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Method for preparation of taxol using .beta.-lactam

Title: Method for preparation of taxol using .beta.-lactam.
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Name(s): Holton, Robert A., inventor
Type of Resource: text
Genre: Utility
Text
Date Created: 1989-09-29
Date Issued: 1992-12-29
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: A .beta.-lactam of the formula: ##STR1## wherein R.sub.1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R.sub.2 is hydrogen, alkyl, acyl, acetal, ethoxyethyl, or other hydroxyl protecting group; and R.sub.3 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; and process for the preparation of taxol comprising contacting said .beta.-lactam and an alcohol in the presence of an activating agent to provide a taxol intermediate, and converting the intermediate to taxol.
Identifier: FSU_uspto_5175315 (IID), 5175315 (patent number), 711524 (inventor key), 07/415028 (app id), 600b83161da1122888348587dc18798c (assignee id)
Cited by US patents: 145
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_uspto_5175315
Use and Reproduction: Copyright not evaluated
Owner Institution: FSU

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Method for preparation of taxol using .beta.-lactam. (1992). Method for preparation of taxol using .beta.-lactam. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5175315