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Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival

Title: Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival.
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Inaccessible indefinitely due to copyright restrictions.

Name(s): Hagler, Shaye, author
Department of Chemistry and Biochemistry
Type of Resource: text
Genre: Text
Issuance: serial
Date Issued: 2013
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Mesenchymal stem cells (MSC) have a wide variety of promising clinical applications including the treatment of brain disorders and injury, cardiovascular disease, and cancer. To fully exploit their potential, we need a better understanding of the cellular and molecular mechanisms that govern stem cell division and survival. We have hypothesized that the essential trace element zinc regulates the proliferation and survival of rat and human bone marrow-derived MSC. Proliferation of MSC is impaired by zinc deficiency. For example, after 48h of zinc deficiency, proliferation was reduced by 50% (p
Identifier: FSU_migr_uhm-0181 (IID)
Keywords: zinc deficiency, mesenchymal stem cells, zinc
Submitted Note: A Thesis submitted to the Department of Chemistry & Biochemistry in partial fulfillment of the requirements for graduation with Honors in the Major.
Degree Awarded: Spring Semester, 2013.
Date of Defense: April 17, 2013.
Subject(s): Biochemistry
Cytology
Nutrition
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_migr_uhm-0181
Owner Institution: FSU
Is Part of Series: Honors Theses.

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Hagler, S. (2013). Zinc Regulation of Mesenchymal Stem Cell Proliferation and Survival. Retrieved from http://purl.flvc.org/fsu/fd/FSU_migr_uhm-0181