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Cholesterol, Triglycerides, and the Five-Factor Model of Personality

Title: Cholesterol, Triglycerides, and the Five-Factor Model of Personality.
Name(s): Sutin, Angelina, author
Terracciano, Antonio, author
Deiana, Barbara, author
Uda, Manuela, author
Schlessinger, David, author
Lakatta, Edward, author
Costa, Paul, author
Type of Resource: text
Genre: Text
Issuance: serial
Date Issued: 2010
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Unhealthy lipid levels are among the leading controllable risk factors for coronary heart disease. To identify the psychological factors associated with dyslipidemia, this study investigates the personality correlates of cholesterol (total, LDL, and HDL) and triglycerides. A community-based sample (N=5532) from Sardinia, Italy, had their cholesterol and triglyceride levels assessed and completed a comprehensive personality questionnaire, the NEO-PI-R. All analyses controlled for age, sex, BMI, smoking, drinking, hypertension, and diabetes. Low Conscientiousness and traits related to impulsivity were associated with lower HDL cholesterol and higher triglycerides. Compared to the lowest 10%, those who scored in top 10% on Impulsivity had a 2.5 times greater risk of exceeding the clinical threshold for elevated triglycerides (OR=2.51, CI=1.56-4.07). In addition, sex moderated the association between trait depression (a component of Neuroticism) and HDL cholesterol, such that trait depression was associated with lower levels of HDL cholesterol in women but not men. When considering the connection between personality and health, unhealthy lipid profiles may be one intermediate biomarker between personality and morbidity and mortality.
Identifier: FSU_migr_mhs-0028 (IID), 10.1016/j.biopsycho.2010.01.012 (DOI)
Keywords: personality, depression, impulsivity, cholesterol, triglycerides
Uncontrolled subjects: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Blood Chemical Analysis, Cholesterol, Female, Humans, Italy, Logistic Models, Male, Middle Aged, Personality, Personality Inventory, Residence Characteristics, Sex Factors, Triglycerides, Young Adult
Note: Published in final edited form as: Biol Psychol. 2010 May ; 84(2): 186–191. doi:10.1016/j.biopsycho.2010.01.012
Citation: Sutin AR, Terracciano A, Deiana B, Uda M, Schlessinger D, Lakatta EG, Costa PT Jr. (2010). Cholesterol, triglycerides, and the Five-Factor Model of personality. Biol Psychol, 84(2):186-91.
Subject(s): Diagnosis, Laboratory -- Equipment and supplies
Human behavior
Medical sciences
Mental illness
Social aspects
Polycyclic compounds
Persistent Link to This Record:
Host Institution: FSU
Is Part of Series: Behavioral Sciences and Social Medicine Faculty Publications.
Is Part Of: Biological Psychology.
Issue: 2, 84

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Sutin, A., Terracciano, A., Deiana, B., Uda, M., Schlessinger, D., Lakatta, E., & Costa, P. (2010). Cholesterol, Triglycerides, and the Five-Factor Model of Personality. Biological Psychology. Retrieved from