You are here

Laminar Organization of Encoding and Memory Reactivation in the Parietal Cortex.

Title: Laminar Organization of Encoding and Memory Reactivation in the Parietal Cortex.
1 views
0 downloads
Name(s): Wilber, Aaron A, author
Skelin, Ivan, author
Wu, Wei, author
McNaughton, Bruce L, author
Type of Resource: text
Genre: Journal Article
Text
Date Issued: 2017-09-13
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Egocentric neural coding has been observed in parietal cortex (PC), but its topographical and laminar organization is not well characterized. We used multi-site recording to look for evidence of local clustering and laminar consistency of linear and angular velocity encoding in multi-neuronal spiking activity (MUA) and in the high-frequency (300-900 Hz) component of the local field potential (HF-LFP), believed to reflect local spiking activity. Rats were trained to run many trials on a large circular platform, either to LED-cued goal locations or as a spatial sequence from memory. Tuning to specific self-motion states was observed and exhibited distinct cortical depth-invariant coding properties. These patterns of collective local and laminar activation during behavior were reactivated in compressed form during post-experience sleep and temporally coupled to cortical delta waves and hippocampal sharp-wave ripples. Thus, PC neuron motion encoding is consistent across cortical laminae, and this consistency is maintained during memory reactivation.
Identifier: FSU_pmch_28910623 (IID), 10.1016/j.neuron.2017.08.033 (DOI), PMC5679317 (PMCID), 28910623 (RID), 28910623 (EID), S0896-6273(17)30748-1 (PII)
Keywords: Delta wave, High-frequency local field potential, Hippocampus, Memory reactivation, Modular organization, Movement decoding, Multi-unit activity, Parietal cortex, Posterior parietal cortex, Template matching
Grant Number: F32 MH099682, K99 AG049090, R00 AG049090
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679317.
Subject(s): Animals
Hippocampus/physiology
Locomotion/physiology
Male
Memory/physiology
Neurons/physiology
Parietal Lobe/cytology
Parietal Lobe/physiology
Rats
Self Stimulation
Sleep/physiology
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_pmch_28910623
Host Institution: FSU
Is Part Of: Neuron.
1097-4199
Issue: iss. 6, vol. 95

Choose the citation style.
Wilber, A. A., Skelin, I., Wu, W., & McNaughton, B. L. (2017). Laminar Organization of Encoding and Memory Reactivation in the Parietal Cortex. Neuron. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_28910623