.e. cortical thickness, surface area, cortical folding or any combination of them). To overcome this limitation, we used Free-Surfer to study how variability in SBM measures was related to the FFM in n = 507 participants from the...
Show moreThe five-factor model (FFM) is a widely used taxonomy of human personality; yet its neuro anatomical basis remains unclear. This is partly because past associations between gray-matter volume and FFM were driven by different surface-based morphometry (SBM) indices (i.e. cortical thickness, surface area, cortical folding or any combination of them). To overcome this limitation, we used Free-Surfer to study how variability in SBM measures was related to the FFM in n = 507 participants from the Human Connectome Project.Neuroticism was associated with thicker cortex and smaller area and folding in prefrontal-temporal regions. Extraversion was linked to thicker pre-cuneus and smaller superior temporal cortex area. Openness was linked to thinner cortex and greater area and folding in prefrontal-parietal regions. Agreeableness was correlated to thinner prefrontal cortex and smaller fusiform gyrus area. Conscientiousness was associated with thicker cortex and smaller area and folding in prefrontal regions. These findings demonstrate that anatomical variability in prefrontal cortices is linked to individual differences in the socio-cognitive dispositions described by the FFM. Cortical thickness and surface area/folding were inversely related each others as a function of different FFM traits (neuroticism, extraversion and consciousness vs openness), which may reflect brain maturational effects that predispose or protect against psychiatric disorders.
Show less
Date Issued: 2017-04-01
Identifier: FSU_pmch_28122961, 10.1093/scan/nsw175, PMC5390726, 28122961, 28122961, nsw175
Format: Citation

Title: Caregiver perceptions of childhood weight: demographic moderators and correlates..
Creator: Miller, D, Johnson, W, Miller, M, Miller, J, Sutin, A R
Abstract/Description: To examine whether ethnicity moderates the association between caregiver characteristics and perceptions of childhood weight and whether these perceptions are associated with their child's obesity status. Caregivers recruited from paediatricians' offices (n = 453) completed a survey about childhood health; nurses weighed and measured the children. Caregivers reported their own weight and height, demographic information about their family and made ratings of healthy weight for children in...
Show moreTo examine whether ethnicity moderates the association between caregiver characteristics and perceptions of childhood weight and whether these perceptions are associated with their child's obesity status. Caregivers recruited from paediatricians' offices (n = 453) completed a survey about childhood health; nurses weighed and measured the children. Caregivers reported their own weight and height, demographic information about their family and made ratings of healthy weight for children in general and for their own child in particular. African American caregivers were more likely to view heavier girls as healthier, but this association held only for lower income families or caregivers with higher body mass index. Hispanic caregivers were more likely to misperceive their own child's weight if either the caregiver or the child had a higher body mass index. Parents who perceived heavier weight as healthier or misperceived their own child's weight were more likely to have a child with obesity. This latter association held regardless of ethnicity. The association between ethnicity and perceptions of healthy childhood weight are complex. The relation between caregivers' perceptions of healthy weight and their own child's obesity status, however, was similar regardless of ethnicity.
Show less
Date Issued: 2016-05-01
Identifier: FSU_pmch_26821665, 10.1111/cch.12318, PMC4841719, 26821665, 26821665
Format: Citation

Title: Weight discrimination and unhealthy eating-related behaviors.
Creator: Sutin, Angelina, Robinson, Eric, Daly, Michael, Terracciano, Antonio
Abstract/Description: Individuals with obesity often experience unfair treatment because of their body weight. Such experiences are associated with binge eating, but less is known about its association with other eating-related behaviors and whether these relations are specific to discrimination based on weight or extend to other attributions for discrimination. The present research uses a large national sample (N = 5129) to examine whether weight discrimination is associated with diet and meal rhythmicity, in...
Show moreIndividuals with obesity often experience unfair treatment because of their body weight. Such experiences are associated with binge eating, but less is known about its association with other eating-related behaviors and whether these relations are specific to discrimination based on weight or extend to other attributions for discrimination. The present research uses a large national sample (N = 5129) to examine whether weight discrimination is associated with diet and meal rhythmicity, in addition to overeating, and whether these associations generalize to nine other attributions for discrimination. We found that in addition to overeating, weight discrimination was associated with more frequent consumption of convenience foods and less regular meal timing. These associations were generally similar across sex, age, and race. Discrimination based on ancestry, gender, age, religion, and physical disability were also associated with overeating, which suggests that overeating may be a general coping response to discrimination. Unfair treatment because of body weight is associated with unhealthy eating-related behaviors, which may be one pathway through which weight discrimination increases risk for weight gain and obesity.
Show less
Date Issued: 2016-07-01
Identifier: FSU_pmch_26877216, 10.1016/j.appet.2016.02.016, PMC4866877, 26877216, 26877216, S0195-6663(16)30051-4
Format: Citation

Title: Anxiety sensitivity risk reduction in smokers: A randomized control trial examining effects on panic..
Creator: Schmidt, Norman B, Raines, Amanda M, Allan, Nicholas P, Zvolensky, Michael J
Abstract/Description: Empirical evidence has identified several risk factors for panic psychopathology, including smoking and anxiety sensitivity (AS; the fear of anxiety-related sensations). Smokers with elevated AS are therefore a particularly vulnerable population for panic. Yet, there is little knowledge about how to reduce risk of panic among high AS smokers. The present study prospectively evaluated panic outcomes within the context of a controlled randomized risk reduction program for smokers. Participants ...
Show moreEmpirical evidence has identified several risk factors for panic psychopathology, including smoking and anxiety sensitivity (AS; the fear of anxiety-related sensations). Smokers with elevated AS are therefore a particularly vulnerable population for panic. Yet, there is little knowledge about how to reduce risk of panic among high AS smokers. The present study prospectively evaluated panic outcomes within the context of a controlled randomized risk reduction program for smokers. Participants (N = 526) included current smokers who all received a state-of-the-art smoking cessation intervention with approximately half randomized to the AS reduction intervention termed Panic-smoking Program (PSP). The primary hypotheses focus on examining the effects of a PSP on panic symptoms in the context of this vulnerable population. Consistent with prediction, there was a significant effect of treatment condition on AS, such that individuals in the PSP condition, compared to those in the control condition, demonstrated greater decreases in AS throughout treatment and the follow-up period. In addition, PSP treatment resulted in lower rates of panic-related symptomatology. Moreover, mediation analyses indicated that reductions in AS resulted in lower panic symptoms. The present study provides the first empirical evidence that brief, targeted psychoeducational interventions can mitigate panic risk among smokers.
Show less
Date Issued: 2016-02-01
Identifier: FSU_pmch_26752327, 10.1016/j.brat.2015.12.011, PMC4752863, 26752327, 26752327, S0005-7967(15)30075-9
Format: Citation

Title: Does Suicidal Ideation Influence Memory? A Study of the Role of Violent Daydreaming in the Relationship Between Suicidal Ideation and Everyday Memory.
Creator: Chu, Carol, Podlogar, Matthew C, Rogers, Megan L, Buchman-Schmitt, Jennifer M, Negley, Jacob H, Joiner, Thomas E
Abstract/Description: Individuals at risk for suicide experience periods of emotional, enduring, and vivid thoughts about their death by suicide and frequently report violent daydreams about death. Daydreaming is associated with forgetfulness and memory impairments. However, no studies have examined whether suicidal ideation is associated with deficits in everyday memory capabilities and whether violent daydreaming may influence these relationships. This study tested these hypotheses in a sample of 512 young...
Show moreIndividuals at risk for suicide experience periods of emotional, enduring, and vivid thoughts about their death by suicide and frequently report violent daydreams about death. Daydreaming is associated with forgetfulness and memory impairments. However, no studies have examined whether suicidal ideation is associated with deficits in everyday memory capabilities and whether violent daydreaming may influence these relationships. This study tested these hypotheses in a sample of 512 young adults. Self-report measures of subjective everyday memory capabilities, violent daydreaming, and suicidal ideation were administered. Results indicated that suicidal ideation and violent daydreaming were each significantly associated with greater impairments in everyday memory retrieval and everyday memory encoding (i.e., attentional tracking). Furthermore, violent daydreaming accounted for the relationship between suicidal ideation and impairments in everyday memory retrieval and memory encoding. Notably, findings remained after controlling for gender and depressive symptoms, a robust predictor of memory impairments. Implications and limitations are discussed.
Show less
Date Issued: 2016-09-01
Identifier: FSU_pmch_26798081, 10.1177/0145445515625189, PMC4956597, 26798081, 26798081, 0145445515625189
Format: Citation

Title: Binge Drinking in Young Adulthood: The Influence of Age at First Intercourse and Rate of Sex Partner Accumulation..
Creator: Holway, Giuseppina Valle, Tillman, Kathryn Harker, Brewster, Karin L
Abstract/Description: There has been growing attention to the influence of youths' sexual experiences on alcohol use and other health-risk behaviors. Yet, because of the cross-sectional nature of many studies, as well as the likelihood of alcohol use and sexual behaviors to co-occur, the question of whether initiation of sexual activity tends to precede engagement in other behaviors, like binge drinking, remains largely unanswered. Using data from 4726 respondents who participated in Waves I through IV of the...
Show moreThere has been growing attention to the influence of youths' sexual experiences on alcohol use and other health-risk behaviors. Yet, because of the cross-sectional nature of many studies, as well as the likelihood of alcohol use and sexual behaviors to co-occur, the question of whether initiation of sexual activity tends to precede engagement in other behaviors, like binge drinking, remains largely unanswered. Using data from 4726 respondents who participated in Waves I through IV of the National Longitudinal Study of Adolescent to Adult Health (Add Health), we examined the association between age at first intercourse and frequent binge drinking during one's mid-twenties and early thirties. We further explored whether this relationship was mediated or moderated by the rate at which individuals accumulated sex partners during the transition to adulthood. Findings showed for women and men, later ages at first intercourse were associated with lower odds of frequent binge drinking in young adulthood. While rate of sex partner accumulation partially mediated this association, it did not moderate it. Furthermore, rate of partner accumulation was positively associated with binge drinking, particularly among women, with a quicker accumulation of sex partners associated with a higher likelihood of engaging in frequent binge drinking. Our findings underscore the importance of considering multiple dimensions of a single behavior and their relation to subsequent health-related behaviors.
Show less
Date Issued: 2017-02-01
Identifier: FSU_pmch_26400653, 10.1007/s10508-015-0597-y, PMC4828321, 26400653, 26400653, 10.1007/s10508-015-0597-y
Format: Citation

Title: Personality traits and body mass index: Modifiers and mechanisms..
Creator: Sutin, Angelina R, Terracciano, Antonio
Abstract/Description: To identify how demographic factors (sex, age, ethnicity) modify the association between personality traits and body mass index (BMI) and to test the extent that diet and physical activity account for the personality-BMI relations. Cross-sectional study with a diverse sample (N = 5150, 50% female, 19% African American, 15% Hispanic). Participants completed a measure of the five major dimensions of personality and reported on their physical activity, diet and food intake behaviour, and height...
Show moreTo identify how demographic factors (sex, age, ethnicity) modify the association between personality traits and body mass index (BMI) and to test the extent that diet and physical activity account for the personality-BMI relations. Cross-sectional study with a diverse sample (N = 5150, 50% female, 19% African American, 15% Hispanic). Participants completed a measure of the five major dimensions of personality and reported on their physical activity, diet and food intake behaviour, and height and weight. BMI and obesity (BMI ≥ 30). High Neuroticism was associated with higher BMI and risk for obesity, whereas Conscientiousness and, to a lesser extent, Extraversion and Openness were protective. These associations were generally stronger among women and older participants; there was less evidence for ethnicity as a moderator. Personality had similar relations with the behavioural factors, and physical activity, diet and regular meal rhythms accounted for approximately 50% of the association between Neuroticism and Conscientiousness and BMI. This study supports the links between personality traits and BMI and suggests that physical activity, more than diet, is a key factor in these associations.
Show less
Date Issued: 2016-01-01
Identifier: FSU_pmch_26274568, 10.1080/08870446.2015.1082561, PMC4827155, 26274568, 26274568
Format: Citation

Title: Summer indoor heat exposure and respiratory and cardiovascular distress calls in New York City, NY, U.S.
Creator: Uejio, C K, Tamerius, J D, Vredenburg, J, Asaeda, G, Isaacs, D A, Braun, J, Quinn, A, Freese, J P
Abstract/Description: Most extreme heat studies relate outdoor weather conditions to human morbidity and mortality. In developed nations, individuals spend ~90% of their time indoors. This pilot study investigated the indoor environments of people receiving emergency medical care in New York City, NY, U.S., from July to August 2013. The first objective was to determine the relative influence of outdoor conditions as well as patient characteristics and neighborhood sociodemographics on indoor temperature and...
Show moreMost extreme heat studies relate outdoor weather conditions to human morbidity and mortality. In developed nations, individuals spend ~90% of their time indoors. This pilot study investigated the indoor environments of people receiving emergency medical care in New York City, NY, U.S., from July to August 2013. The first objective was to determine the relative influence of outdoor conditions as well as patient characteristics and neighborhood sociodemographics on indoor temperature and specific humidity (N = 764). The second objective was to determine whether cardiovascular or respiratory cases experience hotter and more humid indoor conditions as compared to controls. Paramedics carried portable sensors into buildings where patients received care to passively monitor indoor temperature and humidity. The case-control study compared 338 respiratory cases, 291 cardiovascular cases, and 471 controls. Intuitively, warmer and sunnier outdoor conditions increased indoor temperatures. Older patients who received emergency care tended to occupy warmer buildings. Indoor-specific humidity levels quickly adjusted to outdoor conditions. Indoor heat and humidity exposure above a 26 °C threshold increased (OR: 1.63, 95% CI: 0.98-2.68, P = 0.056), but not significantly, the proportion of respiratory cases. Indoor heat exposures were similar between cardiovascular cases and controls.
Show less
Date Issued: 2016-08-01
Identifier: FSU_pmch_26086869, 10.1111/ina.12227, PMC4786471, 26086869, 26086869
Format: Citation

Title: The effect of tailored Web-based interventions on pain in adults: a systematic review protocol..
Creator: Martorella, Géraldine, Gélinas, C, Bérubé, M, Boitor, M, Fredericks, S, LeMay, S
Abstract/Description: Information technologies can facilitate the implementation of health interventions, especially in the case of widespread conditions such as pain. Tailored Web-based interventions have been recognized for health behavior change among diverse populations. However, none of the systematic reviews looking at Web-based interventions for pain management has specifically addressed the contribution of tailoring. The aims of this systematic review are to assess the effect of tailored Web-based pain...
Show moreInformation technologies can facilitate the implementation of health interventions, especially in the case of widespread conditions such as pain. Tailored Web-based interventions have been recognized for health behavior change among diverse populations. However, none of the systematic reviews looking at Web-based interventions for pain management has specifically addressed the contribution of tailoring. The aims of this systematic review are to assess the effect of tailored Web-based pain management interventions on pain intensity and physical and psychological functions. Randomized controlled trials including adults suffering from any type of pain and involving Web-based interventions for pain management, using at least one of the three tailoring strategies (personalization, feedback, or adaptation), will be considered. The following types of comparisons will be carried out: tailored Web-based intervention with (1) usual care (passive control group), (2) face-to-face intervention, and (3) standardized Web-based intervention. The primary outcome will be pain intensity measured using a self-report measure such as the numeric rating scale (e.g., 0-10) or visual analog scale (e.g., 0-100). Secondary outcomes will include pain interference with activities and psychological well-being. A systematic review of English and French articles using MEDLINE, Embase, CINAHL, PsycINFO, Web of Science, and Cochrane Library will be conducted from January 2000 to December 2015. Eligibility assessment will be performed independently in an unblinded standardized manner by two reviewers. Extracted data will include the following: sample size, demographics, dropout rate, number and type of study groups, type of pain, inclusion and exclusion criteria, study setting, type of Web-based intervention, tailoring strategy, comparator, type of pain intensity measure, pain-related disability and psychological well-being outcomes, and times of measurement. Disagreements between reviewers at the full-text level will be resolved by consulting a third reviewer, a senior researcher. This systematic review is the first one looking at the specific ingredients and effects of tailored and Web-based interventions for pain management. Results of this systematic review could contribute to a better understanding of the mechanisms by which Web-based interventions could be helpful for people facing pain problems. PROSPERO CRD42015027669.
Show less
Date Issued: 2016-04-12
Identifier: FSU_pmch_27072140, 10.1186/s13643-016-0233-5, PMC4830009, 27072140, 27072140, 10.1186/s13643-016-0233-5
Format: Citation

Title: A test of the interpersonal theory of suicide in a large sample of current firefighters.
Creator: Chu, Carol, Buchman-Schmitt, Jennifer M, Hom, Melanie A, Stanley, Ian H, Joiner, Thomas E
Abstract/Description: Recent research suggests that firefighters experience elevated rates of suicidal ideation and behaviors. The interpersonal theory of suicide may shed light on this finding. This theory postulates that suicidal desire is strongest among individuals experiencing perceived burdensomeness and thwarted belongingness, and that the combination of suicide desire and acquired capability for suicide is necessary for the development of suicidal behaviors. We tested the propositions of the interpersonal...
Show moreRecent research suggests that firefighters experience elevated rates of suicidal ideation and behaviors. The interpersonal theory of suicide may shed light on this finding. This theory postulates that suicidal desire is strongest among individuals experiencing perceived burdensomeness and thwarted belongingness, and that the combination of suicide desire and acquired capability for suicide is necessary for the development of suicidal behaviors. We tested the propositions of the interpersonal theory in a large sample of current United States firefighters (N=863). Participants completed self-report measures of perceived burdensomeness, thwarted belongingness, fearlessness about death (FAD; a component of acquired capability), and career suicidal ideation and suicide attempt history. Regression models were used to examine the association between interpersonal theory constructs, career suicidal ideation severity, and the presence of career suicide attempts. In line with theory predictions, the three-way interaction between perceived burdensomeness, thwarted belongingness, and FAD was significantly associated with career suicide attempts, beyond participant sex. However, findings were no longer significant after accounting for years of firefighter service or age. Contrary to predictions, the two-way interaction between perceived burdensomeness and thwarted belongingness was not significantly related to career suicidal ideation severity. Applications of the theory to firefighters and future research are discussed.
Show less
Date Issued: 2016-06-30
Identifier: FSU_pmch_27078756, 10.1016/j.psychres.2016.03.041, PMC5333767, 27078756, 27078756, S0165-1781(15)30197-9
Format: Citation

Title: Posttraumatic stress symptom severity and cognitive-based smoking processes among trauma-exposed treatment-seeking smokers: The role of perceived stress..
Creator: Garey, Lorra, Bakhshaie, Jafar, Vujanovic, Anka A, Reitzel, Lorraine R, Schmidt, Norman B, Zvolensky, Michael J
Abstract/Description: Trauma exposure and smoking co-occur at an alarmingly high rate. However, there is little understanding of the mechanisms underlying this clinically significant relation. The present study examined perceived stress as an explanatory mechanism linking posttraumatic stress symptom severity and smoking-specific avoidance/inflexibility, perceived barriers to smoking cessation, and negative affect reduction/negative reinforcement expectancies from smoking among trauma-exposed smokers. Participants...
Show moreTrauma exposure and smoking co-occur at an alarmingly high rate. However, there is little understanding of the mechanisms underlying this clinically significant relation. The present study examined perceived stress as an explanatory mechanism linking posttraumatic stress symptom severity and smoking-specific avoidance/inflexibility, perceived barriers to smoking cessation, and negative affect reduction/negative reinforcement expectancies from smoking among trauma-exposed smokers. Participants were trauma-exposed, treatment-seeking daily cigarette smokers (n=179; 48.0% female; Mage=41.17; SD=12.55). Results indicated that posttraumatic stress symptom severity had an indirect significant effect on each of the dependent variables via perceived stress. The present results provide empirical support that perceived stress may be an underlying mechanism that indirectly explains posttraumatic symptoms relation to smoking-specific avoidance/inflexibility, perceived barriers to smoking cessation, and negative affect reduction/negative reinforcement expectancies among trauma-exposed smokers. These findings suggest that there may be clinical utility in targeting perceived stress among trauma-exposed smokers via stress management psychoeducation and skills training.
Show less
Date Issued: 2016-09-01
Identifier: FSU_pmch_27100473, 10.1016/j.addbeh.2016.03.038, PMC4884455, 27100473, 27100473, S0306-4603(16)30140-X
Format: Citation

Title: Parental Estimation of Their Child's Increased Type 1 Diabetes Risk During the First 2 Years of Participation in an International Observational Study: Results From the TEDDY study..
Creator: Swartling, Ulrica, Lynch, Kristian, Smith, Laura, Johnson, Suzanne Bennett
Abstract/Description: This study assessed mothers' and fathers' perception of their child's risk of getting type 1 diabetes (T1D) during the first 2 years of their participation in The Environmental Determinants of Diabetes in the Young (TEDDY) study. TEDDY parents were informed of their child's increased genetic risk for T1D at study inception. Parent perception of the child's risk was assessed at 3, 6, 15, and 27 months of age. In families with no history of T1D, underestimation of the child's T1D risk was...
Show moreThis study assessed mothers' and fathers' perception of their child's risk of getting type 1 diabetes (T1D) during the first 2 years of their participation in The Environmental Determinants of Diabetes in the Young (TEDDY) study. TEDDY parents were informed of their child's increased genetic risk for T1D at study inception. Parent perception of the child's risk was assessed at 3, 6, 15, and 27 months of age. In families with no history of T1D, underestimation of the child's T1D risk was common in mothers (>38%) and more so in fathers (>50%). The analyses indicated that parental education, country of residence, family history of T1D, household crowding, ethnic minority status, and beliefs that the child's T1D risk can be reduced were factors associated with parental risk perception accuracy. Even when given extensive information about their child's T1D risk, parents often fail to accurately grasp the information provided. This is particularly true for fathers, families from low socioeconomic backgrounds, and those with no family history of T1D. It is important to develop improved tools for risk communication tailored to individual family needs.
Show less
Date Issued: 2016-04-01
Identifier: FSU_pmch_27241873, 10.1177/1556264616648589, PMC4917467, 27241873, 27241873, 1556264616648589
Format: Citation

Title: Gender specific profiles of white coat and masked hypertension impacts on arterial structure and function in the SardiNIA study.
Creator: Scuteri, Angelo, Morrell, Christopher H, Orru', Marco, AlGhatrif, Majid, Saba, Pier Sergio, Terracciano, Antonio, Ferreli, Liana Anna Pina, Loi, Francesco, Marongiu, Michele,...
Show moreScuteri, Angelo, Morrell, Christopher H, Orru', Marco, AlGhatrif, Majid, Saba, Pier Sergio, Terracciano, Antonio, Ferreli, Liana Anna Pina, Loi, Francesco, Marongiu, Michele, Pilia, Maria Grazia, Delitala, Alessandro, Tarasov, Kirill V, Schlessinger, David, Ganau, Antonello, Cucca, Francesco, Lakatta, Edward G
Show less
Date Issued: 2016-08-15
Identifier: FSU_pmch_27179214, 10.1016/j.ijcard.2016.04.172, PMC5206901, 27179214, 27179214, S0167-5273(16)30875-0
Format: Citation

Title: John Henryism Active Coping as a Cultural Correlate of Substance Abuse Treatment Participation Among African American Women.
Creator: Stevens-Watkins, Danelle, Knighton, Joi-Sheree', Allen, Kristin, Fisher, Sycarah, Crowell, Candice, Mahaffey, Carlos, Leukefeld, Carl, Oser, Carrie
Abstract/Description: The rates of illicit drug use among African American women are increasing, yet African American women are least likely to participate in treatment for substance use disorders when compared to women of other racial groups. The current study examined family history of substance use, perceived family support, and John Henryism Active Coping (JHAC) as correlates to seeking treatment for substance abuse. The underlying theoretical frame of JHAC (James et al., 1983) suggests that despite limited...
Show moreThe rates of illicit drug use among African American women are increasing, yet African American women are least likely to participate in treatment for substance use disorders when compared to women of other racial groups. The current study examined family history of substance use, perceived family support, and John Henryism Active Coping (JHAC) as correlates to seeking treatment for substance abuse. The underlying theoretical frame of JHAC (James et al., 1983) suggests that despite limited resources and psychosocial stressors, African Americans believe that hard work and self-determination are necessary to cope with adversities. The current study is a secondary data analyses of 206 drug-using African American women (N=104 urban community women with no criminal justice involvement and N=102 women living in the community on supervised probation) from urban cities in a southern state. It was expected that African American women with a family history of substance abuse, higher levels of perceived family support, and more active coping skills would be more likely to have participated in substance abuse treatment. Step-wise logistic regression results reveal that women on probation, had children, and had a family history of substance abuse were significantly more likely to report participating in substance abuse treatment. Perceived family support and active coping were significant negative correlates of participating in treatment. Implication of results suggests coping with psychosocial stressors using a self-determined and persistent coping strategy may be problematic for drug-using women with limited resources.
Show less
Date Issued: 2016-04-01
Identifier: FSU_pmch_26899801, 10.1016/j.jsat.2016.01.004, PMC4793159, 26899801, 26899801, S0740-5472(16)00017-9
Format: Citation

Title: Examining an underlying mechanism between perceived stress and smoking cessation-related outcomes.
Creator: Robles, Zuzuky, Garey, Lorra, Hogan, Julianna, Bakhshaie, Jafar, Schmidt, Norman B, Zvolensky, Michael J
Abstract/Description: The mediational role of negative reinforcement smoking outcome expectancies in the relation between perceived stress and (1) perceived barriers to cessation, (2) severity of problematic symptoms during past quit attempts, and (3) smoking-specific experiential avoidance (AIS) was examined. Data were drawn from a baseline assessment of a larger clinical trial. Participants included 332 adult treatment-seeking smokers (47.3% female; Mage=38.45; SD=.50; age range: 18-65 years). Results indicated...
Show moreThe mediational role of negative reinforcement smoking outcome expectancies in the relation between perceived stress and (1) perceived barriers to cessation, (2) severity of problematic symptoms during past quit attempts, and (3) smoking-specific experiential avoidance (AIS) was examined. Data were drawn from a baseline assessment of a larger clinical trial. Participants included 332 adult treatment-seeking smokers (47.3% female; Mage=38.45; SD=.50; age range: 18-65 years). Results indicated that perceived stress was indirectly related to perceived barriers to smoking cessation, severity of problematic symptoms during past quit attempts, and AIS through negative reinforcement outcome expectancies. These results were evident after accounting for the variance explained by gender, negative affectivity, and alternative outcome expectancies for smoking. The present findings suggest that smokers with greater perceived stress experience greater negative reinforcement smoking expectancies, which in turn, may be related to numerous processes involved in the maintenance of smoking.
Show less
Date Issued: 2016-07-01
Identifier: FSU_pmch_26946445, 10.1016/j.addbeh.2016.02.022, PMC5531612, 26946445, 26946445, S0306-4603(16)30056-9
Format: Citation

Title: "Do unto others"? Distinct psychopathy facets predict reduced perception and tolerance of pain.
Creator: Brislin, Sarah J, Buchman-Schmitt, Jennifer M, Joiner, Thomas E, Patrick, Christopher J
Abstract/Description: Recent research has sought to understand how individuals high in psychopathic traits perceive pain in others (Decety, Skelly, & Kiehl, 2013; Marsh et al., 2013). Perception of pain in others is presumed to act as a prosocial signal, and underreactivity to others' pain may contribute to engagement in exploitative-aggressive behaviors among individuals high in psychopathic traits (Jackson, Meltzoff, & Decety, 2005). The current study tested for associations between facets of psychopathy as...
Show moreRecent research has sought to understand how individuals high in psychopathic traits perceive pain in others (Decety, Skelly, & Kiehl, 2013; Marsh et al., 2013). Perception of pain in others is presumed to act as a prosocial signal, and underreactivity to others' pain may contribute to engagement in exploitative-aggressive behaviors among individuals high in psychopathic traits (Jackson, Meltzoff, & Decety, 2005). The current study tested for associations between facets of psychopathy as defined by the triarchic model (Patrick, Fowles, & Krueger, 2009) and decreased sensitivity to pain in 105 undergraduates tested in a laboratory pain assessment. A pressure algometer was used to index pain tolerance, and participants also rated their perceptions of and reactivity to the algometer-induced pain during the assessment and again 3 days later. A unique positive relationship was found between pain tolerance and the meanness facet of psychopathy, which also predicted reduced fear of painful algometer stimulation. Other psychopathy facets (boldness, disinhibition) showed negative relations with fear of pain stimulation during testing and at follow-up. Findings from this study extend the nomological network surrounding callousness (meanness) and suggest that increased pain tolerance may be a mechanism contributing to insensitivity to expressions of discomfort in others. (PsycINFO Database Record
Show less
Date Issued: 2016-07-01
Identifier: FSU_pmch_26950545, 10.1037/per0000180, PMC4929019, 26950545, 26950545, 2016-11415-001
Format: Citation

Title: Personality Disorder Symptoms and Suicidality: Low Desire and High Plans for Suicide in Military Inpatients and Outpatients..
Creator: Chu, Carol, Buchman-Schmitt, Jennifer M, Joiner, Thomas E, Rudd, M David
Abstract/Description: This study characterizes the personality disorder (PD) symptoms of patients who endorse a perplexing combination of low desire and high plans for suicide. Five PD (antisocial, narcissistic, borderline, dependent, avoidant) symptoms were examined at the junction of two suicide risk factors: (a) suicidal desire/ideation and (b) resolved plans/preparations. Participants (N = 250) were recruited from U.S. Army Medical Center affiliated sites, including two outpatient clinics, an inpatient...
Show moreThis study characterizes the personality disorder (PD) symptoms of patients who endorse a perplexing combination of low desire and high plans for suicide. Five PD (antisocial, narcissistic, borderline, dependent, avoidant) symptoms were examined at the junction of two suicide risk factors: (a) suicidal desire/ideation and (b) resolved plans/preparations. Participants (N = 250) were recruited from U.S. Army Medical Center affiliated sites, including two outpatient clinics, an inpatient facility, and an emergency room. Self-report measures of PD and suicide symptoms were administered. The interaction of desire and plans was entered into multiple regression equations predicting PD symptoms. Patients endorsing low desire and high plans for suicide reported significantly more antisocial and narcissistic symptoms and fewer borderline, avoidant, and dependent PD symptoms. These findings support the existence of patients who endorse suicide plans in the absence of strong suicidal desire and suggest that they display antisocial and narcissistic personality characteristics. Future directions and clinical implications are discussed.
Show less
Date Issued: 2017-04-01
Identifier: FSU_pmch_26959962, 10.1521/pedi_2016_30_241, PMC5311028, 26959962, 26959962
Format: Citation

Title: Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
Creator: Hoyne, Gerard, Rudnicka, Caroline, Sang, Qing-Xiang, Roycik, Mark, Howarth, Sarah, Leedman, Peter, Schlaich, Markus, Candy, Patrick, Matthews, Vance
Abstract/Description: Prostate cancer is the second most frequently diagnosed cancer in men worldwide. Current treatments include surgery, androgen ablation and radiation. Introduction of more targeted therapies in prostate cancer, based on a detailed knowledge of the signalling pathways, aims to reduce side effects, leading to better clinical outcomes for the patient. ADAM19 (A Disintegrin And Metalloproteinase 19) is a transmembrane and soluble protein which can regulate cell phenotype through cell adhesion and...
Show moreProstate cancer is the second most frequently diagnosed cancer in men worldwide. Current treatments include surgery, androgen ablation and radiation. Introduction of more targeted therapies in prostate cancer, based on a detailed knowledge of the signalling pathways, aims to reduce side effects, leading to better clinical outcomes for the patient. ADAM19 (A Disintegrin And Metalloproteinase 19) is a transmembrane and soluble protein which can regulate cell phenotype through cell adhesion and proteolysis. ADAM19 has been positively associated with numerous diseases, but has not been shown to be a tumor suppressor in the pathogenesis of any human cancers. Our group sought to investigate the role of ADAM19 in human prostate cancer. ADAM19 mRNA and protein levels were assessed in well characterised human prostate cancer cohorts. ADAM19 expression was assessed in normal prostate epithelial cells (RWPE-1) and prostate cancer cells (LNCaP, PC3) using western blotting and immunocytochemistry. Proliferation assays were conducted in LNCaP cells in which ADAM19 was over-expressed. In vitro scratch assays were performed in PC3 cells over-expressing ADAM19. Immunohistochemical studies highlighted that ADAM19 protein levels were elevated in normal prostate tissue compared to prostate cancer biopsies. Results from the clinical cohorts demonstrated that high levels of ADAM19 in microarrays are positively associated with lower stage (p = 0.02591) and reduced relapse (p = 0.00277) of human prostate cancer. In vitro, ADAM19 expression was higher in RWPE-1 cells compared to LNCaP cells. In addition, human ADAM19 over-expression reduced LNCaP cell proliferation and PC3 cell migration. Taken together, our immunohistochemical and microarray results and cellular studies have shown for the first time that ADAM19 is a protective factor for human prostate cancer. Further, this study suggests that upregulation of ADAM19 expression could be of therapeutic potential in human prostate cancer.
Show less
Date Issued: 2016-02-24
Identifier: FSU_pmch_26912236, 10.1186/s12885-016-2178-4, PMC4766641, 26912236, 26912236, 10.1186/s12885-016-2178-4
Format: Citation

Title: Depressive symptoms in third-grade teachers: relations to classroom quality and student achievement..
Creator: McLean, Leigh, McDonald Connor, Carol
Abstract/Description: This study investigated associations among third-grade teachers' (N = 27) symptoms of depression, quality of the classroom-learning environment (CLE), and students' (N = 523, Mage = 8.6 years) math and literacy performance. teachers' depressive symptoms in the winter negatively predicted students' spring mathematics achievement. This depended on students' fall mathematics scores; students who began the year with weaker math skills and were in classrooms where teachers reported more...
Show moreThis study investigated associations among third-grade teachers' (N = 27) symptoms of depression, quality of the classroom-learning environment (CLE), and students' (N = 523, Mage = 8.6 years) math and literacy performance. teachers' depressive symptoms in the winter negatively predicted students' spring mathematics achievement. This depended on students' fall mathematics scores; students who began the year with weaker math skills and were in classrooms where teachers reported more depressive symptoms achieved smaller gains than did peers whose teachers reported fewer symptoms. teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement. The findings point to the importance of teachers' mental health, with implications for policy and practice.
Show less
Date Issued: 2015-05-01
Identifier: FSU_pmch_25676719, 10.1111/cdev.12344, PMC4428950, 25676719, 25676719
Format: Citation

Title: Depressive symptoms, thyroid hormone and autoimmunity in a population-based cohort from Sardinia.
Creator: Delitala, Alessandro P, Terracciano, Antonio, Fiorillo, Edoardo, Orrù, Valeria, Schlessinger, David, Cucca, Francesco
Abstract/Description: To evaluate the association between depressive symptoms and thyroid autoimmunity, and the effect of thyroid hormone on the risk of depression. We included 3138 individuals from SardiNIA project, none of whom was taking thyroid medication and antidepressants. Thyrotropin (TSH), free thyroxine (FT4), and antibodies against thyroperoxidase (TPOAb) were measured in all the sample. Depressive symptoms were assessed with Center for Epidemiologic Studies Depression Scale (CES-D). We found no...
Show moreTo evaluate the association between depressive symptoms and thyroid autoimmunity, and the effect of thyroid hormone on the risk of depression. We included 3138 individuals from SardiNIA project, none of whom was taking thyroid medication and antidepressants. Thyrotropin (TSH), free thyroxine (FT4), and antibodies against thyroperoxidase (TPOAb) were measured in all the sample. Depressive symptoms were assessed with Center for Epidemiologic Studies Depression Scale (CES-D). We found no association between TPOAb and depressive symptoms and no linear association between TSH or FT4 levels and depressive symptoms. However, individuals in the lowest and highest FT4 quintiles showed a higher CES-D score compared to individuals in the middle quintile. In addition, participants in the lowest and highest FT4 quintiles had an increased risk of CES-D≥16 with odds ratios of 1.44 (95% CI=1.09-1.89) and 1.33 (95% CI=1.01-1.77), respectively. Cross-sectional design of the study. A U-shaped relation was found between FT4 and depressive symptoms: compared to average FT4 values, both high and low thyroid function was associated with more depressive symptoms. Further studies are necessary to determine the exact cause-effect relation of this association.
Show less
Date Issued: 2016-02-01
Identifier: FSU_pmch_26655116, 10.1016/j.jad.2015.11.019, PMC4715961, 26655116, 26655116, S0165-0327(15)30912-5
Format: Citation

Title: Augmenting antidepressant medication treatment of depressed women with emotionally focused therapy for couples: a randomized pilot study..
Creator: Denton, Wayne H, Wittenborn, Andrea K, Golden, Robert N
Abstract/Description: This is the first study to evaluate adding emotionally focused therapy for couples (EFT) to antidepressant medication in the treatment of women with major depressive disorder and comorbid relationship discord. Twenty-four women and their male partners were randomized to 6 months of medication management alone (MM) or MM augmented with EFT (MM + EFT). MM followed the Texas Medication Algorithm Project guidelines. Fifteen EFT sessions were delivered following the EFT treatment manual. The...
Show moreThis is the first study to evaluate adding emotionally focused therapy for couples (EFT) to antidepressant medication in the treatment of women with major depressive disorder and comorbid relationship discord. Twenty-four women and their male partners were randomized to 6 months of medication management alone (MM) or MM augmented with EFT (MM + EFT). MM followed the Texas Medication Algorithm Project guidelines. Fifteen EFT sessions were delivered following the EFT treatment manual. The primary outcome was severity of depressive symptoms (assessed by the 30-item Inventory of Depressive Symptomatology-Clinician Rated version [IDS-C(30) ] administrated by evaluators blinded to cell assignment). Secondary outcome was relationship quality as assessed by the Quality of Marriage Index. Results from assessments at intake, termination, and two posttreatment follow-ups were analyzed using growth analysis techniques. IDS-C(30) scores improved over 6 months of treatment, regardless of the treatment assignment, and women receiving MM + EFT experienced significantly more improvement in relationship quality compared with women in MM. Because relationship discord after depression treatment predicts worse outcome, interventions improving relationship quality may reduce depression relapse and recurrence. Testing this hypothesis in larger samples with longer follow-up could contribute to knowledge on the mechanisms involved in determining the course of depressive illness.
Show less
Date Issued: 2012-06-01
Identifier: FSU_pmch_22765322, 10.1111/j.1752-0606.2012.00291.x, PMC4103029, 22765322, 22765322
Format: Citation

Title: Are new generations of female college-student populations meeting calcium requirements: comparison of American and Croatian female students..
Creator: Douglas, Crystal C, Rumbak, Ivana, Barić, Irena Colić, Kovačina, Marinela, Piasek, Martina, Ilich, Jasminka Z
Abstract/Description: We compared calcium (Ca) sources and intake, as well as multivitamin/mineral supplement use between female students with nutrition/health background and those from general-student-populations. 314 participants 18-37 y, including 57 African-Americans and 54 Caucasian-Americans recruited from Nutrition and/or other Health Sciences departments (NHS), and 100 African-American and 103 Croatian women representing general-student-population (GSP), completed food frequency questionnaire assessing...
Show moreWe compared calcium (Ca) sources and intake, as well as multivitamin/mineral supplement use between female students with nutrition/health background and those from general-student-populations. 314 participants 18-37 y, including 57 African-Americans and 54 Caucasian-Americans recruited from Nutrition and/or other Health Sciences departments (NHS), and 100 African-American and 103 Croatian women representing general-student-population (GSP), completed food frequency questionnaire assessing their usual Ca intake and supplement use. NHS populations met recommendations and consumed significantly more Ca, particularly from dairy sources, and were more likely to take supplements than GSP groups, suggesting that health education may influence Ca intake.
Show less
Date Issued: 2010-06-01
Identifier: FSU_pmch_22254044, 10.3390/nu2060599, PMC3257667, 22254044, 22254044, nu2060599
Format: Citation

Title: Psychoneurometric operationalization of threat sensitivity: Relations with clinical symptom and physiological response criteria..
Creator: Yancey, James R, Venables, Noah C, Patrick, Christopher J
Abstract/Description: The National Institute of Mental Health's Research Domain Criteria (RDoC) initiative calls for the incorporation of neurobiological approaches and findings into conceptions of mental health problems through a focus on biobehavioral constructs investigated across multiple domains of measurement (units of analysis). Although the constructs in the RDoC system are characterized in "process terms" (i.e., as functional concepts with brain and behavioral referents), these constructs can also be...
Show moreThe National Institute of Mental Health's Research Domain Criteria (RDoC) initiative calls for the incorporation of neurobiological approaches and findings into conceptions of mental health problems through a focus on biobehavioral constructs investigated across multiple domains of measurement (units of analysis). Although the constructs in the RDoC system are characterized in "process terms" (i.e., as functional concepts with brain and behavioral referents), these constructs can also be framed as dispositions (i.e., as dimensions of variation in biobehavioral functioning across individuals). Focusing on one key RDoC construct, acute threat or "fear," the current article illustrates a construct-oriented psychoneurometric strategy for operationalizing this construct in individual difference terms-as threat sensitivity (THT+). Utilizing data from 454 adult participants, we demonstrate empirically that (a) a scale measure of THT+ designed to tap general fear/fearlessness predicts effectively to relevant clinical problems (i.e., fear disorder symptoms), (b) this scale measure shows reliable associations with physiological indices of acute reactivity to aversive visual stimuli, and (c) a cross-domain factor reflecting the intersection of scale and physiological indicators of THT+ predicts effectively to both clinical and neurophysiological criterion measures. Results illustrate how the psychoneurometric approach can be used to create a dimensional index of a biobehavioral trait construct, in this case THT+, which can serve as a bridge between phenomena in domains of psychopathology and neurobiology. Implications and future directions are discussed with reference to the RDoC initiative and existing report-based conceptions of psychological traits.
Show less
Date Issued: 2016-03-01
Identifier: FSU_pmch_26877132, 10.1111/psyp.12512, PMC4756387, 26877132, 26877132
Format: Citation

Title: Is Insomnia Lonely? Exploring Thwarted Belongingness as an Explanatory Link between Insomnia and Suicidal Ideation in a Sample of South Korean University Students.
Creator: Chu, Carol, Hom, Melanie A, Rogers, Megan L, Ringer, Fallon B, Hames, Jennifer L, Suh, Sooyeon, Joiner, Thomas E
Abstract/Description: Suicide is a serious public health problem, and suicide rates are particularly high in South Korea. Insomnia has been identified as a risk factor for suicidal ideation; however, little is known about the mechanisms accounting for this relationship in this population. Based on the premise that insomnia can be lonely (e.g., being awake when everyone else is asleep), the purpose of this study was to examine whether greater insomnia severity would be associated with higher levels of thwarted...
Show moreSuicide is a serious public health problem, and suicide rates are particularly high in South Korea. Insomnia has been identified as a risk factor for suicidal ideation; however, little is known about the mechanisms accounting for this relationship in this population. Based on the premise that insomnia can be lonely (e.g., being awake when everyone else is asleep), the purpose of this study was to examine whether greater insomnia severity would be associated with higher levels of thwarted belongingness and suicidal ideation, and whether thwarted belongingness would mediate the relationship between insomnia and suicidal ideation. Predictions were tested in a sample of 552 South Korean young adults who completed self-report measures of insomnia severity, suicidal ideation, and thwarted belongingness. Greater insomnia symptom severity was significantly and positively associated with thwarted belongingness and suicidal ideation. Mediation analyses revealed that thwarted belongingness significantly accounted for the relationship between insomnia severity and suicidal ideation. These findings highlight the potential importance of monitoring and therapeutically impacting insomnia and thwarted belongingness to help reduce suicide risk.
Show less
Date Issued: 2016-05-15
Identifier: FSU_pmch_26857060, 10.5664/jcsm.5784, PMC4865549, 26857060, 26857060, jc-00384-15
Format: Citation

Title: Multisubstance Use Among Treatment-Seeking Smokers: Synergistic Effects of Coping Motives for Cannabis and Alcohol Use and Social Anxiety/Depressive Symptoms..
Creator: Foster, Dawn W, Buckner, Julia D, Schmidt, Norman B, Zvolensky, Michael J
Abstract/Description: This study examined the impact of coping motives for cannabis and alcohol use on the relation between social anxiety/depressive symptoms and severity of substance use for alcohol, tobacco, and cannabis among treatment-seeking smokers who also use cannabis and alcohol. The sample included 197 daily cigarette smokers (MAge 34.81 years, SD = 13.43) who reported using cannabis and alcohol. Hierarchical multiple regression analyses were conducted wherein separate models were constructed for each...
Show moreThis study examined the impact of coping motives for cannabis and alcohol use on the relation between social anxiety/depressive symptoms and severity of substance use for alcohol, tobacco, and cannabis among treatment-seeking smokers who also use cannabis and alcohol. The sample included 197 daily cigarette smokers (MAge 34.81 years, SD = 13.43) who reported using cannabis and alcohol. Hierarchical multiple regression analyses were conducted wherein separate models were constructed for each dependent variable. Among individuals with higher social anxiety, alcohol coping motives were associated with heavier drinking, and this was more pronounced among those low in depressive symptoms. Similarly, those at greater risk for nicotine dependence were anxious individuals with lower depressive symptoms who endorse coping-oriented motives for using cannabis. Further, among those with higher social anxiety, cannabis coping motives were associated with marginally greater drinking, particularly for those high in depressive symptoms. The present findings support the perspective that among multisubstance users, the interplay between social anxiety, depressive symptoms, and coping-oriented motives for using one substance (e.g., cannabis or alcohol) may pose difficulties in refraining from other substances (e.g., tobacco). This observation highlights the importance of tailoring multisubstance treatments to specific needs of multiusers for whom single-substance interventions may be less effective. Findings also support previous work exploring the benefits of concurrently treating co-occurring substance use and lend credence to the perspective that motivation to use substances for coping reasons is of central theoretical and clinical relevance.
Show less
Date Issued: 2016-01-28
Identifier: FSU_pmch_26846421, 10.3109/10826084.2015.1082596, PMC4755824, 26846421, 26846421
Format: Citation

Title: Sustained smoking abstinence is associated with reductions in smoking-specific experiential avoidance among treatment-seeking smokers.
Creator: Farris, Samantha G, DiBello, Angelo M, Heggeness, Luke F, Reitzel, Lorraine R, Vidrine, Damon J, Schmidt, Norman B, Zvolensky, Michael J
Abstract/Description: Smoking-specific experiential avoidance is related to the maintenance of cigarette smoking. However, it is unclear whether sustained smoking abstinence is associated with subsequent reductions in smoking-specific experiential avoidance. Daily smokers (n = 149) underwent a cessation attempt in the context of a 4-session smoking cessation treatment trial. Participants provided biochemical verification of smoking status at 1 week, 2 weeks, and 1 Month post-quit day. Smoking-specific experiential...
Show moreSmoking-specific experiential avoidance is related to the maintenance of cigarette smoking. However, it is unclear whether sustained smoking abstinence is associated with subsequent reductions in smoking-specific experiential avoidance. Daily smokers (n = 149) underwent a cessation attempt in the context of a 4-session smoking cessation treatment trial. Participants provided biochemical verification of smoking status at 1 week, 2 weeks, and 1 Month post-quit day. Smoking-specific experiential avoidance was assessed per the Avoidance and Inflexibility Scale (AIS) - the total score and two factor scores were examined at 1 Month post-quit day as a function of abstinence status. Two path models were conducted and included participant sex, treatment condition, and pre-cessation nicotine dependence, smoking-specific experiential avoidance, and presence of emotional disorders as covariates. After adjusting for covariates, sustained smoking abstinence was associated with a reduction in the AIS total score at Month 1 post-quit (β = -.45, p < .001). Sustained smoking abstinence was associated with reductions across both facets of experiential avoidance -- smoking-related thoughts and feelings (β = -.44, p < .001) and internal bodily sensations (β = -.41, p < .001). Biochemical verification of smoking status was confirmed only at three time points post-quit day, and continued abstinence throughout the one-month post-quitting period is not fully known. Sustained smoking abstinence may contribute to reductions in smoking-specific experiential avoidance. Findings add to the research documenting the relevance of experiential avoidance in various processes of smoking (including smoking abstinence).
Show less
Date Issued: 2016-06-01
Identifier: FSU_pmch_26773342, 10.1016/j.jbtep.2015.12.003, PMC4755816, 26773342, 26773342, S0005-7916(15)30047-1
Format: Citation

Title: Incremental validity of the episode size criterion in binge-eating definitions: An examination in women with purging syndromes..
Creator: Forney, K Jean, Bodell, Lindsay P, Haedt-Matt, Alissa A, Keel, Pamela K
Abstract/Description: Of the two primary features of binge eating, loss of control (LOC) eating is well validated while the role of eating episode size is less clear. Given the ICD-11 proposal to eliminate episode size from the binge-eating definition, the present study examined the incremental validity of the size criterion, controlling for LOC. Interview and questionnaire data come from four studies of 243 women with bulimia nervosa (n = 141) or purging disorder (n = 102). Hierarchical linear regression tested...
Show moreOf the two primary features of binge eating, loss of control (LOC) eating is well validated while the role of eating episode size is less clear. Given the ICD-11 proposal to eliminate episode size from the binge-eating definition, the present study examined the incremental validity of the size criterion, controlling for LOC. Interview and questionnaire data come from four studies of 243 women with bulimia nervosa (n = 141) or purging disorder (n = 102). Hierarchical linear regression tested if the largest reported episode size, coded in kilocalories, explained additional variance in eating disorder features, psychopathology, personality traits, and impairment, holding constant LOC eating frequency, age, and body mass index (BMI). Analyses also tested if episode size moderated the association between LOC eating and these variables. Holding LOC constant, episode size explained significant variance in disinhibition, trait anxiety, and eating disorder-related impairment. Episode size moderated the association of LOC eating with purging frequency and depressive symptoms, such that in the presence of larger eating episodes, LOC eating was more closely associated with these features. Neither episode size nor its interaction with LOC explained additional variance in BMI, hunger, restraint, shape concerns, state anxiety, negative urgency, or global functioning. Taken together, results support the incremental validity of the size criterion, in addition to and in combination with LOC eating, for defining binge-eating episodes in purging syndromes. Future research should examine the predictive validity of episode size in both purging and nonpurging eating disorders (e.g., binge eating disorder) to inform nosological schemes. © 2016 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:651-662).
Show less
Date Issued: 2016-07-01
Identifier: FSU_pmch_26841103, 10.1002/eat.22508, PMC4942344, 26841103, 26841103
Format: Citation

Title: Decomposing fear perception: A combination of psychophysics and neurometric modeling of fear perception..
Creator: Forscher, Emily C, Zheng, Yan, Ke, Zijun, Folstein, Jonathan, Li, Wen
Abstract/Description: Emotion perception is known to involve multiple operations and waves of analysis, but specific nature of these processes remains poorly understood. Combining psychophysical testing and neurometric analysis of event-related potentials (ERPs) in a fear detection task with parametrically varied fear intensities (N=45), we sought to elucidate key processes in fear perception. Building on psychophysics marking fear perception thresholds, our neurometric model fitting identified several putative...
Show moreEmotion perception is known to involve multiple operations and waves of analysis, but specific nature of these processes remains poorly understood. Combining psychophysical testing and neurometric analysis of event-related potentials (ERPs) in a fear detection task with parametrically varied fear intensities (N=45), we sought to elucidate key processes in fear perception. Building on psychophysics marking fear perception thresholds, our neurometric model fitting identified several putative operations and stages: four key processes arose in sequence following face presentation - fear-neutral categorization (P1 at 100ms), fear detection (P300 at 320ms), valuation (early subcomponent of the late positive potential/LPP at 400-500ms) and conscious awareness (late subcomponent LPP at 500-600ms). Furthermore, within-subject brain-behavior association suggests that initial emotion categorization was mandatory and detached from behavior whereas valuation and conscious awareness directly impacted behavioral outcome (explaining 17% and 31% of the total variance, respectively). The current study thus reveals the chronometry of fear perception, ascribing psychological meaning to distinct underlying processes. The combination of early categorization and late valuation of fear reconciles conflicting (categorical versus dimensional) emotion accounts, lending support to a hybrid model. Importantly, future research could specifically interrogate these psychological processes in various behaviors and psychopathologies (e.g., anxiety and depression).
Show less
Date Issued: 2016-10-01
Identifier: FSU_pmch_27546075, 10.1016/j.neuropsychologia.2016.08.018, PMC5075256, 27546075, 27546075, S0028-3932(16)30310-4
Format: Citation

Department of Psychology (43)	+ -
Department of Behavioral Sciences and Social Medicine (12)	+ -
Florida Learning Disability Research Center (11)	+ -
Department of Biomedical Sciences (6)	+ -
Department of Family and Child Sciences (4)	+ -

Department of Statistics (4)	+ -
Department of Chemistry and Biochemistry (2)	+ -
Department of Geriatrics (2)	+ -
Department of Nutrition, Food and Exercise Sciences (2)	+ -
Department of Sociology (2)	+ -
School of Communication Science and Disorders (2)	+ -
College of Nursing (1)	+ -
Department of Clinical Sciences (1)	+ -
Department of Educational Psychology and Learning Systems (1)	+ -
Department of Geography (1)	+ -
Department of Scientific Computing (1)	+ -
Institute of Molecular Biophysics (1)	+ -

Humans (92)	+ -
Female (82)	+ -
Male (69)	+ -
Young Adult (48)	+ -
Middle Aged (42)	+ -

Adolescent (32)	+ -
Aged (25)	+ -
Child (12)	+ -
Cross-Sectional Studies (12)	+ -
Surveys and Questionnaires (12)	+ -
Risk Factors (9)	+ -
Smoking/psychology (9)	+ -
Aged, 80 and over (8)	+ -
Depression/psychology (8)	+ -
Interpersonal Relations (8)	+ -
Smoking Cessation/psychology (8)	+ -
Tobacco Use Disorder/psychology (8)	+ -
Self Report (7)	+ -
Models, Psychological (6)	+ -
Prospective Studies (6)	+ -
Child, Preschool (5)	+ -
Motivation (5)	+ -
Reading (5)	+ -
Stress, Psychological/psychology (5)	+ -
Suicidal Ideation (5)	+ -
Tobacco Use Disorder/therapy (5)	+ -
United States (5)	+ -
Age Factors (4)	+ -
Animals (4)	+ -

text (92)	+ -
journal article (84)	+ -

Search In

Pages

Pages

Sort Results By:

Narrow results by:

Collection

Topical Subject

Genre

Type of Resource

Language

Creator

Found In

Owner