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Comparative Effects of Dried Plum and Dried Apple On Bone In Postmenopausal Women

Title: Comparative Effects of Dried Plum and Dried Apple On Bone In Postmenopausal Women.
Name(s): Hooshmand, Shirin, author
Chai, Sheau Ching, author
Saadat, Raz, author
Payton, Mark, author
Brummel-Smith, Kenneth, author
Arjmandi, Bahram, author
Type of Resource: text
Genre: Text
Issuance: serial
Date Issued: 2011
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Aside from existing drug therapies, certain lifestyle and nutritional factors are known to reduce the risk of osteoporosis. Among the nutritional factors, dried plum or prunes (Prunus domestica L.) is the most effective fruit in both preventing and reversing bone loss. The objective of the present study was to examine the extent to which dried plum reverses bone loss in osteopenic postmenopausal women. We recruited 236 women, 1-10 years postmenopausal, not on hormone replacement therapy or any other prescribed medication known to influence bone metabolism. Qualified participants (n 160) were randomly assigned to one of the two treatment groups: dried plum (100 g/d) or dried apple (comparative control). Participants received 500 mg Ca plus 400 IU (10 μg) vitamin D daily. Bone mineral density (BMD) of lumbar spine, forearm, hip and whole body was assessed at baseline and at the end of the study using dual-energy X-ray absorptiometry. Blood samples were collected at baseline, 3, 6 and 12 months to assess bone biomarkers. Physical activity recall and 1-week FFQ were obtained at baseline, 3, 6 and 12 months to examine physical activity and dietary confounders as potential covariates. Dried plum significantly increased BMD of ulna and spine in comparison with dried apple. In comparison with corresponding baseline values, only dried plum significantly decreased serum levels of bone turnover markers including bone-specific alkaline phosphatase and tartrate-resistant acid phosphatase-5b. The findings of the present study confirmed the ability of dried plum in improving BMD in postmenopausal women in part due to suppressing the rate of bone turnover.
Identifier: FSU_migr_geriatrics_faculty_publications-0043 (IID), 10.1017/S000711451100119X (DOI)
Keywords: Bone Density, Bone Diseases, Osteoporosis, Postmenopausal
Uncontrolled subjects: Acid Phosphatase, Aged, Alkaline Phosphatase, Anthropometry, Biological Markers, Bone Density, Bone Diseases, Metabolic, Bone and Bones, Calcium, Diet, Exercise, Female, Humans, Isoenzymes, Malus, Middle Aged, Osteoporosis, Postmenopausal, Postmenopause, Prunus, Spine, Ulna
Note: Published in final edited form as" title="The British journal of nutrition.">Br J Nutr. 2011 Sep;106(6):923-30.: Published online May 31, 2011. doi: 10.1017/S000711451100119X
Citation: Hooshmand S, Chai SC, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH. Comparative effects of dried plum and dried apple on bone in postmenopausal women, British Journal of Nutrition, Br J Nutr. 2011; 106: 923-30.
Subject(s): Geriatrics
Medical sciences
Persistent Link to This Record:
Owner Institution: FSU
Is Part of Series: Department of Geriatrics Faculty Publications.
Is Part Of: The British Journal of Nutrition.
Issue: 6, 106

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Hooshmand, S., Chai, S. C., Saadat, R., Payton, M., Brummel-Smith, K., & Arjmandi, B. (2011). Comparative Effects of Dried Plum and Dried Apple On Bone In Postmenopausal Women. British Journal Of Nutrition. Retrieved from