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Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them

Title: Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them.
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Name(s): Holton, Robert A., inventor
Nadizadeh, Hossain, inventor
Rengan, Kasthuri, inventor
Type of Resource: text
Genre: Utility
Text
Date Created: 1992-11-13
Date Issued: 1994-02-01
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Taxane derivatives of the formula ##STR1## wherein R.sub.1 is phenyl or p-nitrophenyl, PA1 R.sub.3 is furyl or thienyl, PA1 T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2, PA1 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl or monocylic aryl, PA1 Ac is acetyl, and PA1 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Identifier: FSU_uspto_5283253 (IID), 5283253 (patent number), 711524 (inventor key), 07/975723 (app id), 600b83161da1122888348587dc18798c (assignee id)
Cited by US patents: 99
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_uspto_5283253
Use and Reproduction: Copyright not evaluated
Owner Institution: FSU

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Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them. (1994). Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5283253