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Protein Allostery and Conformational Dynamics.
Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors.
Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas system.
Structure of an E. coli integral membrane sulfurtransferase and its structural transition upon SCN(-) binding defined by EPR-based hybrid method.
ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and Are Required for Optimal Production of Infectious Progeny Viruses.
DNA Interactions Probed by Hydrogen-Deuterium Exchange (HDX) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Confirm External Binding Sites on the Minichromosomal Maintenance (MCM) Helicase.
Prediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling
Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.
DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation.
14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels.
Semiclosed Conformations of the Ligand-Binding Domains of NMDA Receptors during Stationary Gating.
Regulated large-scale nucleosome density patterns and precise nucleosome positioning correlate with V(D)J recombination.
Protein folding, binding, and droplet formation in cell-like conditions.
Enhanced troponin I binding explains the functional changes produced by the hypertrophic cardiomyopathy mutation A8V of cardiac troponin C.
Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.
Mcm10 coordinates the timely assembly and activation of the replication fork helicase.
LARP6 Meets Collagen mRNA
Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis.
Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane.
Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.
Dpb11 protein helps control assembly of the Cdc45·Mcm2-7·GINS replication fork helicase.
Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase.
DNA damage checkpoints inhibit mitotic exit by two different mechanisms.
Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs
Allosteric activation of SENP1 by SUMO1 β-grasp domain involves a dock-and-coalesce mechanism.
Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs.
potential molecular pathogenesis of cardiac/laterality defects in Oculo-Facio-Cardio-Dental syndrome.
transcription factor YY1 is a novel substrate for Aurora B kinase at G2/M transition of the cell cycle.