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Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs
LARP6 Meets Collagen mRNA
Nonmuscle myosin-dependent synthesis of type I collagen.
novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.
novel role of vimentin filaments
RNA protein interactions governing expression of the most abundant protein in human body, type I collagen.
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs.
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis.
Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo.