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Surface Charge Density in Polyelectrolyte Multilayers and Its Role in Cell Behavior

Title: Surface Charge Density in Polyelectrolyte Multilayers and Its Role in Cell Behavior.
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Name(s): Arias Ramos, Carlos J, author
Schlenoff, Joseph B., professor directing dissertation
Keller, Thomas C. S., university representative
Marshall, Alan G. (Alan George), committee member
Mattoussi, Hedi, committee member
Florida State University, degree granting institution
College of Arts and Sciences, degree granting college
Department of Chemistry and Biochemistry, degree granting department
Type of Resource: text
Genre: Text
Issuance: monographic
Date Issued: 2016
Publisher: Florida State University
Place of Publication: Tallahassee, Florida
Physical Form: computer
online resource
Extent: 1 online resource (142 pages)
Language(s): English
Abstract/Description: The role of charge density in polyelectrolyte multilayer coatings used in 2-D cell culture was investigated in this dissertation. First it is important to comprehend that cells do not attach directly to surfaces, they attach to proteins adhered to surfaces. Surface charge density in polyelectrolyte films affects not only protein coverage, but also interferes with protein exchange (Vroman effect), highly charge surfaces favor irreversible absorption of non-adhesive proteins like albumin, which directly affects cell behavior on these ultrathin films.
Identifier: FSU_2016SP_AriasRamos_fsu_0071E_13111 (IID)
Submitted Note: A Dissertation submitted to the Department of Chemistry and Biochemistry in partial fulfillment of the Doctor of Philosophy.
Degree Awarded: Spring Semester 2016.
Date of Defense: April 4, 2016.
Bibliography Note: Includes bibliographical references.
Advisory Committee: Joseph B. Schlenoff, Professor Directing Dissertation; Thomas C. S. Keller, University Representative; Alan Marshall, Committee Member; Hedi Mattoussi, Committee Member.
Subject(s): Chemistry
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_2016SP_AriasRamos_fsu_0071E_13111
Owner Institution: FSU

Choose the citation style.
Arias Ramos, C. J. (2016). Surface Charge Density in Polyelectrolyte Multilayers and Its Role in Cell Behavior. Retrieved from http://purl.flvc.org/fsu/fd/FSU_2016SP_AriasRamos_fsu_0071E_13111