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Comparison of oxygenation in peripheral muscle during submaximal aerobic exercise, in persons with COPD and healthy, matched-control persons.

Title: Comparison of oxygenation in peripheral muscle during submaximal aerobic exercise, in persons with COPD and healthy, matched-control persons.
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Name(s): Austin, Krista G, author
Mengelkoch, Larry, author
Hansen, Jennifer, author
Shahady, Edward, author
Sirithienthad, Prawee, author
Panton, Lynn, author
Type of Resource: text
Genre: Journal Article
Text
Date Issued: 2006-01-01
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: The purpose of this study was to compare peripheral muscle oxygenation in persons with chronic obstructive pulmonary disease (COPD) to healthy control persons, during submaximal exercise. Eight persons with COPD (forced expiratory volume in one second [FEV1] = 1.00 +/- 0.27 L) and eight healthy control persons (FEV, = 1.88 +/- 0.55L) performed a submaximal graded exercise test (GXT), and completed 4 min of constant load exercise (CON) at 50% of peak GXT. Measurements included oxygen uptake, heart rate, arterial oxygen saturation and peripheral muscle oxygenation (%StO2) at rest, during exercise, and recovery. Significantly greater workloads were attained for controls compared with COPD for peak GXT and CON. No significant differences in %StO2 were observed between groups at: rest (GXT: 29.5 +/- 22.8 vs 30.4 +/- 17.3%; CON: 33.3 +/- 15.4 vs 35.1 +/- 17.2%); peak GXT (29.4 +/- 19.4 vs 26.5 +/- 15.9%); 4 min of CON (25.9 +/- 13.5 vs 34.5 +/- 21.8%); and recovery (GXT: 46.6 +/- 29.1 vs 44.3 +/- 21.7%; CON: 40.9 +/- 21.5 vs 44.5 +/- 23.2%). These results suggest that peripheral skeletal muscle oxygenation is not compromised in COPD during submaximal exercise, and limitations in exercise capacity are most likely a result of muscle disuse and poor lung function.
Identifier: FSU_pmch_18044103 (IID), PMC2707799 (PMCID), 18044103 (RID), 18044103 (EID)
Publication Note: This NIH-funded author manuscript originally appeared in PubMed Central at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707799.
Subject(s): Aged
Aged, 80 and over
Case-Control Studies
Exercise/physiology
Exercise Test
Female
Forced Expiratory Volume
Humans
Male
Middle Aged
Muscle, Skeletal/chemistry
Muscle, Skeletal/metabolism
Oxygen/analysis
Oxygen Consumption
Pulmonary Disease, Chronic Obstructive/metabolism
Spectroscopy, Near-Infrared
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_pmch_18044103
Owner Institution: FSU
Is Part Of: International journal of chronic obstructive pulmonary disease.
1176-9106
Issue: iss. 4, vol. 1

Choose the citation style.
Austin, K. G., Mengelkoch, L., Hansen, J., Shahady, E., Sirithienthad, P., & Panton, L. (2006). Comparison of oxygenation in peripheral muscle during submaximal aerobic exercise, in persons with COPD and healthy, matched-control persons. International Journal Of Chronic Obstructive Pulmonary Disease. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_18044103