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Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them

Title: Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them.
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Name(s): Holton, Robert A., inventor
Nadizadeh, Hossain, inventor
Beidiger, Ronald J., inventor
Type of Resource: text
Genre: Utility
Text
Date Created: 1992-04-03
Date Issued: 1993-07-13
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: A taxane derivative of the formula ##STR1## wherein ##STR2## Z is --OT.sub.1, T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2, PA0 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl, C.sub.1 -C.sub.6 alkynyl or monocylic aryl, PA0 R.sub.3 is benzoyl, substituted benzoyl or C.sub.1 -C.sub.6 alkoxycarbonyl, PA0 Ac is acetyl, and PA0 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Identifier: FSU_uspto_5227400 (IID), 5227400 (patent number), 711524 (inventor key), 07/862819 (app id), 600b83161da1122888348587dc18798c (assignee id)
Cited by US patents: 110
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_uspto_5227400
Use and Reproduction: Copyright not evaluated
Owner Institution: FSU

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Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. (1993). Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5227400