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14-3-3 proteins in neurological disorders.

Title: 14-3-3 proteins in neurological disorders.
Name(s): Foote, Molly, author
Zhou, Yi, author
Type of Resource: text
Genre: Journal Article
Date Issued: 2012-01-01
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: 14-3-3 proteins were originally discovered as a family of proteins that are highly expressed in the brain. Through interactions with a multitude of binding partners, 14-3-3 proteins impact many aspects of brain function including neural signaling, neuronal development and neuroprotection. Although much remains to be learned and understood, 14-3-3 proteins have been implicated in a variety of neurological disorders based on evidence from both clinical and laboratory studies. Here we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins in both neurodegenerative and neuropsychiatric diseases.
Identifier: FSU_pmch_22773956 (IID), PMC3388734 (PMCID), 22773956 (RID), 22773956 (EID)
Keywords: 14-3-3, Neurodegenerative diseases, Neurodevelopment, Neuropsychiatric diseases
Grant Number: R01 NS050355
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at
Persistent Link to This Record:
Host Institution: FSU
Is Part Of: International journal of biochemistry and molecular biology.
Issue: iss. 2, vol. 3

Choose the citation style.
Foote, M., & Zhou, Y. (2012). 14-3-3 proteins in neurological disorders. International Journal Of Biochemistry And Molecular Biology. Retrieved from