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Title: 參宮の栞: Sangu no shiori.
Creator: 神宮神部署
Abstract/Description: This book provides a detailed description of worship services at Shinto Shrine (Ise shrine) in Ujyamada City (currently the city is named Ise-shi). In the book, general and conscious attitudes, formal worship, the structure of the Shrine, music and performance, festivals, funeral and other services are described and explained. There are also time tables, visitor statistics, and a brief city map.
Identifier: FSU_MSS_1989009_B22_F9_02
Format: Document (PDF)

Title: Φ-Value Analysis of Symfoil-4T.
Creator: Sutherland, Mason A., Department of Biological Science
Abstract/Description: A critical consideration in the process of de novo protein architecture design and protein evolution is the folding pathway and behavior a protein undertakes in transitioning to its functional tertiary structure. Of particular interest is a cryptic element within protein primary structure that enables an efficient folding pathway, and is postulated to be a heritable element in the evolution of protein architecture, the "folding nucleus" (FN). However, almost nothing is known regarding how the...
Show moreA critical consideration in the process of de novo protein architecture design and protein evolution is the folding pathway and behavior a protein undertakes in transitioning to its functional tertiary structure. Of particular interest is a cryptic element within protein primary structure that enables an efficient folding pathway, and is postulated to be a heritable element in the evolution of protein architecture, the "folding nucleus" (FN). However, almost nothing is known regarding how the FN changes as simpler peptide motifs join to form more complex polypeptides. To this effect, the structure and folding properties of foldable intermediates along the evolutionary trajectory of the β-trefoil protein type were tested. This study specifically used and compared data from Symfoil-4T (an engineered β-trefoil protein) to several mutants to show that the FN is acquired during gene fusion events, incorporating novel turn structure generated by gene fusion. Furthermore, the FN of β-trefoils are adjusted by circular permutation in response to destabilizing functional mutations to allow the survival of FN (which is made possible by the intrinsic C3 cyclic symmetry of β-trefoil architecture) identifying a selective advantage that helps explain extant cyclic structural symmetry in the proteome.
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Date Issued: 2015
Identifier: FSU_migr_uhm-0453
Format: Thesis

Title: π Berry phase and Zeeman splitting of Weyl semimetal TaP.
Creator: Hu, J, Liu, J Y, Graf, D, Radmanesh, S M A, Adams, D J, Chuang, A, Wang, Y, Chiorescu, I, Wei, J, Spinu, L, Mao, Z Q
Abstract/Description: The recent breakthrough in the discovery of Weyl fermions in monopnictide semimetals provides opportunities to explore the exotic properties of relativistic fermions in condensed matter. The chiral anomaly-induced negative magnetoresistance and π Berry phase are two fundamental transport properties associated with the topological characteristics of Weyl semimetals. Since monopnictide semimetals are multiple-band systems, resolving clear Berry phase for each Fermi pocket remains a challenge....
Show moreThe recent breakthrough in the discovery of Weyl fermions in monopnictide semimetals provides opportunities to explore the exotic properties of relativistic fermions in condensed matter. The chiral anomaly-induced negative magnetoresistance and π Berry phase are two fundamental transport properties associated with the topological characteristics of Weyl semimetals. Since monopnictide semimetals are multiple-band systems, resolving clear Berry phase for each Fermi pocket remains a challenge. Here we report the determination of Berry phases of multiple Fermi pockets of Weyl semimetal TaP through high field quantum transport measurements. We show our TaP single crystal has the signatures of a Weyl state, including light effective quasiparticle masses, ultrahigh carrier mobility, as well as negative longitudinal magnetoresistance. Furthermore, we have generalized the Lifshitz-Kosevich formula for multiple-band Shubnikov-de Haas (SdH) oscillations and extracted the Berry phases of π for multiple Fermi pockets in TaP through the direct fits of the modified LK formula to the SdH oscillations. In high fields, we also probed signatures of Zeeman splitting, from which the Landé g-factor is extracted.
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Date Issued: 2016-01-04
Identifier: FSU_pmch_26726050, 10.1038/srep18674, PMC4698660, 26726050, 26726050, srep18674
Format: Citation

Title: δ/ω-Plectoxin-Pt1a: an excitatory spider toxin with actions on both Ca(2+) and Na(+) channels..
Creator: Zhou, Yi, Zhao, Mingli, Fields, Gregg B, Wu, Chun-Fang, Branton, W Dale
Abstract/Description: The venom of spider Plectreurys tristis contains a variety of peptide toxins that selectively target neuronal ion channels. O-palmitoylation of a threonine or serine residue, along with a characteristic and highly constrained disulfide bond structure, are hallmarks of a family of toxins found in this venom. Here, we report the isolation and characterization of a new toxin, δ/ω-plectoxin-Pt1a, from this spider venom. It is a 40 amino acid peptide containing an O-palmitoylated Ser-39. Analysis...
Show moreThe venom of spider Plectreurys tristis contains a variety of peptide toxins that selectively target neuronal ion channels. O-palmitoylation of a threonine or serine residue, along with a characteristic and highly constrained disulfide bond structure, are hallmarks of a family of toxins found in this venom. Here, we report the isolation and characterization of a new toxin, δ/ω-plectoxin-Pt1a, from this spider venom. It is a 40 amino acid peptide containing an O-palmitoylated Ser-39. Analysis of δ/ω-plectoxin-Pt1a cDNA reveals a small precursor containing a secretion signal sequence, a 14 amino acid N-terminal propeptide, and a C-terminal amidation signal. The biological activity of δ/ω-plectoxin-Pt1a is also unique. It preferentially blocks a subset of Ca(2+) channels that is apparently not required for neurotransmitter release; decreases threshold for Na(+) channel activation; and slows Na(+) channel inactivation. As δ/ω-plectoxin-Pt1a enhances synaptic transmission by prolonging presynaptic release of neurotransmitter, its effects on Na(+) and Ca(2+) channels may act synergistically to sustain the terminal excitability.
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Date Issued: 2013-05-14
Identifier: FSU_pmch_23691198, 10.1371/journal.pone.0064324, PMC3653879, 23691198, 23691198, PONE-D-13-04611
Format: Citation

Title: δ/ω-Plectoxin-Pt1a: An Excitatory Spider Toxin with Actions on both Ca(2+) and Na(+) Channels.
Creator: Zhou, Yi, Zhao, Mingli, Fields, Gregg B., Wu, Chun-Fang, Branton, W.
Abstract/Description: The venom of spider Plectreurys tristis contains a variety of peptide toxins that selectively target neuronal ion channels. O-palmitoylation of a threonine or serine residue, along with a characteristic and highly constrained disulfide bond structure, are hallmarks of a family of toxins found in this venom. Here, we report the isolation and characterization of a new toxin, δ/ω-plectoxin-Pt1a, from this spider venom. It is a 40 amino acid peptide containing an O-palmitoylated Ser-39. Analysis...
Show moreThe venom of spider Plectreurys tristis contains a variety of peptide toxins that selectively target neuronal ion channels. O-palmitoylation of a threonine or serine residue, along with a characteristic and highly constrained disulfide bond structure, are hallmarks of a family of toxins found in this venom. Here, we report the isolation and characterization of a new toxin, δ/ω-plectoxin-Pt1a, from this spider venom. It is a 40 amino acid peptide containing an O-palmitoylated Ser-39. Analysis of δ/ω-plectoxin-Pt1a cDNA reveals a small precursor containing a secretion signal sequence, a 14 amino acid N-terminal propeptide, and a C-terminal amidation signal. The biological activity of δ/ω-plectoxin-Pt1a is also unique. It preferentially blocks a subset of Ca(2+) channels that is apparently not required for neurotransmitter release; decreases threshold for Na(+) channel activation; and slows Na(+) channel inactivation. As δ/ω-plectoxin-Pt1a enhances synaptic transmission by prolonging presynaptic release of neurotransmitter, its effects on Na(+) and Ca(2+) channels may act synergistically to sustain the terminal excitability.
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Date Issued: 2013
Identifier: FSU_migr_biomed_faculty_publications-0044
Format: Citation

Title: βTRCP: Linking Circadian Rhythms and Metabolism.
Creator: Sweeney, Megan C., Department of Biomedical Sciences
Abstract/Description: Shifts in circadian rhythms, like in shift work or jet lag, have been shown to increase the risk of many metabolic disorders. Therefore, it is not surprising that many genes involved in the circadian clock mechanism have demonstrated a regulatory role in metabolism. It has been shown that E3 ubiquitin ligases can influence metabolism as well. In initial studies, my lab created a knockout of two E3 ubiquitin ligases thought to be essential to the clock, βTRCP1/2, in a mouse model in order to...
Show moreShifts in circadian rhythms, like in shift work or jet lag, have been shown to increase the risk of many metabolic disorders. Therefore, it is not surprising that many genes involved in the circadian clock mechanism have demonstrated a regulatory role in metabolism. It has been shown that E3 ubiquitin ligases can influence metabolism as well. In initial studies, my lab created a knockout of two E3 ubiquitin ligases thought to be essential to the clock, βTRCP1/2, in a mouse model in order to study the proteasomal degradation machinery in mammals. Upon characterizing the circadian phenotype of this mouse, we noticed an unprecedented, metabolic phenotype after deletion of these vital ligases. These novel mutant mice lose over 30% of their body weight within 5 days while still maintaining an eating and drinking regime similar to wild-type mice. In this project, in vivo and sequence analysis studies aimed to look further into the causes of this phenomenon and the molecular mechanisms underlying them.
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Date Issued: 2015
Identifier: FSU_migr_uhm-0455
Format: Thesis

Title: ¿Preguntas?.
Creator: Stephen M. Quintero, MD
Identifier: FSU_3694860714_82911
Format: Document (PDF)

Title: ¡En la sombra!.
Creator: Ann Sheddan
Identifier: FSU_9432595714_79711
Format: Document (PDF)

Title: Zymosan Fungal Infection Induces Nucleosome Redistributions During the Innate Immune Response.
Creator: Gruder, Olivia, Dennis, Jonathan, Department of Biological Science
Abstract/Description: Chromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component the fungal cell wall that induces an innate immune response. After...
Show moreChromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component the fungal cell wall that induces an innate immune response. After THP1 were treated with zymosan, we hypothesized that the fungal infection would initiate an inflammatory response by altering nucleosome redistribution and/or altering chromatin structure in a time dependent manner. Based on previous results that showed rapid, widespread, transient changes in nucleosome distribution in the innate immune response, we chose to look at multiple time points at high temporal resolution: 0 (control), 20', 40', 60', 80', 100', 2h, 3h, 4h and 12h. We measured nucleosome distribution at each of these time points at hundreds of genes transcription start sites involved in the immune response. nucleosome distribution changes in the innate immune response to fungal infection.
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Date Issued: 2014
Identifier: FSU_migr_uhm-0312
Format: Thesis

Title: Zymosan Fungal Infection Induces Necleosome Distributions During the Innate Immune Response on a Time Dependent Manner.
Creator: Gruder, Olivia, Department of Biological Sciences
Abstract/Description: Chromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage-like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component of the fungal cell wall that induces an innate immune response. After...
Show moreChromatin structure plays a critical role in the regulation of the human genome. An understanding of the role of chromatin structure and its relationship to gene regulation is critical to developing new strategies to prevent and treat diseases. We chose to investigate the anti-inflammatory response of human macrophage-like cell line (THP1) to Zymosan, in order to elucidate the regulation of chromatin. Zymosan is a component of the fungal cell wall that induces an innate immune response. After THP1 were treated with Zymosan, we hypothesized that the fungal infection would initiate an inflammatory response by altering nucleosome redistribution and/or altering chromatin structure in a time dependent manner. Based on previous results that showed rapid, widespread, transient changes in nucleosome distribution in the innate immune response, we chose to look at multiple time points at high temporal resolution: 0 (control), 20', 40', 60', 80', 100', 2h, 3h, 4h and 12h. We measured nucleosome distribution at each of these time points at hundreds of genes transcription start sites involved in the immune response. We saw the greatest changes in nucleosome positioning from 20 to 60 minutes, and it appeared that these changes were transient since they reverted back to their original after the 60-minute time point. These results support our prediction that all cells have the same nucleosome distributions during their resting states, but can be altered with the addition of an insult. In response to a stimulus, a biochemical "yawn" occurs to provide accessibility to genes needed to provide a response. The data indicates that widespread but transient changes occur to the entire genome upon response to an environmental stimulus.
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Date Issued: 2013
Identifier: FSU_migr_undergradresearch-0006
Format: Citation

Title: Zooarchaeological Remains from the 1998 Fewkes Site Excavations, Williamson County, Tennessee.
Creator: Peres, Tanya M.
Abstract/Description: The Fewkes site faunal assemblage, excavated as part of a Phase III data recovery project for the Tennessee Department of Transportation in 1998, was analyzed and evaluated in light of its potential to provide significant information about Middle Mississippian subsistence practices and environmental conditions of the area during the time of occupation. Specific goals of the analysis included: (1) defining the subsistence strategies and practices of the people that inhabited the site; (2)...
Show moreThe Fewkes site faunal assemblage, excavated as part of a Phase III data recovery project for the Tennessee Department of Transportation in 1998, was analyzed and evaluated in light of its potential to provide significant information about Middle Mississippian subsistence practices and environmental conditions of the area during the time of occupation. Specific goals of the analysis included: (1) defining the subsistence strategies and practices of the people that inhabited the site; (2) determining the relationship of the site to the surrounding ecological habitats; and (3) determining the seasonality of the site. Additionally, the Fewkes faunal assemblage was compared to animal exploitation practices as outlined for the Cumberland River drainage model of Mississippian period sites. The results of the analysis of selected contexts are presented here.
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Date Issued: 2010
Identifier: FSU_libsubv1_scholarship_submission_1453748255
Format: Citation

Title: Zooarchaeological Analysis of Faunal Remains Recovered from Totten Key (8DA3439) (SEAC Accession #2628), Biscayne National Park, Miami-Dade County Florida.
Creator: Peres, Tanya M., McLean, Emily
Abstract/Description: This is a report of the zooarchaeological analysis of faunal remains recovered as part of the excavations by archeologists with the Southeastern Archeological Center (SEAC) of the National Park Service at the Totten Key Site (8DA3439) on Totten Key, Miami-Dade County, Florida. This analysis was performed under the Southern Appalachian Cooperative Ecosystems Studies Unit (SA-CESU) Task Agreement Number (P14AC01652) under Cooperative Agreement Number P14AC00882 between the United States...
Show moreThis is a report of the zooarchaeological analysis of faunal remains recovered as part of the excavations by archeologists with the Southeastern Archeological Center (SEAC) of the National Park Service at the Totten Key Site (8DA3439) on Totten Key, Miami-Dade County, Florida. This analysis was performed under the Southern Appalachian Cooperative Ecosystems Studies Unit (SA-CESU) Task Agreement Number (P14AC01652) under Cooperative Agreement Number P14AC00882 between the United States Department of the Interior - The National Park Service/Southeast Archeological Center and Middle Tennessee State University (PI Tanya M. Peres, September 2014) (Appendix 1). The Project title is “Documenting Subsistence Strategies in the Southeast Using the National Park Service’s Archeological Resources.” In October 2015, the remainder of the zooarchaeological analysis and reporting was subcontracted by Middle Tennessee State University to Tanya M. Peres at Florida State University (FSU Project# 037433 | MTSU Award# 536858S).
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Date Issued: 2018-07-16
Identifier: FSU_libsubv1_scholarship_submission_1532019273_4d277f12, 10.17125/fsu.1532019273
Format: Citation

Title: Zooarchaeological Analysis of Faunal Remains Recovered from Sands Key #2 (8D2) (SEAC Accession #1930), Biscayne National Park, Miami-Dade County Florida.
Creator: Peres, Tanya M., McLean, Emily
Abstract/Description: This is a report of the zooarchaeological analysis of faunal remains recovered as part of the excavations by archeologists with the Southeastern Archeological Center of the National Park Service at the Sands Key #2 site (8DA2) (SEAC Acc #1930), located in the Biscayne National Park, Miami-Dade County, Florida. This analysis was performed under the Southern Appalachian Cooperative Ecosystems Studies Unit (SA-CESU) Task Agreement Number (P14AC01652) under Cooperative Agreement Number P14AC00882...
Show moreThis is a report of the zooarchaeological analysis of faunal remains recovered as part of the excavations by archeologists with the Southeastern Archeological Center of the National Park Service at the Sands Key #2 site (8DA2) (SEAC Acc #1930), located in the Biscayne National Park, Miami-Dade County, Florida. This analysis was performed under the Southern Appalachian Cooperative Ecosystems Studies Unit (SA-CESU) Task Agreement Number (P14AC01652) under Cooperative Agreement Number P14AC00882 between the United States Department of the Interior - The National Park Service/Southeast Archeological Center and Middle Tennessee State University (PI Tanya M. Peres, September 2014). The Project title is “Documenting Subsistence Strategies in the Southeast Using the National Park Service’s Archeological Resources.” In October 2015, the remainder of the zooarchaeological analysis and reporting was subcontracted by Middle Tennessee State University to Tanya M. Peres at Florida State University (FSU Project# 037433 | MTSU Award# 536858S). The Sands Key #2 faunal assemblage reported on here contains 9,812 specimens weighing 12,791.65 g. The data generated from the zooarchaeological analysis is detailed in this report. Preliminary interpretations about the use of aquatic resources by the Tequesta are offered.
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Date Issued: 2018-01-19
Identifier: FSU_libsubv1_scholarship_submission_1532018990_f2e488bf, 10.17125/fsu.1532018990
Format: Citation

Title: Zooarchaeological Analysis of a Multicomponent Shell-Bearing Site in Davidson County, Tennessee.
Creator: Peres, Tanya M., Deter-Wolf, Aaron, Myers, Gage A.
Abstract/Description: Site 40DV7 is one of several large shell-bearing sites located along the Cumberland River near Nashville which were heavily impacted by catastrophic flooding and looting activity during the spring of 2010. Emergency sampling and ongoing monitoring at 40DV7 since that time have identified deeply-stratified deposits spanning the Archaic through Mississippian periods. These deposits, and particularly the temporally-distinct shell midden components, may help inform our understanding of human...
Show moreSite 40DV7 is one of several large shell-bearing sites located along the Cumberland River near Nashville which were heavily impacted by catastrophic flooding and looting activity during the spring of 2010. Emergency sampling and ongoing monitoring at 40DV7 since that time have identified deeply-stratified deposits spanning the Archaic through Mississippian periods. These deposits, and particularly the temporally-distinct shell midden components, may help inform our understanding of human occupation, species interdependence, and environmental change along the Cumberland River over a period of more than 5000 years.
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Date Issued: 2012
Identifier: FSU_libsubv1_scholarship_submission_1453747339
Format: Citation

Title: Zn(II)-coordination modulated ligand photophysical processes – the development of fluorescent indicators for imaging biological Zn(II) ions.
Creator: Zhu, Lei, Yuan, Zhao, Simmons, J., Sreenath, Kesavapillai
Abstract/Description: Molecular photophysics and metal coordination chemistry are the two fundamental pillars that support the development of fluorescent cation indicators. In this article, we describe how Zn(II)-coordination alters various ligand-centered photophysical processes that are pertinent to developing Zn(II) indicators. The main aim is to show how small organic Zn(II) indicators work under the constraints of specific requirements, including Zn(II) detection range, photophysical requirements such as...
Show moreMolecular photophysics and metal coordination chemistry are the two fundamental pillars that support the development of fluorescent cation indicators. In this article, we describe how Zn(II)-coordination alters various ligand-centered photophysical processes that are pertinent to developing Zn(II) indicators. The main aim is to show how small organic Zn(II) indicators work under the constraints of specific requirements, including Zn(II) detection range, photophysical requirements such as excitation energy and emission color, temporal and spatial resolutions in a heterogeneous intracellular environment, and fluorescence response selectivity between similar cations such as Zn(II) and Cd(II). In the last section, the biological questions that fluorescent Zn(II) indicators help to answer are described, which have been motivating and challenging this field of research.
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Date Issued: 2014
Identifier: FSU_migr_chm_faculty_publications-0016, 10.1039/C4RA00354C
Format: Citation

Title: Zn And P Alloying Effect In Sub-rapidly Solidified Lafe11.6si1.4 Magnetocaloric Plates.
Creator: Jin, Pingxia, Li, Yuqiang, Dai, Yuting, Xu, Zhishuai, Song, Changjiang, Luo, Zhiping, Zhai, Qijie, Han, Ke, Zheng, Hongxing
Abstract/Description: The occupation mechanism and magnetic transition behavior of trace Zn and P alloying in the sub-rapidly solidified LaFe11.6Si1.4 magnetocaloric plates were investigated. The LaFe11.6Si1.4, LaFe11.6Si1.4Zn0.03, and LaFe11.6Si1.4P0.03 plates were fabricated using the centrifugal casting method in the present work. Experimental results showed that both Zn and P elements were distributed in the La5Si3 and LaFeSi phases during sub-rapid solidification. After annealed at 1373 K for 72 h, the LaFe11...
Show moreThe occupation mechanism and magnetic transition behavior of trace Zn and P alloying in the sub-rapidly solidified LaFe11.6Si1.4 magnetocaloric plates were investigated. The LaFe11.6Si1.4, LaFe11.6Si1.4Zn0.03, and LaFe11.6Si1.4P0.03 plates were fabricated using the centrifugal casting method in the present work. Experimental results showed that both Zn and P elements were distributed in the La5Si3 and LaFeSi phases during sub-rapid solidification. After annealed at 1373 K for 72 h, the LaFe11.6Si1.4 plate underwent a second-order magnetic transition, while both the LaFe11.6Si1.4Zn0.03 and LaFe11.6Si1.4P0.03 plates underwent a first-order transition. In combination with X-ray diffraction results, it was proposed that both Zn and P atoms prefer to enter the 96i site substituting for FeII/Si atoms according to the density-functional reconstruction of crystallographic structure. The Zn addition led to a slight decrease in magnetic entropy change from 7.0 to 5.9 J/(kgK), while the P addition strikingly enhanced this property to 31.4 J/(kgK) under a magnetic field change of 3 T. The effective refrigeration capacity of the annealed LaFe11.6Si1.4P0.03 plate reached 189.9 J/kg.
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Date Issued: Mon Apr 01 00:00:00 ED
Identifier: FSU_libsubv1_wos_000467637000049, 10.3390/met9040432
Format: Citation

Title: Zinc supplementation provides behavioral resiliency in a rat model of traumatic brain injury.
Creator: Cope, Elise C, Morris, Deborah R, Scrimgeour, Angus G, VanLandingham, Jacob W, Levenson, Cathy W
Abstract/Description: Depression, anxiety, and impairments in learning and memory are all associated with traumatic brain injury (TBI). Because of the strong link between zinc deficiency, depression, and anxiety, in both humans and rodent models, we hypothesized that dietary zinc supplementation prior to injury could provide behavioral resiliency to lessen the severity of these outcomes after TBI. Rats were fed a marginal zinc deficient (5 ppm), zinc adequate (30 ppm), or zinc supplemented (180 ppm) diet for 4...
Show moreDepression, anxiety, and impairments in learning and memory are all associated with traumatic brain injury (TBI). Because of the strong link between zinc deficiency, depression, and anxiety, in both humans and rodent models, we hypothesized that dietary zinc supplementation prior to injury could provide behavioral resiliency to lessen the severity of these outcomes after TBI. Rats were fed a marginal zinc deficient (5 ppm), zinc adequate (30 ppm), or zinc supplemented (180 ppm) diet for 4 weeks followed by a moderately-severe TBI using the well-established model of controlled cortical impact (CCI). Following CCI, rats displayed depression-like behaviors as measured by the 2-bottle saccharin preference test for anhedonia. Injury also resulted in evidence of stress and impairments in Morris water maze (MWM) performance compared to sham-injured controls. While moderate zinc deficiency did not worsen outcomes following TBI, rats that were fed the zinc supplemented diet for 4 weeks showed significantly attenuated increases in adrenal weight (p<0.05) as well as reduced depression-like behaviors (p<0.001). Supplementation prior to injury improved resilience such that there was not only significant improvements in cognitive behavior compared to injured rats fed an adequate diet (p<0.01), there were no significant differences between supplemented and sham-operated rats in MWM performance at any point in the 10-day trial. These data suggest a role for supplemental zinc in preventing cognitive and behavioral deficits associated with TBI.
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Date Issued: 2011-10-24
Identifier: FSU_pmch_21699908, 10.1016/j.physbeh.2011.06.007, PMC3506179, 21699908, 21699908, S0031-9384(11)00322-2
Format: Citation

Title: Zinc regulation of transcriptional activity during retinoic acid-induced neuronal differentiation.
Creator: Morris, Deborah R, Levenson, Cathy W
Abstract/Description: Zinc deficiency impairs the proliferation and differentiation of stem cells in the central nervous system that participate in neurogenesis. To examine the molecular mechanisms responsible for the role of this essential nutrient in neuronal precursor cells and neuronal differentiation, we identified zinc-dependent changes in the DNA-binding activity of zinc finger proteins and other transcription factors in proliferating human Ntera-2 neuronal precursor cells undergoing retinoic acid...
Show moreZinc deficiency impairs the proliferation and differentiation of stem cells in the central nervous system that participate in neurogenesis. To examine the molecular mechanisms responsible for the role of this essential nutrient in neuronal precursor cells and neuronal differentiation, we identified zinc-dependent changes in the DNA-binding activity of zinc finger proteins and other transcription factors in proliferating human Ntera-2 neuronal precursor cells undergoing retinoic acid-stimulated differentiation into a neuronal phenotype. We found that zinc deficiency altered binding activity of 28 transcription factors including retinoid X receptor (RXR) known to participate in neuronal differentiation. Alterations in zinc finger transcription factor activity were not simply the result of removal of zinc from these proteins during zinc deficiency, as the activity of other zinc-binding transcription factors such as the glucocorticoid receptor was increased by as much as twofold over zinc-adequate conditions, and nonzinc-binding transcription factors such as nuclear factor-1 and heat shock transcription factor-1 were increased by as much as fourfold over control. Western analysis did not detect significant decreases in total RXR protein abundance in neuronal precursors, suggesting that the decrease in DNA-binding activity was not simply the result of a reduction in RXR levels in neuronal precursor cells. Rather, use of a reporter gene construct containing retinoic acid response elements upstream from a luciferase coding sequence revealed that zinc deficiency results in decreased transcriptional activity of RXR and reductions in retinoic acid-mediated gene transcription during neuronal differentiation. These results show that zinc deficiency has implications for both developmental and adult neurogenesis.
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Date Issued: 2013-11-01
Identifier: FSU_pmch_24029070, 10.1016/j.jnutbio.2013.06.002, PMC3832953, 24029070, 24029070, S0955-2863(13)00126-5
Format: Citation

Title: Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival.
Creator: Hagler, Shaye, Department of Chemistry and Biochemistry
Abstract/Description: Mesenchymal stem cells (MSC) have a wide variety of promising clinical applications including the treatment of brain disorders and injury, cardiovascular disease, and cancer. To fully exploit their potential, we need a better understanding of the cellular and molecular mechanisms that govern stem cell division and survival. We have hypothesized that the essential trace element zinc regulates the proliferation and survival of rat and human bone marrow-derived MSC. Proliferation of MSC is...
Show moreMesenchymal stem cells (MSC) have a wide variety of promising clinical applications including the treatment of brain disorders and injury, cardiovascular disease, and cancer. To fully exploit their potential, we need a better understanding of the cellular and molecular mechanisms that govern stem cell division and survival. We have hypothesized that the essential trace element zinc regulates the proliferation and survival of rat and human bone marrow-derived MSC. Proliferation of MSC is impaired by zinc deficiency. For example, after 48h of zinc deficiency, proliferation was reduced by 50% (p
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Date Issued: 2013
Identifier: FSU_migr_uhm-0181
Format: Thesis

Title: Zinc Regulation of Bone Marrow-Derived Mesenchymal Stem Cell Neuronal Differentiation.
Creator: Faye, Sari, Department of Chemistry and Biochemistry
Abstract/Description: The multipotent ability of mesenchymal stem cells (MSC) to differentiate into a large variety of mature cell types gives them a high potential for use in a variety of therapeutic purposes. Recently, it was discovered that bone marrow derived MSC could be induced to take on a neuronal phenotype through the addition of cobalt chloride (CoCl2) to the growth media. It is also well known that the trace element zinc is vital for both neuronal proliferation and differentiation from neuronal...
Show moreThe multipotent ability of mesenchymal stem cells (MSC) to differentiate into a large variety of mature cell types gives them a high potential for use in a variety of therapeutic purposes. Recently, it was discovered that bone marrow derived MSC could be induced to take on a neuronal phenotype through the addition of cobalt chloride (CoCl2) to the growth media. It is also well known that the trace element zinc is vital for both neuronal proliferation and differentiation from neuronal precursor cells. Thus, this work tested the hypothesis that zinc plays a role in the differentiation of MSC into neurons. Secondly, because zinc is unable to enter or exit cells without the assistance of zinc transport proteins (ZnT), this work tested the hypothesis that two transport proteins, ZnT-1 and ZnT-4, would be regulated both by zinc and by treatment with cobalt. This work used both cell morphology and markers of neuronal differentiation (TuJ1 and neuronal specific enolase) to show that zinc deficiency (ZD) combined with CoCl2 treatment appeared to induce differentiation of rat MSC. Furthermore, the zinc transporters were differentially regulated such that ZnT-4 was increased on the cell membrane by zinc deficiency, while ZnT-1 levels at the membrane were highest in the combined zinc deficiency-cobalt treatment group. These data implicate zinc in the mechanisms associated with MSC function.
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Date Issued: 2013
Identifier: FSU_migr_uhm-0235
Format: Thesis

Title: Zinc in the central nervous system: From molecules to behavior..
Creator: Gower-Winter, Shannon D, Levenson, Cathy W
Abstract/Description: The trace metal zinc is a biofactor that plays essential roles in the central nervous system across the lifespan from early neonatal brain development through the maintenance of brain function in adults. At the molecular level, zinc regulates gene expression through transcription factor activity and is responsible for the activity of dozens of key enzymes in neuronal metabolism. At the cellular level, zinc is a modulator of synaptic activity and neuronal plasticity in both development and...
Show moreThe trace metal zinc is a biofactor that plays essential roles in the central nervous system across the lifespan from early neonatal brain development through the maintenance of brain function in adults. At the molecular level, zinc regulates gene expression through transcription factor activity and is responsible for the activity of dozens of key enzymes in neuronal metabolism. At the cellular level, zinc is a modulator of synaptic activity and neuronal plasticity in both development and adulthood. Given these key roles, it is not surprising that alterations in brain zinc status have been implicated in a wide array of neurological disorders including impaired brain development, neurodegenerative disorders such as Alzheimer's disease, and mood disorders including depression. Zinc has also been implicated in neuronal damage associated with traumatic brain injury, stroke, and seizure. Understanding the mechanisms that control brain zinc homeostasis is thus critical to the development of preventive and treatment strategies for these and other neurological disorders.
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Date Issued: 2012-05-01
Identifier: FSU_pmch_22473811, 10.1002/biof.1012, PMC3757551, 22473811, 22473811
Format: Citation

Title: Zinc and neurogenesis: making new neurons from development to adulthood..
Creator: Levenson, Cathy W, Morris, Deborah
Abstract/Description: Stem cell proliferation, neuronal differentiation, cell survival, and migration in the central nervous system are all important steps in the normal process of neurogenesis. These mechanisms are highly active during gestational and early neonatal brain development. Additionally, in select regions of the brain, stem cells give rise to new neurons throughout the human lifespan. Recent work has revealed key roles for the essential trace element zinc in the control of both developmental and adult...
Show moreStem cell proliferation, neuronal differentiation, cell survival, and migration in the central nervous system are all important steps in the normal process of neurogenesis. These mechanisms are highly active during gestational and early neonatal brain development. Additionally, in select regions of the brain, stem cells give rise to new neurons throughout the human lifespan. Recent work has revealed key roles for the essential trace element zinc in the control of both developmental and adult neurogenesis. Given the prevalence of zinc deficiency, these findings have implications for brain development, cognition, and the regulation of mood.
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Date Issued: 2011-03-01
Identifier: FSU_pmch_22332038, 10.3945/an.110.000174, PMC3065768, 22332038, 22332038, 000174
Format: Citation

Title: ZIKV AND DENV DIFFERENTIALLY PERTURB ISG15 DESPITE SIMILAR RESTRICTION BY INTERFERON.
Creator: Sherman, Allaura
Date Issued: 2016-04-15
Identifier: FSU_libsubv1_scholarship_submission_1461944782
Format: Thesis

Title: Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins.
Creator: Yoon, Ki-Jun, Song, Guang, Qian, Xuyu, Pan, Jianbo, Xu, Dan, Rho, Hee-Sool, Kim, Nam-Shik, Habela, Christa, Zheng, Lily, Jacob, Fadi, Zhang, Feiran, Lee, Emily M, Huang, Wei-Kai...
Show moreYoon, Ki-Jun, Song, Guang, Qian, Xuyu, Pan, Jianbo, Xu, Dan, Rho, Hee-Sool, Kim, Nam-Shik, Habela, Christa, Zheng, Lily, Jacob, Fadi, Zhang, Feiran, Lee, Emily M, Huang, Wei-Kai, Ringeling, Francisca Rojas, Vissers, Caroline, Li, Cui, Yuan, Ling, Kang, Koeun, Kim, Sunghan, Yeo, Junghoon, Cheng, Yichen, Liu, Sheng, Wen, Zhexing, Qin, Cheng-Feng, Wu, Qingfeng, Christian, Kimberly M, Tang, Hengli, Jin, Peng, Xu, Zhiheng, Qian, Jiang, Zhu, Heng, Song, Hongjun, Ming, Guo-Li
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Abstract/Description: Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact neurogenesis in vivo is not well understood. Here, by systematically introducing individual proteins encoded by ZIKV into the embryonic mouse cortex, we show that expression of ZIKV-NS2A, but not Dengue virus (DENV)-NS2A, leads to reduced proliferation and premature differentiation of radial glial cells and aberrant positioning of newborn...
Show moreZika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact neurogenesis in vivo is not well understood. Here, by systematically introducing individual proteins encoded by ZIKV into the embryonic mouse cortex, we show that expression of ZIKV-NS2A, but not Dengue virus (DENV)-NS2A, leads to reduced proliferation and premature differentiation of radial glial cells and aberrant positioning of newborn neurons. Mechanistically, in vitro mapping of protein-interactomes and biochemical analysis suggest interactions between ZIKA-NS2A and multiple adherens junction complex (AJ) components. Functionally, ZIKV-NS2A, but not DENV-NS2A, destabilizes the AJ complex, resulting in impaired AJ formation and aberrant radial glial fiber scaffolding in the embryonic mouse cortex. Similarly, ZIKA-NS2A, but not DENV-NS2A, reduces radial glial cell proliferation and causes AJ deficits in human forebrain organoids. Together, our results reveal pathogenic mechanisms underlying ZIKV infection in the developing mammalian brain.
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Date Issued: 2017-09-07
Identifier: FSU_pmch_28826723, 10.1016/j.stem.2017.07.014, PMC5600197, 28826723, 28826723, S1934-5909(17)30293-X
Format: Citation

Title: Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth.
Creator: Tang, Hengli, Hammack, Christy, Ogden, Sarah C, Wen, Zhexing, Qian, Xuyu, Li, Yujing, Yao, Bing, Shin, Jaehoon, Zhang, Feiran, Lee, Emily M, Christian, Kimberly M, Didier, Ruth...
Show moreTang, Hengli, Hammack, Christy, Ogden, Sarah C, Wen, Zhexing, Qian, Xuyu, Li, Yujing, Yao, Bing, Shin, Jaehoon, Zhang, Feiran, Lee, Emily M, Christian, Kimberly M, Didier, Ruth A, Jin, Peng, Song, Hongjun, Ming, Guo-Li
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Abstract/Description: The suspected link between infection by Zika virus (ZIKV), a re-emerging flavivirus, and microcephaly is an urgent global health concern. The direct target cells of ZIKV in the developing human fetus are not clear. Here we show that a strain of the ZIKV, MR766, serially passaged in monkey and mosquito cells efficiently infects human neural progenitor cells (hNPCs) derived from induced pluripotent stem cells. Infected hNPCs further release infectious ZIKV particles. Importantly, ZIKV infection...
Show moreThe suspected link between infection by Zika virus (ZIKV), a re-emerging flavivirus, and microcephaly is an urgent global health concern. The direct target cells of ZIKV in the developing human fetus are not clear. Here we show that a strain of the ZIKV, MR766, serially passaged in monkey and mosquito cells efficiently infects human neural progenitor cells (hNPCs) derived from induced pluripotent stem cells. Infected hNPCs further release infectious ZIKV particles. Importantly, ZIKV infection increases cell death and dysregulates cell-cycle progression, resulting in attenuated hNPC growth. Global gene expression analysis of infected hNPCs reveals transcriptional dysregulation, notably of cell-cycle-related pathways. Our results identify hNPCs as a direct ZIKV target. In addition, we establish a tractable experimental model system to investigate the impact and mechanism of ZIKV on human brain development and provide a platform to screen therapeutic compounds.
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Date Issued: 2016-05-05
Identifier: FSU_pmch_26952870, 10.1016/j.stem.2016.02.016, PMC5299540, 26952870, 26952870, S1934-5909(16)00106-5
Format: Citation

Title: Zika virus directly infects peripheral neurons and induces cell death.
Creator: Oh, Yohan, Zhang, Feiran, Wang, Yaqing, Lee, Emily M, Choi, In Young, Lim, Hotae, Mirakhori, Fahimeh, Li, Ronghua, Huang, Luoxiu, Xu, Tianlei, Wu, Hao, Li, Cui, Qin, Cheng-Feng,...
Show moreOh, Yohan, Zhang, Feiran, Wang, Yaqing, Lee, Emily M, Choi, In Young, Lim, Hotae, Mirakhori, Fahimeh, Li, Ronghua, Huang, Luoxiu, Xu, Tianlei, Wu, Hao, Li, Cui, Qin, Cheng-Feng, Wen, Zhexing, Wu, Qing-Feng, Tang, Hengli, Xu, Zhiheng, Jin, Peng, Song, Hongjun, Ming, Guo-Li, Lee, Gabsang
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Abstract/Description: Zika virus (ZIKV) infection is associated with neurological disorders of both the CNS and peripheral nervous systems (PNS), yet few studies have directly examined PNS infection. Here we show that intraperitoneally or intraventricularly injected ZIKV in the mouse can infect and impact peripheral neurons in vivo. Moreover, ZIKV productively infects stem-cell-derived human neural crest cells and peripheral neurons in vitro, leading to increased cell death, transcriptional dysregulation and cell...
Show moreZika virus (ZIKV) infection is associated with neurological disorders of both the CNS and peripheral nervous systems (PNS), yet few studies have directly examined PNS infection. Here we show that intraperitoneally or intraventricularly injected ZIKV in the mouse can infect and impact peripheral neurons in vivo. Moreover, ZIKV productively infects stem-cell-derived human neural crest cells and peripheral neurons in vitro, leading to increased cell death, transcriptional dysregulation and cell-type-specific molecular pathology.
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Date Issued: 2017-09-01
Identifier: FSU_pmch_28758997, 10.1038/nn.4612, PMC5575960, 28758997, 28758997, nn.4612
Format: Citation

Title: Zika virus and neural developmental defects: building a case for a cause.
Creator: Ogden, Sarah C., Hammack, Christy, Tang, Hengli
Date Issued: 2016-05
Identifier: FSU_libsubv1_wos_000375885300013, 10.1007/s11427-016-5053-2
Format: Citation

Title: Zero Harm During Transitions in Care- Post Implementation Evaluation.
Creator: Drinkwater, Bliss Hahn
Abstract/Description: The purpose of this project is to evaluate the effectiveness of and adherence to the Zero Harm During Transitions in Care process for a full year post implementation.
Date Issued: 2020-04-23
Identifier: FSU_libsubv1_scholarship_submission_1587689347_f73759bf
Format: Citation

Title: Zerbe: The Growth of a Picture.
Creator: Strozier, Robert Manning
Date Issued: 1958-02-21
Identifier: FSU_HPUA_2001012_B1800_F07_13
Format: Document (PDF)

Title: Youthful recreations.
Creator: Johnson, Jacob
Date Issued: 1802
Identifier: 21718256, FSU_GV1203Y681802, fsu:642421
Format: E-book

Title: Youth's murder for interracial flirting galvinzed civil rights drive.
Creator: Chicago Daily Law Bulletin, Tobias, Joseph, Sewell, Dan
Date Issued: 1995-08-29
Identifier: FSU_MSS2017_002_MC5_F05_08
Format: Document (PDF)

Title: Youth Participation in Qualitative Research: Challenges and Possibilities.
Creator: Schelbe, Lisa, Chanmugam, Amy, Moses, Tally, Saltzburg, Susan, Williams, Lela Rankin, Letendre, Joan
Abstract/Description: Research often excludes youth participants, omitting their social and psychological realities, undermining their rights to participate and benefit from research, and weakening the validity of research. Researchers may be discouraged from including youth due to logistical (e.g. gaining access) or ethical (e.g. coercion risks based on developmental level) concerns. Increased discussion is needed around appropriate methods to use with child and youth participants that manage challenges related...
Show moreResearch often excludes youth participants, omitting their social and psychological realities, undermining their rights to participate and benefit from research, and weakening the validity of research. Researchers may be discouraged from including youth due to logistical (e.g. gaining access) or ethical (e.g. coercion risks based on developmental level) concerns. Increased discussion is needed around appropriate methods to use with child and youth participants that manage challenges related to developmental capacities, legal status, power differentials, and unpredictable aspects of qualitative research. This paper pools experiences of six researchers, describing solutions we have developed in studies employing varied qualitative methodologies with varied vulnerable youth sub-populations. We detail successful approaches to access, compensation, consent, assent, and confidentiality. Social work researchers are well suited to navigate the challenges, and we share our examples with the aim of facilitating increased youth participation in research.
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Date Issued: 2014-11-10
Identifier: FSU_libsubv1_scholarship_submission_1505837771_741d9110, 10.1177/1473325014556792
Format: Citation

Title: Youth Lagoon.
Identifier: FSUHPUA_2014028_047
Format: Image (JPEG2000)

Title: Youth Lagoon.
Identifier: FSUHPUA_2014028_046
Format: Image (JPEG2000)

Title: Youth in our time: a study of juvenile deliquency trends in the United States and in Gainesville and Alachua county, Florida, 1939-1945.
Creator: Bell, Betty
Date Issued: 1946
Identifier: 159052, FSDT159052, fsu:18245
Format: Document (PDF)

Title: Youth Development and Reentry.
Creator: Mears, Daniel P., Travis, Jeremy
Date Issued: 2004-01-01
Identifier: FSU_libsubv1_scholarship_submission_1548280672_48ff5bf0, 10.1177/1541204003260044
Format: Citation

Title: Your Diligent Looking Discover the Lacking: Individual and Societal Reconciliation in Isherwood and Auden's 1930S Literature.
Creator: Lonsberry, Samuel, Department of English
Abstract/Description: The work aims to explore the similarities and differences between Christopher Isherwood and W.H. Auden's 1930s literature. As unique authors within the decade, emphasizing artifice and aesthetics in relation to socially-conscious writing, both artists provide an interesting study of one sub-category of 1930s literature. Defining themselves against the likes of George Orwell and Aldous Huxley, Auden and Isherwood attempt to retain the aesthetic-driven forms of 1920s Modernism while further...
Show moreThe work aims to explore the similarities and differences between Christopher Isherwood and W.H. Auden's 1930s literature. As unique authors within the decade, emphasizing artifice and aesthetics in relation to socially-conscious writing, both artists provide an interesting study of one sub-category of 1930s literature. Defining themselves against the likes of George Orwell and Aldous Huxley, Auden and Isherwood attempt to retain the aesthetic-driven forms of 1920s Modernism while further melding them with more politically focused cultural trends.
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Date Issued: 2015
Identifier: FSU_migr_uhm-0506
Format: Thesis

Title: Your Bible River Tour.
Creator: First Baptist Church of Tallahassee
Date Issued: 2006-02-26
Identifier: FSU_FBCTLH_02262006a
Format: Document (PDF)

Title: The young reviewers, or, The poems dissected.
Creator: Copley, Esther, Darton, William
Date Issued: 1821
Identifier: 33213569, FSU_PR4503C63Y681821, fsu:646494
Format: E-book

Title: Young peoples history of the world: for one hundred years.
Date Issued: 18??
Identifier: 433010736, 197455, FSDT197455, fsu:82291
Format: E-book

Title: The young master of Hyson Hall.
Creator: Stockton, Frank Richard, Davisson, Virginia H., Stephens, Charles H.
Date Issued: 1899
Identifier: 431959573, 217113, FSDT217113, fsu:103105
Format: E-book

Title: The young gentleman and lady's instructor, or, New reader and speaker: being a choice collection of pieces of poetry and prose : designed as a pleasing and useful companion to young persons in general.
Date Issued: 1808
Identifier: 33128720, FSU_PE1120Y681808, fsu:632223
Format: E-book

Title: Young England's little library: a collection of original tales for children, in prose and verse.
Creator: Vizetelly Brothers & Co, Orr & Compy
Date Issued: 1844
Identifier: 24880975, FSU_PZ6Y681844, fsu:629450
Format: E-book

Title: The young Crusoe.
Date Issued: 1864
Identifier: FSUGold_001, fsu:93819
Format: E-book

Title: Young Christians̕ companion: being a selection of hymns, particularly adapted to private devotion and conference meetings.
Creator: Davis, Gustavus F.
Date Issued: 1826
Identifier: 21212902, FSU_BV380D291826, fsu:169665
Format: E-book

Title: The Young And Bright Type Ia Supernova Asassn-141p: Discovery, Early-time Observations, First-light Time, Distance To Ngc 4666, And Progenitor Constraints.
Creator: Shappee, B. J., Piro, A. L., Holoien, T. W.-S., Prieto, J. L., Contreras, C., Itagaki, K., Burns, C. R., Kochanek, C. S., Stanek, K. Z., Alper, E., Basu, U., Beacom, J. F.,...
Show moreShappee, B. J., Piro, A. L., Holoien, T. W.-S., Prieto, J. L., Contreras, C., Itagaki, K., Burns, C. R., Kochanek, C. S., Stanek, K. Z., Alper, E., Basu, U., Beacom, J. F., Bersier, D., Brimacombe, J., Conseil, E., Danilet, A. B., Dong, Subo, Falco, E., Grupe, D., Hsiao, E. Y., Kiyota, S., Morrell, N., Nicolas, J., Phillips, M. M., Pojmanski, G., Simonian, G., Stritzinger, M., Szczygiel, D. M., Taddia, F., Thompson, T. A., Thorstensen, J., Wagner, M. R., Wozniak, P. R.
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Abstract/Description: On 2014 December 9.61, the All-sky Automated Survey for SuperNovae (ASAS-SN or "Assassin") discovered ASASSN-141p just similar to 2 days after first light using a global array of 14 cm diameter telescopes. ASASSN-141p went on to become a bright supernova (V = 11.94 mag), second only to SN 2014J for the year. We present prediscovery photometry (with a detection less than a day after first light) and ultraviolet through near-infrared photometric and spectroscopic data covering the rise and fall...
Show moreOn 2014 December 9.61, the All-sky Automated Survey for SuperNovae (ASAS-SN or "Assassin") discovered ASASSN-141p just similar to 2 days after first light using a global array of 14 cm diameter telescopes. ASASSN-141p went on to become a bright supernova (V = 11.94 mag), second only to SN 2014J for the year. We present prediscovery photometry (with a detection less than a day after first light) and ultraviolet through near-infrared photometric and spectroscopic data covering the rise and fall of ASASSN-141p for more than 100 days. We find that ASASSN-141p had a broad light curve (Delta m(15) (B) = 0.80 +/- 0.05), a B-band maximum at 2457015.82 +/- 0.03, a rise time of 16.941(-0.10)(+0.11) days, and moderate host-galaxy extinction (E (B - V)host = 0.33 +/- 0.06). Using ASASSN-141p, we derive a distance modulus for NGC 4666 of mu = 30.8 +/- 0.2, corresponding to a distance of 14.7 +/- 1.5 Mpc. However, adding ASASSN-141p to the calibrating sample of Type Ia supernovae still requires an independent distance to the host galaxy. Finally, using our early-time photometric and spectroscopic observations, we rule out red giant secondaries and, assuming a favorable viewing angle and explosion time, any nondegenerate companion larger than 0.34 RG(circle dot).
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Date Issued: 2016-08-01
Identifier: FSU_libsubv1_wos_000381977900044, 10.3847/0004-637x/826/2/144
Format: Citation

Title: Young Adult Outcomes and the Life-Course Penalties of Parental Incarceration.
Creator: Mears, Daniel P., Siennick, Sonja E.
Abstract/Description: Objectives: The transition to adulthood can be challenging, especially for children of incarcerated parents. Drawing on reentry and life-course scholarship, we argue that parental incarceration may adversely affect multiple life outcomes for children as they progress from adolescence into adulthood and that such effects may persist from early young adulthood into late young adulthood. Methods: The study uses propensity score matching analyses of National Longitudinal Study of Adolescent...
Show moreObjectives: The transition to adulthood can be challenging, especially for children of incarcerated parents. Drawing on reentry and life-course scholarship, we argue that parental incarceration may adversely affect multiple life outcomes for children as they progress from adolescence into adulthood and that such effects may persist from early young adulthood into late young adulthood. Methods: The study uses propensity score matching analyses of National Longitudinal Study of Adolescent Health data (N = 12,844). Results: Analyses identified harmful effects of parental incarceration on many life domains, including criminal behavior, mental health, illegal drug use, education, earnings, and intimate relationships. These effects typically surfaced by early young adulthood and continued into late young adulthood. Conclusions: The results suggest that parental incarceration constitutes a significant turning point in the lives of young people and underscore the importance of life-course perspectives for understanding incarceration effects. They also illustrate that formal punishment policies may create harms that potentially offset intended benefit
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Date Issued: 2016-02-01
Identifier: FSU_libsubv1_scholarship_submission_1459443417, 10.1177/0022427815592452
Format: Citation

Title: You've Earned It! Searching for a Defensible Basis for Desert in Wages.
Creator: Jenkins, Ryan
Abstract/Description: In my thesis, I propose a new theory of wages as deserved income. I take a look at two prominent philosophers’ discussions on the subject, and find they are both lacking. George Sher believes that desert in wages can best be explained by appealing to the violation of moral standards that dictate how we believe the world should be. He says that, because subordinating our labor to another’s ends (i.e. ‘working’) violates some “independent standard,” wages are deserved to offset this loss of...
Show moreIn my thesis, I propose a new theory of wages as deserved income. I take a look at two prominent philosophers’ discussions on the subject, and find they are both lacking. George Sher believes that desert in wages can best be explained by appealing to the violation of moral standards that dictate how we believe the world should be. He says that, because subordinating our labor to another’s ends (i.e. ‘working’) violates some “independent standard,” wages are deserved to offset this loss of autonomy. A wage is “uniquely suited” to allow a worker to pursue his own goals in turn, says Sher. Joel Feinberg argues that, as far as wages are deserved at all, they are deserved only as compensation for especially difficult, dangerous or unpleasant work, and that they can only explain deserved differentials in pay. He rejects the idea that deserved wages can be explained as a reward. My own theory, briefly, is this: wages are deserved as a reward after a worker has (1) put forth an effort that (2) has been directed toward the end of another and (3) is socially valuable. Finally, I survey the literature in the living wage movement. Finding it lacking in the language of desert, I propose that the proponents of a living wage adopt an argument like mine. That is, I suggest they give to desert a more central role in their discussions about why workers should receive a living wage.
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Date Issued: 2008-11-12
Identifier: 210372, FSDT210372, fsu:19178
Format: Document (PDF)

Title: You Shouldn't.
Creator: Wendi Adelson
Identifier: FSU_9432595714_79724
Format: Document (PDF)

Title: You Need Not Be a Star to Have a Stand-In.
Creator: First Baptist Church of Tallahassee
Date Issued: 1997-03-02
Identifier: FSU_FBCTLH_03021997
Format: Document (PDF)

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