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effects of L. reuteri on anxiety-like and social affiliation behaviors in female prairie voles

Title: The effects of L. reuteri on anxiety-like and social affiliation behaviors in female prairie voles.
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Name(s): McGuire, George Patrick, author
Type of Resource: text
Genre: Text
Bachelor Thesis
Date Issued: 2017-12-08
Physical Form: computer
Physical Form: online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Microbial species living in our gastrointestinal tract, commonly called microbiota, communicate with the Central Nervous System (CNS) via the vagus nerve and production of metabolites, creating a gut-brain-axis. Via this connection, the microbiota has been shown to affect behavior, particularly anxiety-like and social behaviors. This study was designed to evaluate the effects of Lactobacillus reuteri treatment on anxiety-like and social affiliation behaviors in the prairie vole (Microtus ochrogaster) model. Sexually naïve female prairie voles received live L. reuteri treatment or heat-killed L. reuteri over a 28-day period. Then subjects’ behavior was evaluated during tests for anxiety-like behavior (Open Field and Elevated Plus Maze) and tests for social affiliation behavior (Social Affiliation Test). Live L. reuteri treatment resulted in decreased time spent in the conspecific chamber, decreased time spent interacting with the conspecific, and increased time in the corner of the conspecific chamber, indicating decreased social affiliation behavior. These data demonstrate behavior-specific effects of L. reuteri, suggesting a role in social behavior of prairie voles.
Identifier: FSU_libsubv1_scholarship_submission_1512752696_396faa95 (IID)
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_libsubv1_scholarship_submission_1512752696_396faa95
Owner Institution: FSU

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McGuire, G. P. (2017). The effects of L. reuteri on anxiety-like and social affiliation behaviors in female prairie voles. Retrieved from http://purl.flvc.org/fsu/fd/FSU_libsubv1_scholarship_submission_1512752696_396faa95