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10-desacetoxytaxol derivatives

Title: 10-desacetoxytaxol derivatives.
Name(s): Farina, Vittorio, inventor
Holton, Robert A., inventor
Chen, Shu-Hui, inventor
Type of Resource: text
Genre: Utility
Date Created: 1992-09-22
Date Issued: 1994-09-27
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: The present invention relates to 10-desacetoxytaxol and derivatives thereof, which are useful as antitumor agents. These compounds have the formula ##STR1## wherein R.sub.2 is hydrogen, hydroxy or a protected hydroxy group; R.sub.3 and R.sub.4 are independently hydrogen, hydroxy, a protected hydroxy group, methyl, --SH, --NH.sub.2, or --NR.sub.8 R.sub.9 ; R.sub.5 is R.sub.10, or --OR.sub.10 ; R.sub.6 and R.sub.7 are independently hydrogen, alkyl, or aryl; R.sub.8 and R.sub.9 are independently hydrogen, alkyl, alkenyl, alkynyl, or aryl; and R.sub.10 is alkoxy, alkyl, alkenyl, alkynl, or aryl.
Identifier: FSU_uspto_5350866 (IID), 5350866 (patent number), 691280 (inventor key), 07/949449 (app id), 600b83161da1122888348587dc18798c (assignee id)
Cited by US patents: 73
Persistent Link to This Record:
Use and Reproduction: Copyright not evaluated
Host Institution: FSU

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10-desacetoxytaxol derivatives. (1994). 10-desacetoxytaxol derivatives. Retrieved from