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Macrophage cell death upon intracellular bacterial infection.

Title: Macrophage cell death upon intracellular bacterial infection.
Name(s): Lai, Xin-He, author
Xu, Yunsheng, author
Chen, Xiao-Ming, author
Ren, Yi, author
Type of Resource: text
Genre: Journal Article
Date Issued: 2015-04-26
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Macrophage-pathogen interaction is a complex process and the outcome of this tag-of-war for both sides is to live or die. Without attempting to be comprehensive, this review will discuss the complexity and significance of the interaction outcomes between macrophages and some facultative intracellular bacterial pathogens as exemplified by Francisella, Salmonella, Shigella and Yersinia. Upon bacterial infection, macrophages can die by a variety of ways, such as apoptosis, autophagic cell death, necrosis, necroptosis, oncosis, pyronecrosis, pyroptosis etc, which is the focus of this review.
Identifier: FSU_pmch_26690967 (IID), 10.14800/Macrophage.779 (DOI), PMC4683602 (PMCID), 26690967 (RID), 26690967 (EID)
Keywords: Apoptosis, Autophagic cell death, Bacterial pathogen, Macrophage polarization, Necroptosis, Necrosis, Oncosis, Pyronecrosis, Pyroptosis
Grant Number: R01 GM100474
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at
Persistent Link to This Record:
Owner Institution: FSU
Is Part Of: Macrophage.
Issue: vol. 2

Choose the citation style.
Lai, X. -H., Xu, Y., Chen, X. -M., & Ren, Y. (2015). Macrophage cell death upon intracellular bacterial infection. Macrophage. Retrieved from