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Serotonin Transporter Gene's Association with Mental Disorders

Title: The Serotonin Transporter Gene's Association with Mental Disorders: A Meta Analysis.
Name(s): Brown, Jessica S., author
Joiner, Thomas E., professor directing thesis
Johnson, Frank, committee member
Wagner, Richard, committee member
Department of Psychology, degree granting department
Florida State University, degree granting institution
Type of Resource: text
Genre: Text
Issuance: monographic
Date Issued: 2003
Publisher: Florida State University
Place of Publication: Tallahassee, Florida
Physical Form: computer
online resource
Extent: 1 online resource
Language(s): English
Abstract/Description: In recent years, abnormalities in serotonin functioning have been detected in individuals with a variety of mental illnesses. One gene that helps regulate serotonergic function, the serotonin transporter gene, has been identified and numerous studies have been conducted in an attempt to link this gene to mental illnesses. This meta-analysis takes these often contradictory findings and attempts to draw preliminary conclusions regarding the influence of this gene on mental illness. It was concluded that individuals with major depression and obsessive-compulsive disorder are more likely to carry the s/s genotype but not the s allele. Other disorders, such as bipolar disorder, schizophrenia, and alcohol abuse show no consistent relationship with this gene. Finally, current data suggest a relationship between the serotonin transporter gene and disorders such as anorexia nervosa, bulimia nervosa, and attention deficit/hyperactivity disorder, but further experimental studies are necessary before firm conclusions can be drawn.
Identifier: FSU_migr_etd-2964 (IID)
Submitted Note: A Thesis submitted to the Department of Psychology in partial fulfillment of the requirements for the degree of Master of Science.
Degree Awarded: Fall Semester, 2003.
Date of Defense: August 13, 2003.
Keywords: Serotonin Transporter Gene, Meta Analysis
Bibliography Note: Includes bibliographical references.
Advisory Committee: Thomas E. Joiner, Professor Directing Thesis; Frank Johnson, Committee Member; Richard Wagner, Committee Member.
Subject(s): Psychology
Persistent Link to This Record:
Owner Institution: FSU

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Brown, J. S. (2003). The Serotonin Transporter Gene's Association with Mental Disorders: A Meta Analysis. Retrieved from