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Zn(II)-coordination modulated ligand photophysical processes – the development of fluorescent indicators for imaging biological Zn(II) ions

Title: Zn(II)-coordination modulated ligand photophysical processes – the development of fluorescent indicators for imaging biological Zn(II) ions.
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Name(s): Zhu, Lei, 1978-, author
Yuan, Zhao, author
Simmons, J., author
Sreenath, Kesavapillai, author
Type of Resource: text
Genre: Text
Issuance: serial
Date Issued: 2014
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: Molecular photophysics and metal coordination chemistry are the two fundamental pillars that support the development of fluorescent cation indicators. In this article, we describe how Zn(II)-coordination alters various ligand-centered photophysical processes that are pertinent to developing Zn(II) indicators. The main aim is to show how small organic Zn(II) indicators work under the constraints of specific requirements, including Zn(II) detection range, photophysical requirements such as excitation energy and emission color, temporal and spatial resolutions in a heterogeneous intracellular environment, and fluorescence response selectivity between similar cations such as Zn(II) and Cd(II). In the last section, the biological questions that fluorescent Zn(II) indicators help to answer are described, which have been motivating and challenging this field of research.
Identifier: FSU_migr_chm_faculty_publications-0016 (IID), 10.1039/C4RA00354C (DOI)
Keywords: zinc, photophysics, imaging, coordination chemistry
Citation: "Zn(II)-coordination modulated ligand photophysical processes – the development of fluorescent indicators for imaging biological Zn(II) ions " Zhu L.; Yuan Z.; Sreenath K.; Simmons J. T. RSC Advances. 2014.
Subject(s): Cytology
Chemistry, Inorganic
Brain chemistry
Neurochemistry
Neurosciences
Chemistry, Organic
Chemistry, Physical and theoretical
Links: http://dx.doi.org/10.1039/C4RA00354C
Persistent Link to This Record: http://purl.flvc.org/fsu/fd/FSU_migr_chm_faculty_publications-0016
Owner Institution: FSU
Is Part of Series: Department of Chemistry and Biochemistry Faculty Publications.
Is Part Of: RSC Advances.

Choose the citation style.
Zhu, L., Yuan, Z., Simmons, J., & Sreenath, K. (2014). Zn(II)-coordination modulated ligand photophysical processes – the development of fluorescent indicators for imaging biological Zn(II) ions. Rsc Advances. Retrieved from http://dx.doi.org/10.1039/C4RA00354C